Abstract: ObjectiveTo explore the clinical efficacy of Xiaoer Kechuanling oral solution (concentrated) in the treatment of children with Mycoplasma pneumoniae pneumonia and the changes in inflammatory factor levels.MethodsTotally 110 children with Mycoplasma pneumoniae pneumonia who received treatment in the Pediatric Department of Liaoning University of Traditional Chinese Medicine Affiliated Hospital were selected as the research subjects. Using a random number table method, they were divided into an observation group and a control group, with 55 cases in each group. All patients received basic western medicine treatment, and the observation group received combined treatment with Xiaoer Kechuanling oral solution (concentrated) additionally. Compare the clinical efficacy, symptom improvement time, time of pulmonary rales disappearing, levels of inflammatory factors, and incidence of adverse reactions during treatment between the two groups of children.ResultsThe total effective rate of the observation group(94.55%, 52/55) was higher than that of the control group(81.82%, 45/55)(P<0.05). The duration of fever, cough, expectoration, and pulmonary rales in the observation group was significantly shorter than that in the control group (P<0.05). There was no statistical difference in the improvement of the levels of tumor necrosis factor alpha(TNF-α) in these children between the two treatment regimens(P>0.05), while there was statistical difference in the improvement of IL-6 levels between the two treatment regimens (P<0.05). There was no statistically significant difference in the incidence of adverse reactions between the two groups during the treatment period (P>0.05).ConclusionOn the basis of western medicine treatment, the application of Xiaoer Kechuanling oral solution (concentrated) can effectively improve the clinical efficacy in the treatment of Mycoplasma pneumoniae pneumonia in children, shorten the duration of fever, cough, expectoration and lung rales and inhibit inflammatory reactions, and it is quite safe.

Key words: Mycoplasma pneumoniae pneumonia, Xiaoer Kechuanling oral solution(concentrated type), Clinical efficacy, Child