ISSN 1674-3865  CN 21-1569/R
主管:国家卫生和计划生育委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

Chinese Pediatrics of Integrated Traditional and Western Medicine ›› 2024, Vol. 16 ›› Issue (2): 130-136.doi: 10.3969/j.issn.1674-3865.2024.02.007

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Risk prediction of attention deficit hyperactivity disorder based on machine learning

ZHAO Jianxiang, WU Zhenqi, WANG Xuefeng, WANG Zi, CHU Yaqi, YOU Yi   

  1. The Liaoning University of TCM,Shenyang 110847,China
  • Received:2023-02-08 Published:2024-04-25 Online:2024-04-25
  • Contact: WU Zhenqi,E-mail:zhenqiwu@163.com

Abstract: Objective To explore the feasibility of predicting attention deficit hyperactivity disorder(ADHD) in children based on machine learning algorithm.Methods A total of 358 patients treated in the pediatric outpatient department of our hospital from November 2022 to August 2023 were retrospectively analyzed,and 119 patients were finally included in the ADHD group and 239 patients in the non-ADHD group.Totally 31 variables,including basic demographic information,children's personal life situation,mother's pregnancy situation,family life situation and genetic factors,were taken as risk factors.Single factor analysis was used to select variables with obvious differences,and then the decision tree(DT) model,random forest(RF) model,adaptive enhancement algorithm(Adaboost) and K-nearest neighbor algorithm(KNN) models were established respectively.AUC,specificity,accuracy,F1 score and ROC curve were used to evaluate the model prediction efficiency.Results Random forest algorithm was the best predictive model for ADHD,with AUC being 0.955,and specificity,accuracy and F1 scores being 0.903,0.898 and 0.853,respectively.Meanwhile,the top five characteristic variables screened according to the random forest model were:education style,emotional stability,daily time spent playing with electronic products,learning difficulties,and recent recurrent respiratory infections.Conclusion A prediction model of child ADHD based on machine learning algorithm is established,which has good prediction ability for ADHD.

Key words:

Attention deficit hyperactivity disorder, Risk factors, Machine learning, Prediction model, Children