ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2021, Vol. 13 ›› Issue (5): 413-416.

• 临床研究 • 上一篇    下一篇

309例新生儿振幅整合脑电图分析

目的:对不同疾病的振幅整合脑电图(aEEG)进行分析，探讨其在新生儿脑损伤中的应用价值。
方法:选取我院2018年1月至12月收治住院的有脑损伤高风险状态的新生儿309例，在入院24～48 h内完成aEEG检查进行分析。
结果:足月儿中新生儿高胆红素血症、新生儿缺氧缺血性脑病及新生儿惊厥的aEEG评分比较，差异有统计学意义（P<0.05），缺氧缺血性脑病患儿异常率最高，其次为惊厥患儿。早产儿aEEG评分随着胎龄的不同逐渐变化，逐渐出现连续的电压，睡眠-觉醒周期逐渐成熟。
结论:aEEG是评价新生儿脑功能的重要手段，aEEG异常患儿是出院后随访的重点关注人群。
  

  1. 650034 昆明，昆明市儿童医院新生儿科
  • 出版日期:2021-10-25 上线日期:2021-12-06
  • 通讯作者: 杜琨，E-mail：dukun@etyy.cn
  • 作者简介:杜琨（1967-），女，主任医师。研究方向：新生儿脑损伤与脑保护及新生儿感染性疾病

Analysis of amplitude-integrated EEG in 309 neonates

Objective:To analyze the amplitudeintegrated electroencephalogram (aEEG) of different diseases and explore its application value in neonatal brain injury.#br# Methods:Totally 309 neonates with high risk of brain injury who were admitted to our hospital from January to December of 2018 were selected, and the aEEG examination was completed within 24 to 48 hours after admission for analysis.#br# Results:Hypoxic-ischemic encephalopathy of the newborn, neonatal hyperbilirubinemia, and the aEEG scores of neonatal seizures were compared among term infants, and the difference was statistically significant(P<0.05). The infants with Hypoxic-ischemic encephalopathy had the highest abnormal rate, followed by infants with convulsions. The aEEG score of premature infants changed gradually with different gestational age. Continuous voltage appeared gradually, and the sleep-wake cycle matured gradually. #br# Conclusion:The aEEG is an important method to evaluate neonatal brain function. Infants with abnormal aEEG should be paid much attention during the follow-up after discharge.   

  1. Department of Neonatology, Kunming Children's Hospital，Kunming 650034，China
  • Published:2021-10-25 Online:2021-12-06

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摘要： 目的:对不同疾病的振幅整合脑电图(aEEG)进行分析，探讨其在新生儿脑损伤中的应用价值。
方法:选取我院2018年1月至12月收治住院的有脑损伤高风险状态的新生儿309例，在入院24～48 h内完成aEEG检查进行分析。
结果:足月儿中新生儿高胆红素血症、新生儿缺氧缺血性脑病及新生儿惊厥的aEEG评分比较，差异有统计学意义（P<0.05），缺氧缺血性脑病患儿异常率最高，其次为惊厥患儿。早产儿aEEG评分随着胎龄的不同逐渐变化，逐渐出现连续的电压，睡眠-觉醒周期逐渐成熟。
结论:aEEG是评价新生儿脑功能的重要手段，aEEG异常患儿是出院后随访的重点关注人群。

关键词: 脑损伤, 振幅整合脑电图, 新生儿

Abstract: Objective:To analyze the amplitudeintegrated electroencephalogram (aEEG) of different diseases and explore its application value in neonatal brain injury.
Methods:Totally 309 neonates with high risk of brain injury who were admitted to our hospital from January to December of 2018 were selected, and the aEEG examination was completed within 24 to 48 hours after admission for analysis.
Results:Hypoxic-ischemic encephalopathy of the newborn, neonatal hyperbilirubinemia, and the aEEG scores of neonatal seizures were compared among term infants, and the difference was statistically significant(P<0.05). The infants with Hypoxic-ischemic encephalopathy had the highest abnormal rate, followed by infants with convulsions. The aEEG score of premature infants changed gradually with different gestational age. Continuous voltage appeared gradually, and the sleep-wake cycle matured gradually. 
Conclusion:The aEEG is an important method to evaluate neonatal brain function. Infants with abnormal aEEG should be paid much attention during the follow-up after discharge.

Key words: Brain injury, Amplitude integrated electroencephalogram, Neonates