Abstract:
Objective:To investigate the effect of compound glycyrrhizin injection in the treatment of children with pneumonia and liver dysfunction.
Methods:From January 2014 to May 2015 in Women and Children Hospital in Jiyuan city,60 children admitted to the hospital for pneumonia and liver dysfunction were randomly divided into two groups:the observation group and the control group.Two groups were both given anti-infection and inhalation therapy to treat pneumonia.The observation group was given compound glycyrrhizin injection to cure liver dysfunction,while the control group was given glucurolactone injection.
Results:The total effective rate of observation group was 967%(29/30),significantly higher than the total effective rate of control group［733%(22/30)］,the difference being statistically significant(P<005).The total course of the observation group was(568±121)d,significantly shorter than the control group(922±098)d,the difference being statistically significant(P<005).The result of blood,urine and kidney function of two groups during treatment was in the normal range,with no significant adverse reactions.
Conclusion:The compound glycyrrhizin injection combined with antibacterial drugs and inhalation treatment for children with pneumonia and liver dysfunction has good effect,which can not only accelerate the improvement of pneumonia,but also promote the recovery of liver function.

Key words: Pneumonia, Liver dysfunction, Compound glycyrrhizin injection, Glucurolactone, Children