ISSN 1674-3865  CN 21-1569/R
主管:国家卫生健康委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

中国中西医结合儿科学 ›› 2022, Vol. 14 ›› Issue (1): 25-28.

• 综述 • 上一篇    下一篇

人乳低聚糖与婴幼儿肠道健康研究进展

  

  • 出版日期:2022-02-25 上线日期:2023-12-05

Research progress on human milk oligosaccharides and intestinal health of infants

  • Published:2022-02-25 Online:2023-12-05

摘要: 母乳中的低聚糖通过调节肠道内微生物菌群构成、抵御致病菌群对肠黏膜上皮细胞入侵及调控机体免疫反应等生理作用,维持婴幼儿肠道健康,并且对于一些肠道功能紊乱的疾病,如坏死性小肠结肠炎、腹泻等,也可有效预防及治疗。本文主要阐述近年来国内外有关人乳低聚糖与婴幼儿肠道健康方面的研究进展,进一步探讨人乳低聚糖与婴幼儿肠道健康的相关性,为更好指导母乳喂养,预防和治疗相关疾病提供依据。

关键词: 人乳低聚糖, 生理作用, 坏死性小肠结肠炎, 婴幼儿腹泻

Abstract: Oligosaccharides in breast milk maintain the intestinal health of infants and infants by influencing the composition of the microbial flora in the intestine,resisting the invasion of pathogenic bacteria to intestinal mucosal epithelial cells,and regulating the immune response of the body.Some disordered intestinal diseases,such as necrotizing enterocolitis and diarrhea,can also be effectively prevented and treated.This article mainly describes the research progress on human milk oligosaccharides and infant intestinal health both at home and abroad in recent years,and further explores the correlation between human milk oligosaccharides and infant intestinal health,intending to better guide breastfeeding and provide evidence for the treatment and prevention of related diseases.

Key words: Human milk oligosaccharides, Physiological effects, Necrotizing enterocolitis, Infant diarrhea