关键词:

附子, 数据挖掘, 关联规则

Abstract:

ObjectiveTo explore the medication rule of famous veteran doctor of TCM-Zhao Kun-in prescription containing Aconiti lateralis radix praeparata.MethodsBased on the establishment of prescription database, the method of association rules was used to analyze the following items in the prescriptions containing Aconiti laterlis radix praeparata, including the frequency of single drug, frequency of drug combination, the association rules and the core drug combinations.ResultsThe prescriptions containing Aconiti lateralis radix praeparata were commonly used for treating asthma, cough and common cold. The drugs with highest frequency were Aconiti lateralis radix praeparata, Ephedrae herba, Farfarae flos, Houttuynia cordata thunb, Armeniacae semen amarum, Phragmitis rhizoma, Gypsum fibrosum and so on. The drug combinations with highest frequency were 'Aconiti lateralis radix praeparata and Ephedrae herba', 'Aconiti lateralis radix praeparata and Paeoniae radix rubra', and 'Aconiti lateralis radix praeparata and Pseudostellariae radix'. The drug association rules with the confidence being more than 0.9 were 'Aconiti lateralis radix praeparata→Ephedrae herba','Aconiti lateralis radix praeparata→Farfarae flos', 'Paeoniae radix rubra→Aconiti lateralis radix praeparata', and'Paeoniae radix alba→Ephedrae herba, Aconiti lateralis radix praeparata', and so on. The core drug combinations of association rules for treating asthma, cough and common cold had some similarities to Mahuang Fuzi Xixin decoction and Xiaoqinglong decoction.ConclusionThe prescriptions containing Aconiti lateralis radix praeparata developed by Pro. Zhao are widely used in pediatric pulmonary disease syndrome. The prescription medication is more concentrated, and the combination method is clear.

Key words:

Aconiti lateralis radix praeparata, Data mining, Association rules