ISSN 1674-3865  CN 21-1569/R
主管:国家卫生健康委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

中国中西医结合儿科学 ›› 2023, Vol. 15 ›› Issue (3): 199-202.

• 综述 • 上一篇    下一篇

宏基因组二代测序用于儿童呼吸道感染性疾病诊断的应用进展

  

  • 出版日期:2023-06-25 上线日期:2023-11-22

Application of metagenomic next generation sequencing in the diagnosis of respiratory infectious diseases in children

  • Published:2023-06-25 Online:2023-11-22

摘要: 呼吸道感染是儿童最常见的感染,严重威胁儿童生命健康,早期明确病原体对于该类疾病的临床诊治有重要意义。宏基因组二代测序(mNGS)具备无偏倚、全覆盖、高效率等优势,正被应用于临床感染性疾病诊断。本文通过一系列实例来介绍mNGS在儿童呼吸道感染性疾病中的应用价值

关键词: 呼吸道感染, 宏基因组二代测序, 应用, 儿童

Abstract: Respiratory tract infection is the most common infection in children,which seriously threatens the life and health of children.Early identification of pathogens is of great significance for the clinical diagnosis and treatment of such diseases.Metagenomic next generation sequencing(mNGS) has the advantages of unbiasedness,full coverage and high efficiency,and is now being applied to clinical diagnosis of infectious diseases.This article introduces the application value of mNGS in children′s respiratory infectious diseases through a series of examples.

Key words:

Respiratory infection, Metagenomic next generation sequencing, Application, Children