关键词:

咳嗽变异性哮喘, 发病因素, Logistic回归, 儿童

Abstract:

ObjectiveTo explore the related factors of cough variant asthma(CVA) in children in order to provide reference for clinical work.MethodsSelect 40 children with cough variant asthma and 40 healthy children to ask them to fill out a questionnaire on related factors，including gender，age，body mass index，history of allergic rhinitis，history of atopic dermatitis，history of allergic conjunctivitis，history of recurrent respiratory tract infections，history of asthma or chronic cough in grade 1，2 parents，atopic physique (urticaria，eczema，rhinitis) of grade 1，2 parents，history of smoke exposure (including passive smoking，kitchen oil fume，air pollution)，keeping pets or planting flowers and plants at home，laying carpets at home，delivery mode，feeding methods and peripheral blood eosinophils，etc.First perform single factor analysis to remove irrelevant factors，and then perform Logistic regression analysis，and finally get the factors related to the onset of cough variant asthma in children.ResultsAfter univariate analysis and logistic regression analysis，history of allergic rhinitis(P=0.002)，history of recurrent respiratory infections(P=0.015) and feeding methods(P=0.049) were related factors for the onset of cough variant asthma in children.ConclusionThe onset of cough variant asthma in children is related to history of allergic rhinitis，history of recurrent respiratory infections and no history of breastfeeding.In clinical work，parents should be educated about public science，pay attention to breastfeeding，avoid recurrent respiratory infections，and actively receive treatment for allergic rhinitis in order to prevent the occurrence of CVA in children.

Key words:

Cough variant asthma, Pathogenic factor, Logistic regression, Child