Abstract:
Objective:To observe the clinical effect of the treatment for pediatric Mycoplasma pneumoniae infection cough by integrated medicine staging therapies.
Methods:Select 120 cases of children with Mycoplasma pneumoniae infection and they were divided into Chinese medicine treatment group(group A),Western medicine treatment group(group B),and the combination therapy group(group C),40 patients in each group.Group A received Chinese medicine for the staging treatment;group B was given azithromycin therapy;group C was given azithromycin combined with Chinese medicine staging therapy.Three groups of children had a treatment course of 7 days,totally four courses of treatment,and then were followed up for two months after treatment.After 7 days,14 days and 28 days of treatment,respectively,observe the cough and expectoration scores,the improvement in major and minor symptom scores;observe the negative-conversion rate of MP-IgM after treatment and at 2 months of follow-up;observe the clinical effect in the 3 groups.
Results:(1)Comparison of the effect before and after treatment:after 7 d of treatment,the total effective rate of Group C was higher than that of Group A and B,the difference being statistical(P<0017),but there was no statistical difference between Group B and C(P<0017);after 14 d of treatment,the total effective rate of Group C was higher than that of Group C(P<0017),but there was no statistical difference between Group A and Group B and C(P>0017).After 28 d of treatment,there was no statistical difference in the effect among the 3 groups(P>005).(2)Comparison of negative-conversion rate of MP-IgM:there was no statistical difference among the 3 groups after treatment(P>005);at 2 months of follow-up,the difference in the rate was statistical among the 3 groups(P<005),which was higher in Group C(P<0017),but no statistical difference was shown between Group A and B(P>0017).
Conclusion:In terms of improving clinical symptoms and signs,the treatment with azithromycin combined with Chinese staging treatment is effective for children with Mycoplasma pneumoniae infection cough,and is better than the use of either of them alone.The mid-term effect of Chinese staging treatment is better than that of azithromycine,but no difference is observed in the early and late period of the treatment.

Key words: Mycoplasma pneumoniae infection, Coug, Integrative Chinese and western medicine treatment, Children