ISSN 1674-3865  CN 21-1569/R
主管:国家卫生健康委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

中国中西医结合儿科学 ›› 2023, Vol. 15 ›› Issue (3): 262-267.

• 小儿中药应用研究 • 上一篇    下一篇

基于《中华医典》中医药治疗小儿湿疹用药规律探析

  

  • 出版日期:2023-06-25 上线日期:2023-11-22

Medication rules of Chinese medicines in the treatment of pediatric eczema based on the Chinese Medical Classics

  • Published:2023-06-25 Online:2023-11-22

摘要: 目的 探析古籍中治疗小儿湿疹的用药规律。方法 收集整理《中华医典》中治疗小儿湿疹的方剂,进行数据的频次、性味归经、关联规则、聚类等分析。结果 外用高频药物有轻粉、白矾、黄连等,内服有甘草、茯苓、柴胡等。性味归经统计显示外用辛味最多,内服苦味最多,外用肝经最多,内服肺经最多,均为寒性最多。外用毒性药物占比32.49%。外用关联性较强的是“白矾-蛇床子”“黄连-黄柏”。内服关联性较强的是“荆芥-防风”“枳壳-桔梗”。结论 古籍中治疗小儿湿疹的处方,外治以化腐生肌、攻毒杀虫、清热燥湿为主,内治以疏风清热,燥湿止痒为主。外用处方药物主以辛寒,首入肝经;内服主以苦寒,首入肺经。

关键词: 小儿湿疹, 数据挖掘, 用药规律

Abstract: ObjectiveTo study the rules of medication in the treatment of pediatric eczema in ancient medical books.MethodsThe prescriptions for treating pediatric eczema in the Chinese Medical Classics were collected and sorted.The frequency,and the properties,flavor,and meridian tropism of the medicines were analyzed.The methods such as the association rules analysis and cluster analysis were also used.ResultsHigh-frequency drugs for external use included Qingfen(Calomelas),Baifan(Alumen),Huanglian(Rhizomacoptidis),etc.,and Gancao(Radix et Rhizomaglycyrrhizae),Fuling(Poria),Chaihu(Radix bupleuri),etc.,for internal use.The statistical analysis showed that spicy drugs were mostly used for external use,bitter for internal use,and hepatic meridian for external use,lung meridian for internal use.Drugs with cold properties were used most frequently.Toxic drugs for external use accounted for 32.49%.The strong correlation among external drugs was Baifan-Shechuangzi(Fructuscnidii) and Huanglian-Huangbo(Cortex phellodendrichinensis).For internal use strong correlation existed in Jingjie(Herbaschizonepetae)-Fangfeng(Radix saposhnikoviae) and Zhiqiao(Fructusaurantii)-Jiegeng(Radix platycodonis).ConclusionIn ancient medical books,the external treatment for pediatric eczema is mainly to remove rotten ecrotic muscle and promote the growth of granulation,attack poison and kill insects,and clear heat and dry dampness,while the internal treatment is mainly to remove wind and heat,dry dampness and relieve itching.Drugs for external use are mainly spicy and cold,mainly functioning through the hepatic meridian;drugs for internal use are mainly bitter and cold,mainly functioning through the lung meridian.

Key words:

Pediatric eczema, Data mining, Medication rule