关键词:

过敏性紫癜, 数据挖掘, 湿热证, 处方用药规律, 关联规则

Abstract:

Objective To analyze the law of traditional Chinese medicine prescription for damp-heat allergic purpura.Methods The Chinese Journal Full-text database，VIP database and Wanfang database were searched for literature related to Chinese medicine treatment for damp-heat allergic purpura.The data were processed and the database was established.The frequency analysis，association rule analysis and cluster analysis were carried out by using Excel 2019，SPSS modeler 18.0 and SPSS statistics 22.0.Results A total of 101 prescriptions were screened，involving 159 Chinese medicines and 22 high-frequency Chinese medicines，mainly including coix seed，Phellodendron amurense and Atractylodes macrocephala.The medicines were mainly cold，and the medicines were mostly bitter，sweet or pungent.The medicines functioned mainly through liver，lung，spleen and stomach meridians.The results of association rules showed that coix seed，Cortex phellodendri，Atractylodes lancea，Achyranthes bidentata，Arnebia，peony bark，madder and white grass root were closely related.Five clusters were obtained by cluster analysis. Conclusion The clinical treatment for damp heat syndrome of Henoch-Schnlein purpura mainly focus on the pathological factors such as "dampness"，"heat" and "blood stasis".The prescriptions reflect the characteristics of "clearing heat and dampness and removing blood stasis and hemostasis".The "Simiao pill" is commonly used to add and subtract the main formula of clearing heat and dampness，and flexible combination with "activating blood and removing blood stasis" can remove damp heat，eliminate blood stasis and restore healthy qi，and the disease is cured.

Key words:

Allergic purpura, Data mining, Damp heat syndrome, Law of prescription, Association rules