ISSN 1674-3865  CN 21-1569/R
主管:国家卫生健康委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

中国中西医结合儿科学 ›› 2021, Vol. 13 ›› Issue (2): 112-.

• 综述 • 上一篇    下一篇

儿童孤独症谱系障碍发病机制的研究进展

占红,白淑霞,王金堂   

  1. 442000 湖北 十堰,湖北医药学院附属人民医院儿童康复科
  • 出版日期:2021-04-25 发布日期:2021-05-18
  • 通讯作者: 王金堂,E-mail:52033572@qq.com
  • 作者简介:占红(1990-),女,医师。研究方向:小儿孤独症的诊治

Research progress in the pathogenesis of autism spectrum disorders in children

ZHAN Hong,BAI Shuxia,WANG Jintang   

  1. Affiliated People′s Hospital of Hubei University of Medicine,Shiyan 442000,China
  • Online:2021-04-25 Published:2021-05-18

摘要: 孤独症谱系障碍(ASD)是一类神经发育障碍性疾病,以兴趣或活动范围狭窄、社交沟通障碍及重复刻板行为为主要临床特征。目前,国内外ASD患病率均呈逐年增长的趋势,关于ASD发病的高危因素是国内外研究的热点,关于其发病机制亦是当下研究的难点,本文从基因分子水平、细胞组织水平、机体水平三大方面对ASD高危险因素的发病机制作一综述,以期能为更好的认知和早期干预ASD提供参考。

关键词: 孤独症谱系障碍, 高危因素, 发病机制

Abstract: Autism spectrum disorders(ASD) are a group of neurodevelopmental disorders characterized by social communication disorder,narrow interest or activity range and repetitive stereotyped behavior.Currently,the prevalence of ASD has been increasing year by year at home and abroad.The high-risk factors of ASD are the research focus at home and abroad,and the pathogenesis is the difficulty of current research.This article reviews the pathogenesis of high-risk factors of autism spectrum disorders from three levels:genetic molecule,cell tissue and human body,in order to provide reference for better cognition and early intervention of ASD.

Key words: Autism spectrum disorders, High-risk factors, Pathogenesis