关键词: 单纯性肥胖, 炎症, 内质网应激, 巨噬细胞极化, 中西医治疗

Abstract: Simple obesity refers to the fact that the body′s intake of energy is greater than the consumption of energy,which is accumulated in the body in the form of fat,resulting in the main clinical manifestation of obesity,and it can be accompanied by abnormal metabolism of glucose and lipid and endocrine disorders.Its incidence is increasing year by year,and it has become a serious social public health problem.Simple obesity is a chronic low-grade inflammatory state,and its mechanism is closely related to endoplasmic reticulum stress,mitochondrial dysfunction,oxidative stress,and macrophage polarisation in the body.For this disease,both Chinese medicine and western medicine have their intervention and treatment means,but modern medicine believes that the treatment for obesity is a combination of dietary and nutritional structural adjustment,exercise,psycho-psychological and medication,which requires a high level of execution and compliance of the patient,and the medication also has obvious side effects.Chinese medicine has a unique theoretical understanding of obesity,and Chinese medicine treatment also has its unique advantages.In this paper,we will make a review of the mechanism of adipose tissue inflammation in simple obesity and the current status of Chinese and western medicine treatment.

Key words:

Simple obesity, Inflammation, Endoplasmic reticulum stress, Macrophage polarisation, Chinese and western medicine treatment