ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2022, Vol. 14 ›› Issue (6): 532-538.

• 中医应用研究 • 上一篇    下一篇

基于复杂网络技术探讨针刺治疗儿童孤独症谱系障碍的选穴规律

  

  • 出版日期:2022-12-25 上线日期:2023-11-23

Analysis on rules of acupoint selection for children with autism spectrum disorder receiving acupuncture treatment based on complex network technique

  • Published:2022-12-25 Online:2023-11-23

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摘要： 目的 基于复杂网络技术探析临床针刺治疗儿童孤独症谱系障碍的核心穴位及相关腧穴配伍规律。方法 收集2022年4月前收录在中国知网(CNKI)、万方数据知识服务平台、维普期刊资源整合服务平台、中国生物医学文献服务系统(CBM)、PubMed和Web of science数据库中公开发表的针刺治疗儿童孤独症谱系障碍的临床研究文献，采用Microsoft Excel 2019建立数据库，运用SPSS Modeler 18.0软件进行腧穴的关联规则分析，然后利用Gephi 0.9.2软件进行复杂网络分析并对示意图进行展示。结果 最终纳入128篇符合标准的文献，提取出244条针刺治疗儿童孤独症谱系障碍的腧穴处方，共涉及154个腧穴，腧穴使用总频次为2 437次，据频次统计与复杂网络k-core分析，针刺治疗儿童孤独症谱系障碍的核心腧穴主要是“靳三针”疗法组穴，且关联规则分析同样显示“靳三针”组穴在针刺治疗儿童孤独症谱系障碍处方中关联度最高。靳三针疗法外，据Gephi分析表明百会、足三里、内关、四神聪、神庭、神门等腧穴度值较高，这些腧穴同样是临床针刺治疗儿童孤独症谱系障碍的重要选穴。结论 针刺治疗儿童孤独症谱系障碍所选腧穴主要分布在头部，以局部取穴为主，“靳三针”疗法应用最多，临床重视“治神”与“调神”。

关键词: 孤独症谱系障碍, 针刺, 复杂网络分析, 腧穴配伍, 儿童

Abstract: ObjectiveTo explore the core acupoints and compatibility rules of related acupoints in clinical acupuncture treatment for children with autism spectrum disorder(ASD) based on complex network technique.MethodsThe relevant articles of clinical trials on acupuncture treatment for children with autism spectrum disorder(ASD) were retrieved from CNKI, WanFang,VIP, CBM, PubMed and Web of Science published before April 2022.The database was established by using Microsoft Excel 2019.By using SPSS Modeler 18.0 software, the association rules of acupoints was analyzed, and then by using Gephi 0.9.2 software the complex network was analyzed and the complex network diagram was demonstrated.ResultsFinally, a total of 128 eligible articles containing 244 acupoint prescriptions and 154 acupoints were extracted.The total frequency of use of the 154 acupoints was 2 437.According to the frequency statistics and complex network k-core analysis,the core acupoints of clinical acupuncture treatment for ASD were mainly the acupoints selection of Jin's Three Needling therapy. Moreover, the association rules analysis also showed that the acupoints selection of Jin's Three Needling therapy had the highest correlation in the prescription of acupuncture for children with ASD. In addition to Jin's Three Needling therapy, according to Gephi analysis, acupoints such as Baihui(DU20), Zusanli(ST36), Neiguan(PC6), Sishencong(EX-HN1), Shenting(DU24), and Shenmen(HT7) had the higher value.These acupoints were also important acupoints in the treatment of children with ASD.ConclusionThe acupoints selected for acupuncture treatment for children with ASD are mainly distributed in the head, and local acupoints are mainly selected. Jin's Three Needling therapy is the most widely used, and clinical attention is paid to governing and regulating the mind.

Key words:

Autism spectrum disorder, Acupuncture, Complex network analysis, Acupoint combinations；Children