ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2021, Vol. 13 ›› Issue (5): 392-395.

• 临床研究 • 上一篇    下一篇

足月儿和早产儿神经行为发育水平差异及相关影响因素研究

目的:探讨早产儿神经行为发育水平及差异相关影响因素。
方法:选取2018年7月至2019年6月在我院出生的80例早产儿为研究对象，同期选择在我院出生的80例足月新生儿为对照。使用Bayley-Ⅲ量表，对新生儿的认知能力、语言理解、语言表达、精细运动、大运动5个能区进行评价，同时对新生儿的临床资料进行多因素Logistic分析，由父母填写本院自制的调查问卷，通过单因素与多因素分析影响早产儿神经发育水平和差异的相关因素。
结果:早产儿的认知能力、语言理解、语言表达、精细运动、大运动评分均低于正常的足月儿（P<0.05）；单因素中新生儿的分娩方式（P=0.068）、出生体质量（P=0.000）、出生时身长（P=0.000）、母亲文化程度（P=0.000）、头围（P=0.000）、孕周（P=0.000）与神经行为发育水平相关；多因素Logistic分析中新生儿的出生体质量（P=0.001）、出生时身长（P=0.021）、母亲文化程度（P=0.000）、头围（P=0.014）、孕周（P=0.005）为影响神经行为发育水平的相关因素。
结论:正常足月儿的神经行为发育水平高于早产儿，同时新生儿的出生体质量、身长、母亲文化程度、头围、孕周是影响神经行为发育水平的重要因素。   

  1. 451200 郑州，巩义市人民医院儿科
  • 出版日期:2021-10-25 上线日期:2021-11-17
  • 通讯作者: 柴富强，E-mail：huapo0164@163.com
  • 作者简介:柴富强（1979-），女，主治医师。研究方向：儿童保健与康复
  • 基金资助:
    2019年度河南省医学科技攻关计划（联合共建）项目（LHGJ20191513）

Study on the difference in neurobehavioral development level and related influencing factors between term and premature infants

Objective:To investigate the level of neurobehavioral development of premature infants and the factors related to the differences.#br# Methods:Eighty premature babies born in our hospital from July 2018 to June 2019 were selected as the observation group, and 80 full-term newborns born in our hospital during the same period were selected as the control group. The Bayley-Ⅲ scale was used to evaluate the five energy areas of the newborn: cognitive ability, language understanding, language expression, fine motor, and grand motor. At the same time, the clinical data of the newborn was analyzed by multi-factor logistic;The self-made questionnaire of our hospital was filled in by the parents and the related factors affecting the neurodevelopment level and the differences of preterm infants were analyzed by univariate and multivariate analysis.#br# Results:The scores in cognitive ability, language understanding, language expression, fine motor and grand motor of preterm infants were lower than those of normal term infants(P<0.05); univariate analysis showed that the delivery method(P=0.068), birth weight (P=0.000),body length at birth(P=0.000), mother's education level(P=0.001), head circumference(P=0.000) and gestational age(P=0.000) were related to the level of neurobehavioral development; in the multivariate logistic analysis, newborns' birth weight(P=0.001), body length at birth(P=0.021), mother's education level (P=0.000), head circumference(P=0.014) and gestational age(P=0.005) were related factors affecting the level of neurobehavioral development.#br# Conclusion:The level of neurobehavioral development of normal term infants is higher than that of premature infants. At the same time, the birth weight, body length, mother's education level, head circumference and gestational age of newborns are important factors affecting the level of neurobehavioral development.   

  1. Department of Pediatrics, Gongyi People's Hospital, Zhengzhou 451200，China
  • Published:2021-10-25 Online:2021-11-17

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摘要： 目的:探讨早产儿神经行为发育水平及差异相关影响因素。
方法:选取2018年7月至2019年6月在我院出生的80例早产儿为研究对象，同期选择在我院出生的80例足月新生儿为对照。使用Bayley-Ⅲ量表，对新生儿的认知能力、语言理解、语言表达、精细运动、大运动5个能区进行评价，同时对新生儿的临床资料进行多因素Logistic分析，由父母填写本院自制的调查问卷，通过单因素与多因素分析影响早产儿神经发育水平和差异的相关因素。
结果:早产儿的认知能力、语言理解、语言表达、精细运动、大运动评分均低于正常的足月儿（P<0.05）；单因素中新生儿的分娩方式（P=0.068）、出生体质量（P=0.000）、出生时身长（P=0.000）、母亲文化程度（P=0.000）、头围（P=0.000）、孕周（P=0.000）与神经行为发育水平相关；多因素Logistic分析中新生儿的出生体质量（P=0.001）、出生时身长（P=0.021）、母亲文化程度（P=0.000）、头围（P=0.014）、孕周（P=0.005）为影响神经行为发育水平的相关因素。
结论:正常足月儿的神经行为发育水平高于早产儿，同时新生儿的出生体质量、身长、母亲文化程度、头围、孕周是影响神经行为发育水平的重要因素。

关键词: 神经行为, 发育水平, 早产儿, 足月儿

Abstract: Objective:To investigate the level of neurobehavioral development of premature infants and the factors related to the differences.
Methods:Eighty premature babies born in our hospital from July 2018 to June 2019 were selected as the observation group, and 80 full-term newborns born in our hospital during the same period were selected as the control group. The Bayley-Ⅲ scale was used to evaluate the five energy areas of the newborn: cognitive ability, language understanding, language expression, fine motor, and grand motor. At the same time, the clinical data of the newborn was analyzed by multi-factor logistic;The self-made questionnaire of our hospital was filled in by the parents and the related factors affecting the neurodevelopment level and the differences of preterm infants were analyzed by univariate and multivariate analysis.
Results:The scores in cognitive ability, language understanding, language expression, fine motor and grand motor of preterm infants were lower than those of normal term infants(P<0.05); univariate analysis showed that the delivery method(P=0.068), birth weight (P=0.000),body length at birth(P=0.000), mother's education level(P=0.001), head circumference(P=0.000) and gestational age(P=0.000) were related to the level of neurobehavioral development; in the multivariate logistic analysis, newborns' birth weight(P=0.001), body length at birth(P=0.021), mother's education level (P=0.000), head circumference(P=0.014) and gestational age(P=0.005) were related factors affecting the level of neurobehavioral development.
Conclusion:The level of neurobehavioral development of normal term infants is higher than that of premature infants. At the same time, the birth weight, body length, mother's education level, head circumference and gestational age of newborns are important factors affecting the level of neurobehavioral development.

Key words: Neurobehavior, Developmental level, Preterm infant, Term infant