Abstract:
Objective
To observe the curative effect of Xiyanping injection in the treatment of Mycoplasma pneumoniae pneumonia in children.
Methods
The data of 571 cases of children with Mycoplasma pneumoniae pneumonia were reviewed, who were treated from Jan. 1,2012 to Dec. 31,2016 in Department of Pediatrics， Central Hospital Affiliated to Shenyang Medical College. The 571 cases of children with Mycoplasma pneumoniae pneumonia were divided into treatment group(n=278) and control group(n=293). Both groups were given conventional treatment of relieving cough, removing sputum, relieving asthma, supplementing liquid and inhaling oxygen. The control group was treated with erythromycin injection by intravenous dripping, twice a day. The observation group received intravenous dripping of Xiyanping injection in addition to the erythromycin, once a day. Both groups were treated for 7 days as a course. Observe the clinical effect and the time for symptoms and signs to improve in the two groups.
Results
The effect of the observation group was better than that of the control group, the difference being statistical(Z=-3.94,P<0.05). The cure rate of observation group was 70.86% (197/278), significantly higher than that of control group(54.94%, 161/293)，and there was statistical difference(P<0.05). The time of fever disappearance, cough relief and the disappearance of lung rales was shorter in observation group than that in control group, and the difference was statistically significant(P<0.01).
Conclusion
Xiyanping injection has good effect in the treatment of children with Mycoplasma pneumoniae pneumonia, which combined with antibiotic, can help to relieve the clinical symptoms and signs, deserving clinical application.

Key words: Pneumonia, Mycoplasma pneumoniae, Erythromycin, Xiyanping, Children