ISSN 1674-3865  CN 21-1569/R
主管:国家卫生健康委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

中国中西医结合儿科学 ›› 2023, Vol. 15 ›› Issue (3): 203-207.

• 综述 • 上一篇    下一篇

儿童原发性肾病综合征糖皮质激素性眼损害的相关研究

  

  • 出版日期:2023-06-25 上线日期:2023-11-22

Study on glucocorticoid-induced eye damage in children with primary nephrotic syndrome

  • Published:2023-06-25 Online:2023-11-22

摘要: 原发性肾病综合征是儿童最常见的肾小球疾病之一。长期口服糖皮质激素是原发性肾病综合征公认的一线治疗方案。由于长期使用糖皮质激素会导致高眼压、青光眼、白内障等眼部损害。本文将对原发性肾病综合征糖皮质激素性眼损害的流行病学、风险因素、发病机制、诊断及临床表现、临床管理和治疗进行综述。建立原发性肾病综合征患儿长期糖皮质激素治疗过程中眼损害的早筛查、早诊断、早治疗,有效保证儿童眼健康。

关键词: 原发性肾病综合征, 糖皮质激素, 眼损害, 儿童

Abstract: Primary nephrotic syndrome (PNS) is one of the most common glomerular diseases in children.Long-term oral glucocorticoids are recognized as the first-line treatment for PNS.Long-term use of glucocorticoids can lead to eye damage such as high eye pressure,glaucoma and cataracts.This article reviews the epidemiology,risk factors,pathogenesis,diagnosis,clinical manifestations,clinical management and treatment of glucocorticoid-induced eye damage in PNS.By establishing early screening,early diagnosis and early treatment of eye damage in PNS children during long-term glucocorticoid therapy,we hope to effectively ensure children′s eye health.

Key words: Primary nephrotic syndrome, Glucocorticoid, Eye damage, Children