中文版Morisky用药依从性问卷在儿童哮喘中的信效度评价与应用

摘要/Abstract

摘要： 目的对中文版Morisky用药依从性问卷(MMAS-8)在哮喘儿童中的信度及效度进行评价，研究哮喘儿童影响用药依从性的相关因素。方法选取2021年1月至2022年6月在盐城市儿童医院呼吸科门诊收治的哮喘的患儿进行问卷调查，选用克隆巴赫信度系数(Cronbach α)进行内部一致性信度评价，采用KMO(Kaiser Meyer Olkin)和Bartlett进行效度检验。同时采用多因素多分类有序Logistic回归分析哮喘儿童用药依从性相关独立影响因素。结果本次共筛选符合要求的哮喘儿童130例，回收有效问卷126份。中文版MMAS-8问卷的Cronbach α值为0.724,KMO值为0.741,Bartlett′s球形检验的χ2为248.19(P<0.01)。患儿高用药依从性与近半年发作次数≤1次、监护人是父母、对哮喘药物及疾病认知度高及病程>1年具有显著相关性。结论中文版Morisky在哮喘儿童中的具有很好的信度和效度，调查中患儿用药依从性差与监护人、近半年发作次数、对哮喘药物及疾病认知度及病程具有相关性。

关键词: 哮喘, 依从性, 信效度, Logistic回归

Abstract: ObjectiveTo evaluate the reliability and validity of Chinese version of Morisky medication adherence scale（MMAS-8） in asthmatic children，and to study the related factors affecting medication compliance in asthmatic children.MethodsThe children with asthma admitted to the Respiratory Clinic of Yancheng Children's Hospital from January 2021 to June 2022 were selected for a questionnaire survey. Cronbach α was used for internal consistency reliability evaluation，and Kaiser Meyer Olkin and Bartlett were used for validity testing. Multivariate ordinal Logistic regression was also used to analyze the independent factors associated with medication compliance in asthmatic children.ResultsA total of 130 children with asthma who met the requirements were screened and 126 valid questionnaires were returned. The Cronbach α value of the Chinese version of the MMAS-8 questionnaire was 0.724，the KMO value was 0.741，and the χ2 of Bartlett 's spherical test was 248.19（P＜0.01）.High medication compliance was significantly associated with ≤ 1 episode in the past six months，guardian being a parent，high awareness of asthma drugs and diseases，and disease duration＞1 year.ConclusionThe Chinese version of Morisky has good reliability and validity in children with asthma，and poor medication compliance in children in the survey is correlated with guardians，number of attacks in the past six months，awareness of asthma drugs and diseases，and course of disease.

Key words:

Asthma；Compliance, Reliability and validity, Logistic regression

黄磊, 胡晔, 尹存林, 顾雨芹, . 中文版Morisky用药依从性问卷在儿童哮喘中的信效度评价与应用[J]. 中国中西医结合儿科学, 2023, 15(1): 76-80.

HUANG Lei, HU Ye, YIN Cunlin, GU Yuqin.Yancheng. Evaluation of reliability and validity of Chinese Morisky medication adherence scale and its application in childhood asthma[J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2023, 15(1): 76-80.

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中文版Morisky用药依从性问卷在儿童哮喘中的信效度评价与应用

Evaluation of reliability and validity of Chinese Morisky medication adherence scale and its application in childhood asthma

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