关键词: IgA血管炎；器官；组织；合并症；回顾性研究；儿童 

Abstract: Objective To improve the understanding of IgA vasculitis and the level of diagnosis and treatment by analyzing its clinical characteristics in children.Methods Retrospectively analyze the clinical characteristics,auxiliary examinations,treatment and prognosis of the 5 children with IgA vasculitis admitted to the Department of Pediatrics of the First Affiliated Hospital of Henan University of Chinese Medicine from April 2018 to April 2021.Results There were 4 males and 1 female in 5 cases of IgA vasculitis.The median age was 6.There was 1 case of lung damage,1 case of liver damage,1 case of spleen damage,1 case of intestinal damage and 1 case of epididymis damage.During the course of the disease,4 cases had abdominal pain and 2 cases had joint pain.All children had typical skin purpura.There were 2 cases without abnormalities in urine testing and 3 cases with abnormalities in urine testing,including 1 case of simple proteinuria and 2 cases of hematuria and proteinuria.All children were improved after treatment with integrated traditional Chinese and Western medicine.Conclusion IgA vasculitis is the most common vascular inflammatory disease dominated by IgA deposition in childhood.In addition to purpura,abdominal pain and joint swelling and pain are the most common clinical manifestations.The disease is very likely to combine other organ damage and it′s even life-threatening,such as severe lung injury.When patients have other systemic symptoms,relevant examinations should be completed in time to clarify the condition and to avoid treatment delay.

Key words: IgA vasculitis, organ, organization, complication, a retrospective study, children