ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2022, Vol. 14 ›› Issue (5): 413-419.

• 临床研究 • 上一篇    下一篇

6月龄内小婴儿川崎病冠状动脉病变超声心动图评估标准的对比研究

  

  • 出版日期:2022-10-25 上线日期:2023-11-24

A comparative study on the evaluation criteria of coronary artery lesions by echocardiography in infants below 6 months with Kawasaki disease

  • Published:2022-10-25 Online:2023-11-24

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摘要： 目的 对比分析超声心动图绝对值法与Kobayashi、Dallaire两种Z值计算方法评估6月龄内小婴儿川崎病(KD)冠状动脉病变(CAL)的结果。方法 选择2019年1月至2020年12月于徐州医科大学附属徐州儿童医院心血管内科住院治疗的6月龄内川崎病患儿，超声心动图测量各主要冠状动脉节段的内径，比较绝对值法与Kobayashi(KZ法)、Dallaire(DZ法)两种Z值计算方法的CAL检出率，并对各冠状动脉节段两种Z值的结果进行一致性分析。结果 绝对值法评估CAL共37例(43.5%),KZ法评估CAL共72例(84.7%),DZ法评估CAL共63例(74.1%),KZ法和DZ法较绝对值法分别高出了0.95倍、0.70倍(P<0.001)。女孩右冠状动脉与男孩左前降支两种Z值结果的一致性相对较差。结论 评估6月龄内的小婴儿川崎病的冠状动脉，经体表面积校正的Z值法判断CAL的程度要远大于绝对值法。

关键词: 川崎病, 冠状动脉病变, 超声心动图, 6月龄内婴儿, Z值, 一致性

Abstract: ObjectiveTo compare the echocardiographic absolute value method with two Z socres(Kobayashi and Dallaire) calculation methods in evaluating the results of coronary artery lesions(CAL) in infants below 6 months with Kawasaki disease(KD).MethodsThe infants below 6 months with KD who were hospitalized in the Department of Cardiology, Xuzhou Children's Hospital，Xuzhou Medical University from January 2019 to December 2020 were selected. The internal diameters of major coronary artery segments were measured by echocardiography, and the CAL detection rates by absolute value method, Kobayashi(KZ method) and Dallaire(DZ method) were compared. Two Z socres of major coronary artery segments were analyzed for consistency.ResultsThere were 72 cases(84.7%) of CAL according to KZ, 63 cases(74.1%) according to DZ method, which was 0.95 times and 0.70 times higher than 37 cases（43.5%） according to absolute value method, respectively(P＜0.001). The two Z socres of girls' RCA and boys' LAD were relatively poor in consistency.ConclusionIn evaluating coronary artery of infants below 6 months with KD, the degree of CAL judgment by BSA-corrected Z score method is much greater than that by absolute value method.

Key words:

Kawasaki disease, Coronary artery lesions, Echocardiography, Infants below 6 months, Z score, Consistency