ISSN 1674-3865  CN 21-1569/R
主管:国家卫生健康委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

中国中西医结合儿科学 ›› 2022, Vol. 14 ›› Issue (5): 424-427.

• 临床研究 • 上一篇    下一篇

神经发育疗法的早期介入对高危早产儿神经发育的影响

  

  • 出版日期:2022-10-25 上线日期:2023-11-24

Effect of early intervention by neurodevelopmental therapy on neurodevelopment of high-risk premature infants

  • Published:2022-10-25 Online:2023-11-24

摘要: 目的 观察神经发育疗法(NDT)的早期介入对高危早产儿神经发育的影响并分析高危早产儿康复干预的敏感指标。方法 选取2019年9月至2021年9月我院出生的早产高危儿82例进行研究,向家属告知早产高危儿的脑损伤风险与干预方式,自愿选择常规家庭干预42例为对照组和NDT康复40例为观察组。两组均干预6个月,观察两组患儿干预前后神经系统发育改善程度:包括肌张力、神经系统反射、生长发育(发育商)。结果 两组干预前肌张力比较差异无统计学意义(P>0.05)。两组患儿干预前神经反射(正常数量)与发育商比较差异无统计学意义(P>0.05),干预后比较差异有统计学意义(P<0.01)。采用Pearson进行相关性分析,结果表明神经反射(正常数量)与发育商相关(r=0.829,P<0.01)。结论 早产高危儿的神经系统反射检查异常,结合肌张力和生长发育评估,需及时对患儿进行NDT康复干预。临床上可以将神经系统反射正常水平作为早产高危儿康复干预的敏感指标。

关键词: 早产儿, 高危儿, 神经发育疗法, 神经发育

Abstract: ObjectiveTo observe the effect of intervention by neurodevelopmental therapy(NDT) on neurodevelopment of high-risk preterm infants and the sensitive indicators by rehabilitation intervention in high-risk preterm infants.MethodsA total of 82 cases of preterm high-risk infants borned in our hospital from September 2019 to September 2021 were selected and randomly grouped into control group and intervention group.The family members were told about the risks of brain injury and ways of intervention in preterm high-risk infants.The control group(42 cases) was the conventional family rehabilitation group, and the intervention group(40 cases) was the NDT rehabilitation group. Both groups were intervened for 6 months to observe the degree of neurodevelopmental improvement after the intervention, including muscle tone, nervous system reflexes, growth and development(development quotient). ResultsThere was no statistical significance in the difference between the two groups before the intervention(P>0.05); there was no statistical difference in neural reflexes and development quotients between the two groups before the intervention(P>0.05), but there were statistically significant differences between the two groups after the intervention(P<0.01). The Pearson correlation analysis was made and the results showed that the normal number of neural reflexes was related to the development quotient(r=0.829,P<0.01).ConclusionAbnormal neuroreflex examination in high-risk preterm infants, combined with muscle tone and growth development assessment,calls for NDT rehabilitation intervention in the children. Normal levels of neuroreflex can be clinically used as a sensitive indicator of rehabilitation interventions in high-risk preterm infants.

Key words:

Premature infants, High-risk children, Neurodevelopmental therapy, Neurodevelopment