ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2021, Vol. 13 ›› Issue (4): 340-.

• 临床研究 • 上一篇    下一篇

颅部CT和磁共振成像检查对高胆红素血症患儿脑损伤评价效果的对比分析

目的:观察高胆红素血症患儿分别采用颅脑CT、磁共振成像（MRI）技术检查，分析其脑损伤的诊断与评价结果。
方法:选择2019年2月至2020年4月我院收治的高胆红素血症患儿63例，为观察组；同期选择健康新生儿50例为对照组。分别测定两组新生儿神经测定评分（NBNA）、血清胆红素(TB）水平；并使用颅脑CT、MRI技术进行检查，分析不同检查方法扫描对患儿脑损伤评价结果，以脑干听觉诱发电位测定为金标准。
结果:观察组TB水平显著高于对照组，NBNA评分低于对照组，差异有统计学意义（P<0.05）。对比两种检查方法诊断结果，MRI诊断技术准确率、灵敏度均高于CT技术，差异有统计学意义（P<0.05）。头颅MRI阳性患儿3 d内高胆红素血症发生率为79.41%（27/34），高于头颅MRI阴性患儿17.24%(5/29)，差异有统计学意义（P<0.05）；阳性患儿NBNA评分为（32.50±1.36）分，低于阴性患儿（34.14±1.40）分，差异有统计学意义（P<0.05）。颅脑MRI技术的成本效果比低于颅脑CT技术，MRI技术经济效益更高。
结论:相比于头颅CT技术，对高胆红素血症患儿运用MRI技术诊断准确度、灵敏度更高，联合NBNA评分，可作为早期评价患儿脑损伤的重要方法。   

  1. 515300 广东 揭阳，普宁市人民医院CT室（陈奕州，黄育鑫）；510000 广州，南方医科大学附属第三医院医学影像科（马春浓）
  • 出版日期:2021-08-25 上线日期:2021-12-13
  • 通讯作者: 陈奕州，E-mail：355726210@qq.com
  • 作者简介:陈奕州（1989-），男，主治医师。研究方向：CT和磁共振成像诊断

Comparative analysis of cranial CT and magnetic resonance imaging in the evaluation of brain injury in children with hyperbilirubinemia

Objective:To observe the diagnosis and evaluation of brain injury in children with hyperbilirubinemia by brain CT and magnetic resonance imaging(MRI).#br# Methods:A total of 63 children with hyperbilirubinemia treated in our hospital from February 2019 to April 2020 were selected as the observation group; 50 healthy newborns in the same period were selected as the control group. The NBNA score and TB level were determined; the brain CT and MRI techniques were used and the evaluation results of brain injury in children with different methods were analyzed. The measurement of brainstem auditory evoked potential was the gold standard.#br# Results: The TB level in the observation group was significantly higher than that in the control group, while the NBNA score was lower(P<0.05). Comparing the diagnostic results of the two methods, the accuracy andsensitivity of MRI were higher than those of CT(P<0.05). The incidence of hyperbilirubinemia within 3 days in children with positive cranial MRI was 79.41%(27/34), which was higher than 17.24%(5/29) in children with negative cranial MRI(P<0.05); the NBNA score of positive children was (32.50±1.36), which was lower than that of negative children (34.14±1.40) (P<0.05). The cost-effectiveness ratio of brain MRI technology is lower thanthat of brain CT technology, and the economic benefit of MRI technology is higher.#br# Conclusion: Compared with cranialCT, MRI has higher accuracy and sensitivity in the diagnosisof hyperbilirubinemia in children, and combined with NBNA score, it can be used as an important method for early evaluation of brain injury in children.   

  1. Puning People's Hospital,Jieyang 515300，China
  • Published:2021-08-25 Online:2021-12-13

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摘要： 目的:观察高胆红素血症患儿分别采用颅脑CT、磁共振成像（MRI）技术检查，分析其脑损伤的诊断与评价结果。
方法:选择2019年2月至2020年4月我院收治的高胆红素血症患儿63例，为观察组；同期选择健康新生儿50例为对照组。分别测定两组新生儿神经测定评分（NBNA）、血清胆红素(TB）水平；并使用颅脑CT、MRI技术进行检查，分析不同检查方法扫描对患儿脑损伤评价结果，以脑干听觉诱发电位测定为金标准。
结果:观察组TB水平显著高于对照组，NBNA评分低于对照组，差异有统计学意义（P<0.05）。对比两种检查方法诊断结果，MRI诊断技术准确率、灵敏度均高于CT技术，差异有统计学意义（P<0.05）。头颅MRI阳性患儿3 d内高胆红素血症发生率为79.41%（27/34），高于头颅MRI阴性患儿17.24%(5/29)，差异有统计学意义（P<0.05）；阳性患儿NBNA评分为（32.50±1.36）分，低于阴性患儿（34.14±1.40）分，差异有统计学意义（P<0.05）。颅脑MRI技术的成本效果比低于颅脑CT技术，MRI技术经济效益更高。
结论:相比于头颅CT技术，对高胆红素血症患儿运用MRI技术诊断准确度、灵敏度更高，联合NBNA评分，可作为早期评价患儿脑损伤的重要方法。

关键词: 高胆红素血症, 脑损伤, 头颅CT, 头颅磁共振成像

Abstract: Objective:To observe the diagnosis and evaluation of brain injury in children with hyperbilirubinemia by brain CT and magnetic resonance imaging(MRI).
Methods:A total of 63 children with hyperbilirubinemia treated in our hospital from February 2019 to April 2020 were selected as the observation group; 50 healthy newborns in the same period were selected as the control group. The NBNA score and TB level were determined; the brain CT and MRI techniques were used and the evaluation results of brain injury in children with different methods were analyzed. The measurement of brainstem auditory evoked potential was the gold standard.
Results: The TB level in the observation group was significantly higher than that in the control group, while the NBNA score was lower(P<0.05). Comparing the diagnostic results of the two methods, the accuracy andsensitivity of MRI were higher than those of CT(P<0.05). The incidence of hyperbilirubinemia within 3 days in children with positive cranial MRI was 79.41%(27/34), which was higher than 17.24%(5/29) in children with negative cranial MRI(P<0.05); the NBNA score of positive children was (32.50±1.36), which was lower than that of negative children (34.14±1.40) (P<0.05). The cost-effectiveness ratio of brain MRI technology is lower thanthat of brain CT technology, and the economic benefit of MRI technology is higher.
Conclusion: Compared with cranialCT, MRI has higher accuracy and sensitivity in the diagnosisof hyperbilirubinemia in children, and combined with NBNA score, it can be used as an important method for early evaluation of brain injury in children.

Key words: Hyperbilirubinemia, Brain injury, Cranial CT, Cranial magnetic resonance imaging