关键词: 脓毒症, 血液净化, 儿童

Abstract: Blood purification is an important adjunctive therapy for pediatric sepsis.Continuous blood purification(CBP) and plasma exchange(PE) are commonly used models in the treatment of pediatric sepsis.The efficacy of PE in the treatment of sepsis in children is currently not supported by large randomized controlled studies.CBP has the advantages of preventing and treating fluid overload,stabilizing hemodynamics,and continuously replacing or protecting damaged organs,so it is often used as the adjuvant therapy for septic shock and sepsis-associated organ dysfunction(SAOD) in children.High-volume hemofiltration is not recommended for CBP dosage,but there is no consensus on the timing of CBP intervention.In this paper,the research progress in CBP in treating sepsis in children was discussed.

Key words:

Sepsis, Blood purification, Children