ISSN 1674-3865  CN 21-1569/R
主管:国家卫生健康委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

中国中西医结合儿科学 ›› 2023, Vol. 15 ›› Issue (1): 61-66.

• 小儿中药应用研究 • 上一篇    下一篇

基于数据挖掘《幼科杂病心法要诀》治疗小儿疳证用药规律

  

  • 出版日期:2023-02-25 上线日期:2023-11-22

Mining of rules of medication by Youke Zabing Xinfa Yaojue in the treatment of infantile malnutrition based on data

  • Published:2023-02-25 Online:2023-11-22

摘要: 目的 挖掘《幼科杂病心法要诀》中治疗小儿疳证的临床用药规律。方法 从《幼科杂病心法要诀》提取治疗小儿疳证的方药信息,建立“《幼科杂病心法要诀》治疗小儿疳证用药的数据库”,同时采用频数统计、关联规则和聚类分析数据挖掘方法,对方药规律进行分析。结果 共累计内服方剂46首,涉及中药124味,共计频次498次。甘草、黄连、茯苓、胡黄连等药物为常用药物。药物以补虚、清热药为主,药性寒、温居多,多归于脾胃二经。关联规则显示补虚药与补虚药、清热药与杀虫药、清热药与消食药之间存在较大的关联性。核心处方以肥儿丸进行加减,同时可分为3类处方。结论 著作中治疗小儿疳证重视立足脾胃,用药寒温并用,攻补同行。

关键词: 疳证, 《幼科杂病心法要诀》, 用药规律, 儿童

Abstract: ObjectiveTo explore the clinical medication rules by Youke Zabing Xinfa Yaojue in the treatment of children with infantile malnutrition.MethodsExtract the medical records and prescriptions of infantile malnutrition from Youke Zabing Xinfa Yaojue,and establish the "Database of Youke Zabing Xinfa Yaojue medications for infantile malnutrition";meanwhile,the data mining methods(frequency statistics,association rules and cluster analysis) were used to analyze the clinical medication rules.ResultsA total of 46 prescriptions were selected,involving 124 kinds of Chinese medicines,with the frequency of application being 498.The commonly used hetbs included Licorice,Coptis chinensis,Poria cocos and Radix Picrorrhizae,etc. The herbs tonifying deficiency and antipyretic drugs accounted for the major part. The herbs with cold and warm nature accounted for a large proportion,mostly functioning through the spleen and stomach meridian. Association rules showed that there was close correlation between deficiency-nourishing drugs and deficiency-nourishing drugs,between heat-clearing drugs and anthelmintic drugs,as well as between heat-clearing drugs and digestant drugs. The core prescription was Fattening Baby Pill. It could be divided into three categories.ConclusionIn the book,the treatment for infantile malnutrition should be based on the spleen and stomach,and the cold and warm drugs should be used at the same time,to attack the disease and tonify the body.

Key words:

Malnutrition, Youke Zabing Xinfa Yaojue, Medication rules;Children