祛风止动贴治疗中度抽动障碍的随机对照临床研究

doi:10.3969/j.issn.1674-3865.2023.05.005

Abstract

Abstract: Objective To evaluate the clinical effect of Qufeng Zhidong plaster in the treatment of moderate tic disorder. Methods From January 2021 to December 2022, 140 children were evaluated as moderate tic disorder in the tic disorder specialist clinic and the traditional Chinese medicine pediatric clinic of Xinhua Hospital affiliated to Shanghai Jiao Tong University School of Medicine, and were randomly divided into the observation group and the control group, with 70 cases in each group. All patients were treated with Qufeng Zhidong formula. On this basis, Qufeng Zhidong plaster was used in the observation group and blank simulated plaster was used in the control group. After 3 months of treatment, the clinical efficacy and TCM syndrome score of the two groups were evaluated. Results Five cases were removed from the observation group and 8 cases were removed from the control group. At 12 weeks after treatment, there was no statistical difference in the incidence of adverse reactions between the observation group and control group (P>0.05), and the total clinical effective rate of the observation group was 95.38% (62/65), which was higher than that of the control group (83.87%,52/62), and the difference was statistically significant (P<0.05). The YGTSS score of children with tic disorder was improved by both treatment methods. The treatment of Qufeng Zhidong plaster plus Qufeng Zhidong formula was better than that of simulated plaster plus Qufeng Zhidong formula, and the difference was statistically significant (P<0.05). After 12 weeks of treatment, the total efficacy score of the observation group was lower than that of the control group, and the efficacy index score was higher than that of the control group, the difference being with statistical significance (P<0.05). The TCM syndrome score of the observation group was lower than that of the control group at 8 weeks and 12 weeks after treatment, and the difference was statistically significant(P<0.05). Conclusion Qufeng Zhidong plaster combined with Chinese medicine is effective in the treatment of moderate tic disorder, and can significantly improve the clinical symptoms and TCM syndromes of patients.

Key words:

Tic disorder, Qufeng Zhidong plaster, Clinical efficacy evaluation

GAO Yuan, WU Min, JIANG Keyu, ZHANG Xin, ZHAO Xin. A randomized controlled clinical study on the treatment of moderate tic disorder with Qufeng Zhidong plaster[J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2023, 15(5): 388-392.

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A randomized controlled clinical study on the treatment of moderate tic disorder with Qufeng Zhidong plaster

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