ISSN 1674-3865  CN 21-1569/R
主管:国家卫生健康委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

中国中西医结合儿科学 ›› 2025, Vol. 17 ›› Issue (1): 17-22.doi: 10.20274/j.cnki.issn.1674-3865.2025.01.004

• 儿童内分泌疾病专栏 • 上一篇    下一篇

饮食结构对儿童性早熟的影响研究现状

刘子琦,张桂菊   

  1. 250000 济南,山东中医药大学第一临床医学院2024级中医儿科学专业研究生(刘子琦);山东中医药大学附属医院儿科(张桂菊)
  • 收稿日期:2024-10-01 修回日期:2024-11-25 出版日期:2025-02-25 上线日期:2025-02-25
  • 通讯作者: 张桂菊,E-mail:13685316296@163.com
  • 基金资助:
    山东省自然科学基金项目(ZR2023QH158)

Current research status of the influence of dietary patterns on precocious puberty in children

LIU Ziqi1,ZHANG Guiju2   

  1. 1Shandong University of Traditional Chinese Medicine,Jinan 250000,China; 2Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan 250000,China
  • Received:2024-10-01 Revised:2024-11-25 Published:2025-02-25 Online:2025-02-25
  • Contact: ZHANG Guiju,E-mail:13685316296@163.com
  • Supported by:
    Shandong Province Natural Science Foundation Project(No.ZR2023QH158)

摘要: 当儿童在步入青春期阶段,会出现以生殖器官的形态、功能发育和第二性征发育为主的突出变化。性早熟的主要表现为第二性征提前发育,性器官提早成熟,属于一种儿童生长发育异常的内分泌疾病。随着经济社会的发展,性早熟发病年龄的提前和发病率的上升,使得社会关注度愈高。多种因素会对性早熟产生影响,现代研究证实青春期发育前的儿童日常饮食与性早熟存在关联。本文回顾了常见的儿童饮食模式及各类膳食营养成分与青春期性发育相关的国内外文献,以高热量饮食模式、地中海饮食模式和素食模式为代表,综述了不同饮食结构对儿童性早熟的影响作用,分别对高热量饮食模式中的高蛋白饮食、高脂饮食、高糖饮食以及地中海饮食模式和素食模式中的主要膳食成分(蔬菜、水果、橄榄油、谷物、坚果、豆类及乳制品)在性发育中发挥调控的潜在机制进行了归纳与总结,旨在从饮食干预方面为儿童性早熟的预防和治疗提供理论依据,为膳食营养结构与性发育相关的未来研究提供新的思路。

关键词: 性早熟, 饮食结构, 营养, 饮食模式, 青春期, 儿童

Abstract: When children enter puberty,they will experience prominent changes mainly in the morphology of their reproductive organs,and development of function and secondary sexual characteristics.The main manifestation of precocious puberty is the earlier development of secondary sexual characteristics and the premature maturation of sexual organs,which is an endocrine disease characterized by abnormal growth and development of children.With the development of economy and society,the advancement of the onset age of precocious puberty and the increase in incidence rate have triggered increasing social attention.Multiple factors can have an impact on precocious puberty,and modern researches have confirmed a correlation between the daily diet of children before puberty and precocious puberty.This article reviews domestic and foreign researches in common dietary patterns and various dietary nutrients related to adolescent sexual development in children,represented by high calorie diet patterns,Mediterranean diet patterns,and vegetarian diet patterns,and it summarizes the influence of different dietary patterns on precocious puberty in children.The article respectively summarizes the potential regulatory mechanisms of high protein diet,high-fat diet and high sugar diet in high calorie diet patterns,as well as the main dietary components (vegetables,fruits,olive oil,grains,nuts,beans,and dairy products) in Mediterranean diet patterns and vegetarian diet patterns in sexual development.The aim is to provide theoretical basis for the prevention and treatment of precocious puberty in children from the perspective of dietary intervention,and to provide new ideas for future researches on the relationship between dietary nutrition structure and sexual development.

Key words: Precocious puberty, Dietary structure, Nutrition, Dietary patterns, Adolescence, Child