ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2023, Vol. 15 ›› Issue (2): 161-164.

• 调查研究 • 上一篇    下一篇

原发性免疫缺陷患儿注意缺陷多动障碍多发原因调查与中西医病因探讨

  

  • 出版日期:2023-04-25 上线日期:2023-11-22

Investigation into the causes of frequently-occurring attention deficit hyperactivity disorder in children with primary immunodeficiency and discussion on the causes based on traditional Chinese and western medicine

  • Published:2023-04-25 Online:2023-11-22

PDF (PC)

2

摘要： 目的 探讨原发性免疫缺陷病(PID)患儿注意缺陷多动障碍(ADHD)的发病率以及发病原因。方法 2021年11月至2022年4月，在PID患者自发创建的患者群中(均经过专科医师确诊)发布ADHD调查问卷，该问卷使用斯诺佩评估量表(SNAP-Ⅳ,家长版),由年龄为6～18岁的患儿家属自发填写，每条症状评定采用Likert4分法(0分：完全没有，1分：有一点点，2分：还算不少，3分：非常的多),对总量表的项目得分均分进行等级划分：轻度(1～1.5分)、中度(>1.5～2分)、重度(>2分)。结果 在68名PID患儿中有15名患有ADHD,发病率为22.05%,其中男童12名，女童3名。在62名免疫缺陷类型为X-连锁无丙种球蛋白血证(XLA)的免疫缺陷患儿中有12名患有ADHD,发病率为19.35%,其中男童11名，女童1名。结论 PID患儿的ADHD发病具有高发性，对PID患儿的ADHD防治要做到多方面的干预，例如减少上呼吸道感染的发生，增加对父母的积极心理教育。

关键词: 原发性免疫缺陷病, 注意缺陷多动障碍, 中西医病因

Abstract: ObjectiveTo explore the incidence and causes of attention deficit hyperactivity disorder (ADHD) in children with primary immunodeficiency disease (PID).MethodsFrom November,2021 to April,2022,a questionnaire(SNAP-Ⅳ,parents edition) on attention deficit hyperactivity disorder (ADHD) was sent to the group of patients spontaneously created by PID patients (all diagnosed by specialists).The questionnaire was filled out spontaneously by family members of children aged 6 to18 years,and each symptom was evaluated by Likert4-point method (0:none,1:a little,2:quite a little,3:much), and the average of the total scores were graded: mild(1 to 1.5),moderate(＞1.5 to 2), and severe(>2).ResultsAmong 68 children with PID,15 children had attention deficit hyperactivity disorder (ADHD),and the incidence rate was 22.05%,including 12 boys and 3 girls.Among 62 immunodeficiency children with X- linked agammaglobulinemia(XLA),12 children had ADHD,and the incidence rate was 19.35%,including 11 boys and 1 girl.ConclusionThe incidence of ADHD in children with PID is high,so it is necessary to intervene in many aspects to prevent and treat ADHD in children with PID,such as reducing the incidence of upper respiratory tract infection and increasing positive psychological education for parents.

Key words:

Primary immunodeficiency disease, Attention deficit hyperactivity disorder, Etiology based on traditional Chinese and western medicine