ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2021, Vol. 13 ›› Issue (4): 362-.

• 小儿中药应用研究 • 上一篇    下一篇

桑白皮汤加减治疗小儿类百日咳综合征的优良效果分析

目的: 探究对小儿类百日咳综合征患儿施行桑白皮汤加减治疗的效果。
方法: 选择2017年1月至2019年12月我院收治小儿类百日咳综合征患儿40例，随机分为对照组和观察组各20例。对照组施行阿奇霉素治疗，观察组在对照组基础上施行桑白皮汤加减治疗。对比两组治疗总有效率、炎性因子水平、肺功能指标、主要症状消失时间、血常规恢复正常时间、住院时间。
结果: 观察组治疗总有效率为95.0%（19/20），高于对照组65.0%（13/20），差异有统计学意义（P<0.05）。观察组治疗后呼吸频率较对照组更低，且治疗后潮气量、吸呼比较对照组更高，差异有统计学意义（P<0.05）。观察组治疗后白细胞计数、C反应蛋白水平均较对照组更低，差异有统计学意义（P<0.05）。观察组主要症状消失时间、血常规恢复正常时间、住院时间均较对照组更短，差异有统计学意义（P<0.05）。
结论: 对小儿类百日咳综合征患儿施行桑白皮汤加减治疗有助于增强疗效，改善患儿肺功能，减轻炎症反应，加速病情恢复。   

  1. 526500 广东 阳江，阳江市人民医院儿科
  • 出版日期:2021-08-25 上线日期:2021-12-13
  • 通讯作者: 林倩雯，E-mail：594011105@qq.com
  • 作者简介:麦月嫦(1985-)，女，主治中医师。研究方向：中西医结合治疗儿科疾病及易感儿体质调理
  • 基金资助:
    阳江市科学技术局项目［阳科通（2019）50号-3］

Analysis of the curative effect of modified Sangbaipi decoction on pertussis-like syndrome in children

Objective: To explore the effect of modified Sangbaipi decoction on children with pertussis-like syndrome.#br# Methods: Forty cases of children withpertussis-like syndrome treated in our hospital from January 2017 to December 2019 were randomly divided into control group(20 cases, treated with azithromycin) and observation group(20 cases, treated with Sangbaipi decoction and azithrpmycin). The total effective rate, inflammatory factor level, pulmonary function index, disappearance time of main symptoms, recovery time of blood routine and hospitalization time were compared between the two groups.#br# Results: The total effective rate of the observation group(95.0%,19/20) was higher than that of the control group(65.0%,13/20)(P<0.05);the respiratory rate of the observation group after treatment was lower than that of the control group, and the tidal volume and inspiration/expiration ratio after treatment were higher than those of the control group(P<0.05); the white blood cell count and C-reactive protein level in the observation group werelower than those in the control group(P<0.05); the disappearance time of main symptoms and the recovery time of blood routine in the observation group were all lower than those in the control group(P<0.05). Compared with thecontrol group, the hospitalization time was shorter(P<0.05).#br# Conclusion: The application of modified Sangbaipi decoction in the treatment of children with pertussis-like syndrome is helpful to enhance the curative effect, improve the lung function, reduce the inflammatory reaction and accelerate the recovery of the disease.   

  1. Department of Pediatrics, Yangjiang People's Hospital,Yangjiang 526500,China
  • Published:2021-08-25 Online:2021-12-13

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摘要： 目的: 探究对小儿类百日咳综合征患儿施行桑白皮汤加减治疗的效果。
方法: 选择2017年1月至2019年12月我院收治小儿类百日咳综合征患儿40例，随机分为对照组和观察组各20例。对照组施行阿奇霉素治疗，观察组在对照组基础上施行桑白皮汤加减治疗。对比两组治疗总有效率、炎性因子水平、肺功能指标、主要症状消失时间、血常规恢复正常时间、住院时间。
结果: 观察组治疗总有效率为95.0%（19/20），高于对照组65.0%（13/20），差异有统计学意义（P<0.05）。观察组治疗后呼吸频率较对照组更低，且治疗后潮气量、吸呼比较对照组更高，差异有统计学意义（P<0.05）。观察组治疗后白细胞计数、C反应蛋白水平均较对照组更低，差异有统计学意义（P<0.05）。观察组主要症状消失时间、血常规恢复正常时间、住院时间均较对照组更短，差异有统计学意义（P<0.05）。
结论: 对小儿类百日咳综合征患儿施行桑白皮汤加减治疗有助于增强疗效，改善患儿肺功能，减轻炎症反应，加速病情恢复。

关键词: 类百日咳综合征, 桑白皮汤, 炎性因子, 肺功能, 儿童

Abstract: Objective: To explore the effect of modified Sangbaipi decoction on children with pertussis-like syndrome.
Methods: Forty cases of children withpertussis-like syndrome treated in our hospital from January 2017 to December 2019 were randomly divided into control group(20 cases, treated with azithromycin) and observation group(20 cases, treated with Sangbaipi decoction and azithrpmycin). The total effective rate, inflammatory factor level, pulmonary function index, disappearance time of main symptoms, recovery time of blood routine and hospitalization time were compared between the two groups.
Results: The total effective rate of the observation group(95.0%,19/20) was higher than that of the control group(65.0%,13/20)(P<0.05);the respiratory rate of the observation group after treatment was lower than that of the control group, and the tidal volume and inspiration/expiration ratio after treatment were higher than those of the control group(P<0.05); the white blood cell count and C-reactive protein level in the observation group werelower than those in the control group(P<0.05); the disappearance time of main symptoms and the recovery time of blood routine in the observation group were all lower than those in the control group(P<0.05). Compared with thecontrol group, the hospitalization time was shorter(P<0.05).
Conclusion: The application of modified Sangbaipi decoction in the treatment of children with pertussis-like syndrome is helpful to enhance the curative effect, improve the lung function, reduce the inflammatory reaction and accelerate the recovery of the disease.

Key words: Pertussis-like syndrome, Sangbaipi decoction, Inflammatory factors, Lung function, Child