Abstract: Objective To explore the effect of late-onset breast milk jaundice on the myocardial cells of affected children and the clinical value of early intervention treatment.Methods A retrospective review of 86 cases of late-onset breast milk jaundice admitted to our Pediatric Center from April 2020 to January 2022 was conducted.According to the bilirubin level,they were divided into mild and moderate-severe groups.Sixty full-term healthy newborns examined in the Children's Health Clinic of our hospital during the same period were selected as the control group.On the day of admission,blood samples were collected from the study group during the peak and subsidence periods of jaundice,and 2 to 3 mL of venous blood was taken to detect serum totalwere higher than those in the mild group and the control group,with statistically significant differences(P<0.05).There was no statistically significant difference in the levels of myocardial enzymes(CK,CK-MB) and cTnI between the mild group and the control group(P>0.05).During the subsidence period of jaundice,there was no statistically significant difference in the levels of myocardial enzymes(CK,CK-MB) and cTnI between the mild and moderate-severe groups and the control group(P>0.05).During the peak period of jaundice in the moderate-severe group,the detection rate of cTnI was 51.4%(18/35),which was significantly higher than the detection rates of CK and CK-MB［17.1%(6/35),25.7%(9/35)］,with statistically significant differences(P<0.05).Conclusion Detecting serum myocardial enzymes(CK,CK-MB) and cTnI can early identify myocardial damage in children with late-onset breast milk jaundice.The higher the serum bilirubin level,the more severe the myocardial damage,indicating that early intervention and treatment has certain clinical value. bilirubin,myocardial enzymes (CK,CK-MB),and cardiac troponin I (cTnI).The control group underwent routine testing of the above items,and the results were statistically analyzed.ResultsDuring the peak period of jaundice,the levels of myocardial enzymes(CK,CK-MB) and cTnI in the moderate-severe group 

Key words:

Late-onset breast milk jaundice, Myocardial damage, Myocardial enzyme profile, Cardiac troponin I