ISSN 1674-3865  CN 21-1569/R
主管:国家卫生健康委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

中国中西医结合儿科学 ›› 2023, Vol. 15 ›› Issue (2): 133-137.

• 临床研究 • 上一篇    下一篇

矮小症儿童临床特征及相关危险因素分析

  

  • 出版日期:2023-04-25 上线日期:2023-11-22

Analysis of clinical features and related risk factors in children with short stature

  • Published:2023-04-25 Online:2023-11-22

摘要: 目的 分析矮小症发病相关危险因素。方法 选取2021年6~10月于成都中医药大学附属医院儿童生长发育门诊就诊矮小症儿童57例,并纳入年龄、性别相匹配的正常身高发育水平儿童123例。通过问卷形式采集病史,利用SPSS软件对个人史、家族史、一般资料、生活方式等影响因素进行统计分析。结果 单因素分析显示,年龄、性别、出生季节、辅食添加时间、辅食添加季节、母亲妊娠情况、出生胎龄、生产方式、有无产伤与矮小症的发生无关,是否患有基础疾病、出生体质量、6个月前喂养方式、家族性矮小史、运动方式及运动量、补钙情况、睡眠习惯均与矮小症的发病有关。二元Logistic分析显示,低出生体质量、6个月前混合喂养、家族性矮小史等与矮小发病呈正相关,无基础疾病、充足弹跳运动量、足量夜间睡眠时间与矮小发病呈负相关。结论 矮小症发生受遗传和环境等多种因素影响,其中低出生体质量、家族性矮小史是矮小发病的危险因素,充足弹跳运动量、足量夜间睡眠时间是矮小发病的保护因素。

关键词: 矮小症, 危险因素, 回归分析, 临床特征

Abstract: ObjectiveTo analyze the related risk factors of short stature. MethodsFrom June 2021 to October 2021, 57 short children and 123 children with normal height and development level matched by age and gender were enrolled from the Pediatric Growth and Development Clinic of the Affiliated Hospital of Chengdu University of Traditional Chinese Medicine. The medical history was collected by questionnaire, and SPSS software was used for statistical analysis of personal history, family history, general information, lifestyle and other influencing factors. ResultsSingle factor analysis showed that age, gender, birth season, time of feeding solid food, season of feeding solid food, state of mother pregnancy, gestational age at birth, mode of delivery, and being with or without birth injury had nothing to do with the occurrence of short stature; being with or without basic diseases, birth weight, feeding ways in the first 6 months, family history of short stature, exercise mode and amount, calcium supplementation and sleep habits were related to the onset of short stature. Binary logistic analysis showed that low birth weight, mixed feeding in the first 6 months, and a family history of short stature were positively correlated with the onset of short stature, while the absence of underlying diseases, adequate bouncing exercise, and sufficient night sleep were negatively correlated with the onset of stature. ConclusionThe occurrence of short stature is influenced by various hereditary and environmental factors, among which low birth weight and a family history of short stature are risk factors, while adequate amount of bouncing exercise and sufficient night sleep are protective factors for the onset of short stature.

Key words:

Short stature, Risk factors, Regression analysis, Clinical features