Abstract: Functional constipation in children is a common disease in pediatrics,which is mainly manifested as difficulty in defecation,reduced frequency of defecation and/or prolonged defecation.The incidence and recurrence rate of this disease is relatively high,and at the same time,functional constipation seriously affects the quality of life of children,which is unfavorable to the growth and development of children.In recent years,with the increase of social pressure,the incidence of this disease has been increasing year by year;in addition to physical symptoms,children′s mental symptoms also gradually gain concern,and very often functional constipation is accompanied by abnormal emotional symptoms in children.The mechanism of functional constipation is mainly "abnormal interaction between the brain and intestines" as proposed in Rome Ⅳ,which is also related to the holistic concept of "five organs as one" and the theoretical view of form and spirit being all as one in Chinese medicine,so this article takes the theory of "brain-intestine correlation" and the "brain-intestine axis" in modern medicine as the entry point to make an in-depth analysis of the doctrine of "brain-intestine correlation".Based on the special connection between the brain and the intestine,which are physiologically related to each other and pathologically influenced by each other,we believe that the treatment for functional constipation should not only regulate the gastrointestinal function to improve intestinal symptoms,but also pay attention to the role of the heart and brain in regulating the spirit to improve the patient′s anxiety,depression and other mental symptoms,and explore the treatment method of regulating the spirit to achieve the effect of intestinal transport,aiming to find a new way of thinking about the treatment for functional constipation,and provide a new method to improve the quality of life of children with functional constipation.

Key words:

Functional constipation, Brain-intestine correlation, Brain-gut axis, Children