Abstract:
Kawasaki disease(KD)is an acute systemic vasculitis mainly affecting infants and children under 5 years old.Coronary artery lesions(CALs)are the most serious complication.KD is liable to be complicated by coronary artery lesion(CAL)in approximately 25% of untreated KD children.In the acute phase，high dose of intravenous immunoglobulin(IVIG)can relieve symptoms quickly and significantly reduce the risk of CAL.Some adjunctive therapies,including glucocorticoids and infliximab，have been used in treatment of IVIG resistant KD over the past few years.This article also introduces the treatment and management of KD after the acute phase.

Key words: Kawasaki disease, Coronary artery lesion, Gamma globulin, Treatment, Later management, Children