Abstract: Autism spectrum disorders(ASD) is characterized by sustained impaired social ability, repetitive behaviors or interests, and stereotyped behavior. It is a common pediatric neuropsychiatric disease with great harm in TCM pediatrics, and in 2020, the domestic incidence has reached 7‰. The optimal treatment period is often missed due to delayed diagnosis, limited treatment measures, failure to adhere to treatment, improper parental care and so on. The "Original Spirit" of ASD is damaged, and the lesion is in the brain. This paper analyzes the correlation between brain and spleen and kidney from the material basis, structural basis, operational basis and pathological connection, and concludes that the deficiency of spleen and kidney is the fundamental pathogenesis of ASD, and phlegm and blood stasis is the important pathological factors of ASD. Professor Wang Junhong thinks that the physiological and pathological characteristics of children should be considered clinically, and the basic treatment should be to tonify the kidney and spleen, eliminate phlegm and remove blood stasis. At the same time, there should be no improper tonification, and the focus is to regulate the whole body movement and chemical function of children. In the treatment, the classic prescription Liuwei Dihuang pills and Liujunzi decoction are selected as the main prescription of Bushen Yunpi Yizhi prescription. According to the viscus syndrome, the treatment combines comprehensive analysis of the four examination methods and achieves good effects. Based on clinical cases, this article introduces the key points of syndrome differentiation, treatment and medication experience of Bushen Yunpi Yizhi prescription in the treatment of children with ASD.

Key words: Autism spectrum disorders, Brain and spleen and kidney, Bushen Yunpi Yizhi ,

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