Table of Content

25 April 2016, Volume 8 Issue 2 Previous Issue    Next Issue

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Diagnosis and differential diagnosis of Kawasaki disease LI Bo，ZHANG Xuguang 2016, 8 (2):  125-128.  doi: 10.3969/j.issn.1674-3865.2016.02.001 Abstract ( 773 )   PDF (529KB) ( 158 )   Save Kawasaki disease(KD)is characterized by acute systemic vasculitis，which may lead to serious cardiovascular complications.At present，KD has become one of the most common reasons for acquired heart disease in children.However,the cause of KD is still unknown,and KD lacks specific clinical manifestation and the authoritative laboratory indexes.Correct diagnosis and differential diagnosis play a key role in standardized treatment to reduce cardiovascular injury.This article reviews the recent advance in the methods of diagnosis and differential diagnosis of KD. Related Articles | Metrics

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Diagnosis and treatment of incomplete Kawasaki disease SUN Jinghui，XU Yang 2016, 8 (2):  128-131.  doi: 10.3969/j.issn.1674-3865.2016.02.002 Abstract ( 446 )   PDF (427KB) ( 119 )   Save To date，the etiology of Kawasaki disease(KD)remains unclear and no definite diagnostic test exists.The diagnosis is mainly based on its clinical features.However，pediatricians always encounter febrile children who do not fulfill the diagnostic criteria but have several findings similar to those of Kawasaki disease，and these children are said to have incomplete KD.The two diseases have similar epidemiological features，clinical presentations，laboratory profiles and treatment methods.Owing to the absence of some major criteria，incomplete KD can easily be misdiagnosed,resulting in a delayed treatment，which in turn can lead to the development of coronary artery lesions(CALs).More timely diagnosis and treatment of incomplete KD patients can improve the prognosis. Related Articles | Metrics

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Precise treatment for Kawasaki disease SUN Le，LI Xuemei，YU Xianyi 2016, 8 (2):  132-135.  doi: 10.3969/j.issn.1674-3865.2016.02.003 Abstract ( 396 )   PDF (502KB) ( 138 )   Save Kawasaki disease(KD)is an acute systemic vasculitis mainly affecting infants and children under 5 years old.Coronary artery lesions(CALs)are the most serious complication.KD is liable to be complicated by coronary artery lesion(CAL)in approximately 25% of untreated KD children.In the acute phase，high dose of intravenous immunoglobulin(IVIG)can relieve symptoms quickly and significantly reduce the risk of CAL.Some adjunctive therapies,including glucocorticoids and infliximab，have been used in treatment of IVIG resistant KD over the past few years.This article also introduces the treatment and management of KD after the acute phase. Related Articles | Metrics

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Effect of Qingfei Tongluo ointment on the PI3K/Akt/NF-kappaB signaling in rats infected with RSV LIU Xiaoxue,WANG Xuefeng,ZHANG Xiuying,WANG Yihuan,WANG Siyuan,NAN Chunhong 2016, 8 (2):  136-138.  doi: 10.3969/j.issn.1674-3865.2016.02.004 Abstract ( 395 )   PDF (394KB) ( 140 )   Save Objective:To observe the effect and the mechanism of Qingfei Tongluo ointment on the expression of PI3K,AKT1/2 and NF-κB p65 in rats infected with RSV. Methods:Totally 30 rats were randomized into 3 groups,namely,normal group,model group,treatment group,with 10 rats in each.The rats of the last two groups were made into RSV infection models.For treatment group Qingfei Tongluo ointment was given at the first day of the experiment,once daily for seven consecutive days.Examine the levels of PI3K,AKT1/2 and NF-κB p65 in lung tissue,using the method of immunohistochemistry. Results:The result of PI3K,AKT1/2 and NF-κB p65 expression in lung tissue showed that：compared with the normal group，the model group had significant difference(P<005);compared with the model group，the treatment group had significant difference（P<005）. Conclusion:Qingfei Tongluo ointment is an effective drug for external use in RSV infection;its action mechanism may be through adjusting the PI3K/Akt/NF-κB signaling. Related Articles | Metrics

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Clinical study of children with Mycoplasma pneumoniae infection cough treated by integrated medicine staging therapies YU Minfeng，CHEN Xianjun 2016, 8 (2):  139-143.  doi: 10.3969/j.issn.1674-3865.2016.02.005 Abstract ( 277 )   PDF (465KB) ( 90 )   Save Objective:To observe the clinical effect of the treatment for pediatric Mycoplasma pneumoniae infection cough by integrated medicine staging therapies. Methods:Select 120 cases of children with Mycoplasma pneumoniae infection and they were divided into Chinese medicine treatment group(group A),Western medicine treatment group(group B),and the combination therapy group(group C),40 patients in each group.Group A received Chinese medicine for the staging treatment;group B was given azithromycin therapy;group C was given azithromycin combined with Chinese medicine staging therapy.Three groups of children had a treatment course of 7 days,totally four courses of treatment,and then were followed up for two months after treatment.After 7 days,14 days and 28 days of treatment,respectively,observe the cough and expectoration scores,the improvement in major and minor symptom scores;observe the negative-conversion rate of MP-IgM after treatment and at 2 months of follow-up;observe the clinical effect in the 3 groups. Results:(1)Comparison of the effect before and after treatment:after 7 d of treatment,the total effective rate of Group C was higher than that of Group A and B,the difference being statistical(P<0017),but there was no statistical difference between Group B and C(P<0017);after 14 d of treatment,the total effective rate of Group C was higher than that of Group C(P<0017),but there was no statistical difference between Group A and Group B and C(P>0017).After 28 d of treatment,there was no statistical difference in the effect among the 3 groups(P>005).(2)Comparison of negative-conversion rate of MP-IgM:there was no statistical difference among the 3 groups after treatment(P>005);at 2 months of follow-up,the difference in the rate was statistical among the 3 groups(P<005),which was higher in Group C(P<0017),but no statistical difference was shown between Group A and B(P>0017). Conclusion:In terms of improving clinical symptoms and signs,the treatment with azithromycin combined with Chinese staging treatment is effective for children with Mycoplasma pneumoniae infection cough,and is better than the use of either of them alone.The mid-term effect of Chinese staging treatment is better than that of azithromycine,but no difference is observed in the early and late period of the treatment. Related Articles | Metrics

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Effect of motor imagery therapy on the upper limb function of patients with hemiplegic cerebral palsy MENG Jing， LI Xiaojie， QIU Xia， LIU Chen，TANG Jinghua，TIAN Taorui 2016, 8 (2):  144-147.  doi: 10.3969/j.issn.1674-3865.2016.02.006 Abstract ( 285 )   PDF (488KB) ( 117 )   Save Objective:To study the effect of motor imagery(MI) therapy on the upper limb function of in patients with hemiplegic cerebral palsy. Methods:Twenty cases of hemiplegic cerebral palsy were randomly divided into the observation group and the control group，10 cases in each group.The observation group was given motor imagery therapy and routine rehabilitation training，while the patients in control group were treated with routine rehabilitation training.Before treatment and 10 weeks after treatment the scores were made on upper limb Peabody developmental scale，children′s functional independence rating(WeeFIM)，thickness of the biceps brachii and supination of the forearm angle.Observe the effect of motor imagery therapy on the function of upper limb of children with hemiplegic cerebral palsy. Results:After 10 weeks of treatment，hemiplegic limb Peabody fine motor score， children′s functional independence score， thickness of the biceps brachii， fore arm supination angles were increased in both groups(P<005);in observation group,Peabody fine motor score， children′s Functional Independence score,biceps brachii muscle thickness and fore arm supination angles were higher than those of the control group，the difference being statistically significant (P<005).Peabody fine motor score and biceps brachii muscle thickness had positive correlation(r=078， P<005). Conclusion:Motor imagery therapy helps to improve the upper limb motor function in children with hemiplegic cerebral palsy， and can increase the angle of forearm rotation and muscle thickness. Related Articles | Metrics

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Clinical study of combined therapy of traditional Chinese and western medicine in the treatment of infantile cholestatic liver disease XU Li,LIU Yali,WEI Kelun 2016, 8 (2):  148-151.  doi: 10.3969/j.issn.1674-3865.2016.02.007 Abstract ( 451 )   PDF (555KB) ( 111 )   Save Infantile cholestatic hepatopathy(ICH)is a common disease of the liver and gallbladder disease in infancy(including neonatal period),and the incidence of the disease is 1/2 500 ~ 1/5 000.If the patient is not relieved,the disease can accelerate the damage of the liver cells,and develop into liver fibrosis and cirrhosis with the progress of the disease.Therefore choosing effective drugs for early treatment is especially critical.Through analyzing the etiology,pathogenesis and clinical features of ICH， and exploring ICH treatment method of the present stage,this article analyzes the advantage of treatment of traditional Chinese medicine combined with western medicine,which not only lies in hepatoprotective,anti-inflammatory and immune mediation aspect,but also can increase the curative effect and improve the prognosis. Related Articles | Metrics

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Research progress of TCM external treatment for children with bronchiolitis WU Mingyun,HOU Jianghong 2016, 8 (2):  151-153.  doi: 10.3969/j.issn.1674-3865.2016.02.008 Abstract ( 490 )   PDF (459KB) ( 162 )   Save To investigate the research progress of external therapy of TCM for child bronchiolitis.In Western medicine,excessive use of antibiotics will reduce the immunity of children.External therapy of TCM,such as massage,acupuncture,patching,cupping,enema,medicated bathing,percutaneous administration and acupoint-injection,play an important role in the treatment of children with bronchiolitis,which partly makes up for the disadvantage of oral administration of traditional Chinese medicine and Western medicine. Related Articles | Metrics

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Effect of intravenous anesthesia combined with sacral canal block on cardiac and renal function of neonates XIE Qiumei 2016, 8 (2):  154-157.  doi: 10.3969/j.issn.1674-3865.2016.02.009 Abstract ( 506 )   PDF (516KB) ( 99 )   Save Objective:To analyze the effect of intravenous anesthesia combined with sacral canal block on the heart and kidney function in neonates. Methods:A total of 80 infants who received surgical treatment in our hospital from June 2013 to December 2014 were chosen as the research objects,and were assigned to the control group and the experiment group(with 40 in each).In the experiment group,the patients were treated with intravenous anesthesia combined with sacral canal block,and the control group was treated with intravenous inhalation anesthesia.The changes of cardiac and renal function were compared between the two groups. Results:(1)There was no significant difference in preoperative heart function index between the two groups(P>005).During the surgery,CVP,SBP,Tei,CIL,DBP and HR of the control group were significantly higher,which decreased after the surgery but remained higher than the preoperative level except Tei index(P<005).(2)There were no significant differences in renal function index(P>005)in the two groups before treatment,while during the surgery the Scr,NAG,BUN and RBP were significantly higher in the two groups(P<005),but the increase was lower in the experiment group than that in the control group(P<005).The NAG,RBP and Scr in the control group were not immediately restored after treatment(P<005).(3)The postoperative spontaneous breathing recovery time,waking time,awake time and extubation time in experiment group were significantly shorter than in control group(P<001),OAA/S score higher than the control group(P<005).There were no children with restlessness in experiment group,while there were 8 cases(40%)in the control group(P<001). Conclusion:Intravenous anesthesia combined with sacral canal block has an ideal anesthetic effect,which can reduce the stress reaction of heart in neonates while shows no significant effect on kidney. Related Articles | Metrics

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Clinical study on Kechuanling effervescent tablets in treatment of children with pneumonia ZHANG Xiuying，HU Ling，ZHAO Guohua，JIANG Fengyuan 2016, 8 (2):  158-161.  doi: 10.3969/j.issn.1674-3865.2016.02.010 Abstract ( 425 )   PDF (462KB) ( 153 )   Save Objective:To evaluate the effects of Kechuanling effervescent tablets in treating children with pneumonia. Methods:A randomized controlled trial was used.Totally 188 cases of children with pneumonia were divided into observation group(93 cases) and the control group(95 cases).The observation group was given Kechuanling Effervescent Tablets combined with basic treatment,and the control group was treated only by basic treatment,then evaluate these two groups of children with the disease concerning overall curative effect,Chinese medicine syndrome efficacy,disappearance time of fever and cough effect and hospital days. Results:The observation group was better than the control group concerning the overall efficiency and effect on Chinese syndromes,the difference being statistical(P<005).The effect time and the disappearance time of cough,expectoration and lung roles was shorter in the observation group,and there was statistical difference(P<005). Conclusion:Kechuanling effervescent tablets has the effect of relieving cough,reducing sputum,promoting the absorption of lung roles and shortening the treatment course in the treatment of children with pneumonia. Related Articles | Metrics

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Expression significance of Daxx protein in bone marrow cells of children with acute leukemia FENG Jingqiao 2016, 8 (2):  161-163.  doi: 10.3969/j.issn.1674-3865.2016.02.011 Abstract ( 309 )   PDF (370KB) ( 110 )   Save Objective:To explore the expression significance of Daxx protein in bone marrow cells of children with acute leukemia. Methods:Totally 100 cases of children with acute leukemia were selected as the research object in this study from Feb.2010 to Oct.2014 in the First Affiliated Hospital of Shantou University Medical College and divided into 3 groups according to the type of disease,including acute lymphoblastic leukemia(ALL)group of 49 cases,acute non-lymphocytic leukemia(ANLL)group of 21 cases,acute myeloid leukemia(AML)group of 30 cases.The control group consisted of 30 cases,who were normal healthy children of the same age.The expression of Daxx protein was detected by immunohistochemical method. Results:The expression rate of Daxx protein in the control group(667%)was much smaller than that in ALL group(3038%),ANLL group(6667%)and AML group(4667%),the difference being statistically significant(P<005).Expression of Daxx protein in the control group in the bone marrow of children with acute leukemia(601±113)μg/L was significantly higher than that in ALL group(355±232)μg/L,ANLL group(354±247)μg/L and AML group(351±253)μg/L,the difference being statistically significant(P<005). Conclusion:The overexpression of Daxx protein in bone marrow cells of children with acute leukemia may play an important role in promoting the proliferation and growth of leukemia cells. Related Articles | Metrics

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An effect observation of treatment for severe paediatric viral myocarditis with Dushen decoction GAO Liang 2016, 8 (2):  164-166.  doi: 10.3969/j.issn.1674-3865.2016.02.012 Abstract ( 312 )   PDF (374KB) ( 96 )   Save Objective:Observe the clinical effects of treatment for severe paediatric viral myocarditis with Dushen decoction. Methods:We divided 16 children with severe viral myocarditis into the control group and the observation group.The control group was treated with western medicine,while the observation group was treated with conventional western medicine along with Dushen decoction.After two weeks of treatment,observe the clinical efficacy of the treatment on the above two groups,and the changes in troponin and creatine kinase isoenzyme. Results:The total effective rate was higher in the observation group than in the control group with statistical difference(P<005).Both the two groups have shown significant decrease in troponin and creatine kinase isoenzyme after treatment,with the observation group much lower than the control group,the difference being statistically significant(P<005).No adverse reaction occurred in both groups. Conclusion:The treatment for severe paediatric viral myocarditis with Dushen decoction can produce definite curative effects and is safer. Related Articles | Metrics

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Observation on the effect of different ways of inhalation for acute attack of bronchial asthma YANG Shihong 2016, 8 (2):  166-168.  doi: 10.3969/j.issn.1674-3865.2016.02.013 Abstract ( 276 )   PDF (391KB) ( 113 )   Save Objective:To compare the effect of two ways of inhalation in the treatment of children with acute attack of asthma. Methods:A total of 84 children with acute attack of bronchial asthma of moderate stage in Jingzhou Women and Children Hospital from Jan.2012 to Jan.2015 were included in the study and they were divided into two groups:observation group and control group,with 42 cases in each group.Salbutamol aerosol was put into spacer for inhalation for the observation group,while salbutamol solution was put into air-compression pump for nebulized inhalation in the control group.Compare the relief time,effect and adverse reactions between the two groups. Results:After 60 min of treatment,the total effective rate had no statistical difference between the two groups(P>005).Cough,wheezing and wheezing rales disappeared after treatment in both groups,the difference being of no statistical significance(P>005).There was one case of palpitation respectively in each group,but there was no other obvious adverse reaction. Conclusion:Both of the two ways of treatment mentioned above can rapidly relieve the clinical symptoms of patients with acute attack of asthma,therefore the medical institutions can choose either of them based on their own situations. Related Articles | Metrics

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Clinical observation on the effect of sea-buckthorn dry emulsion in the treatment of children with mesenteric lymphadenitis XIE Xiaoshu，ZHANG Huiyong 2016, 8 (2):  169-171.  doi: 10.3969/j.issn.1674-3865.2016.02.014 Abstract ( 1150 )   PDF (386KB) ( 112 )   Save Objective:To observe the clinical curative effect of sea-buckthorn dry emulsion in auxiliary treatment of pediatric mesenteric lymphadenitis. Methods:Select 120 cases of children diagnosed with mesenteric lymphadenitis，and they were randomly divided into control group and observation group,with 60 cases in each group.Control group was given amoxicillin clavulanic acid potassium dispersible tablets orally taken.Observation group was added sea-buckthorn dry emulsion.The course was 10 d.Observe clinical symptoms,signs,pain relief time and curative effect of two groups. Results:The curative rate of the observation group was 883%(53/60),which was significantly higher than that of the control group［517%(31/60)］,and the difference was statistically significant.In observation group pain relief time after treatment was(20±15)d,which was shorter than that of control group(30±13)d.The improvement in clinical symptoms and signs was better in observation group than in control group(P<005). Conclusion:The treatment with sea-buckthorn dry emulsion for pediatric mesenteric lymphadenitis is of significant effect,and it can effectively relieve clinical symptoms and signs of the disease,which is worthy of clinical popularization and application. Related Articles | Metrics

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Analysis of the clinical features and prognosis of 10 children with fulminant myocarditis manifested first with digestive symptoms YU Yajie 2016, 8 (2):  171-174.  doi: 10.3969/j.issn.1674-3865.2016.02.015 Abstract ( 290 )   PDF (1508KB) ( 144 )   Save Objective:To summarize the clinical features,treatment and prognosis of fulminant myocarditis manifested first with digestive symptoms. Methods:Ten children with fulminant myocarditis manifested first with digestive symptoms were admitted to the Second Hospital of Chaoyang from Aug.2004 to Aug.2014.The children had heart failure and cardiac shock.They were given breathing machine for assistant breathing,intravenous dripping with dopamine and dobutamine,001% adrenaline to strengthen heart,amiodarone to revert cardiac rhythm,and closed chest compression.Myocardial enzymes,troponin and blood glucose were determined,and blood routine test and electrocardiography were performed. Results:There were 6 cases of death,3 improved and one cured.The 6 death cases were dead in 48 h of admission to the hospital,with different degrees of cardiac shock,heart failure and arrhythmia,etc. Conclusion:The clinical features of fulminant myocarditis manifested first with digestive symptoms are not specific,which are likely to be missed in diagnosis or misdiagnosed as pediatric digestive diseases,and the best time for treatment is missed.Early diagnosis,timely correction of shock,improving cardiac function and performing positive treatment immediately can significantly reduce the mortality and improve the prognosis. Related Articles | Metrics

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Effect observation of compound glycyrrhizin injection in the treatment of children with pneumonia and liver dysfunction YANG Jinling 2016, 8 (2):  175-177.  doi: 10.3969/j.issn.1674-3865.2016.02.016 Abstract ( 785 )   PDF (351KB) ( 102 )   Save Objective:To investigate the effect of compound glycyrrhizin injection in the treatment of children with pneumonia and liver dysfunction. Methods:From January 2014 to May 2015 in Women and Children Hospital in Jiyuan city,60 children admitted to the hospital for pneumonia and liver dysfunction were randomly divided into two groups:the observation group and the control group.Two groups were both given anti-infection and inhalation therapy to treat pneumonia.The observation group was given compound glycyrrhizin injection to cure liver dysfunction,while the control group was given glucurolactone injection. Results:The total effective rate of observation group was 967%(29/30),significantly higher than the total effective rate of control group［733%(22/30)］,the difference being statistically significant(P<005).The total course of the observation group was(568±121)d,significantly shorter than the control group(922±098)d,the difference being statistically significant(P<005).The result of blood,urine and kidney function of two groups during treatment was in the normal range,with no significant adverse reactions. Conclusion:The compound glycyrrhizin injection combined with antibacterial drugs and inhalation treatment for children with pneumonia and liver dysfunction has good effect,which can not only accelerate the improvement of pneumonia,but also promote the recovery of liver function. Related Articles | Metrics

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Clinical significance of the serum lactate clearance rate and calcitonin in pediatric septic shock CHANG Jiuli 2016, 8 (2):  177-179.  doi: 10.3969/j.issn.1674-3865.2016.02.017 Abstract ( 313 )   PDF (371KB) ( 130 )   Save Objective:To explore clinical significance of the serum lactate clearance rate and calcitonin in pediatric septic shock. Methods:Totally 44 cases of septic shock patients were selected from January 2014 to May 2015 as the research object in pediatric intensive care units of our hospital.According to the disease situation they were divided into non-critical group and critical group;according to the different outcomes of patients,they were divided into survival group(34 cases)and death group(10 cases).The serum lactate clearance rate and calcitonin of two groups were compared,and their correlation was analyzed. Results:Serum lactate clearance rate of non-critical group was obviously higher than that of critical group,the difference being statistically significant(P<005);calcitonin level of non-critical group was significantly lower than that of critical group,the difference being statistically significant(P<005);lactate clearance rate of death group was obviously lower than that of the survival group，the difference being statistically significant(P<005);the level of calcitonin of death group was obviously higher than that of the survival group,the difference being statistically significant(P<005);serum lactate clearance rate and calcitonin showed a negative correlation(P<005). Conclusion:It has important clinical significance to monitor the levels of serum lactate clearance rate and calcitonin,which can be used as the important indicator of the prognosis in pediatric septic shock. Related Articles | Metrics

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Clinical effect of sequential therapy with erythromycin and azithromycin in the treatment of children with mycoplasmal pneumonia JIANG Xing，HE Liufang 2016, 8 (2):  180-182.  doi: 10.3969/j.issn.1674-3865.2016.02.018 Abstract ( 392 )   PDF (348KB) ( 131 )   Save Objective:To discuss the clinical effect of sequential therapy with erythromycin and azithromycin in the treatment of children with mycoplasmal pneumonia. Methods:From Apr.2013 to Mar.2015,a total of 48 mycoplasmal pneumonia children who accepted treatments in our hospital were taken as the clinical research objects,and these patients were randomly divided into control group(24 cases)and observation group(24 cases).Patients in the control group accepted erythromycin sequential therapy;the other patients in the observation group accepted azithromycin sequential therapy.After treatment,we compared and analyzed their clinical efficacy and safety. Results:The total effective rate of the observation group was 9167%,which was significantly higher than that of the control group(6667%),and the difference between these two groups was statistically significant(P<005);the adverse reaction rate of the observation group was 833%,which was significantly lower than that of the control group(3333%),and the difference between these two groups was statistically significant(P<005). Conclusion:Azithromycin sequential therapy,which has the advantage of high safety,is a useful approach to the children with mycoplasmal pneumonia. Related Articles | Metrics

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Sonographic features of children with secondary intussusception ZHANG Jie，LIU Lingping，YANG Fang，ZHANG Haorong，CHEN Wenjuan 2016, 8 (2):  182-184.  doi: 10.3969/j.issn.1674-3865.2016.02.019 Abstract ( 367 )   PDF (406KB) ( 110 )   Save Objective:To summarize the sonographic findings of children with secondary intussusception and provide a basis for clinical treatment. Methods:The sonographic features generated by the causes in 43 cases of secondary intussusceptions in children in Hunan Children′s Hospital from January 2011 to January 2014 were retrospectively analysed and summarized,which were diagnosed by preoperative ultrasound and confirmed by surgery and pathology. Results:Intestinal lymphoma was found in 6 cases,and there were 10 cases of colon polyps and 8 cases of enterogenous cyst;the Meckler′s diverticulum was found in 7 cases,and there were 3 cases of Crohn′s disease,2 cases of appendicitis and 3 cases of allergic purpura;small hemorrhage necrotizing enteritis was found in 2 cases,blood vessel lipoma in 1 case,congenital intestinal stenosis in 1 case. Conclusion:For children with secondary intussusception,ultrasound can be used to confirm part of the primary disease,which could be the best option for detecting the cause of intussusception.In infants with secondary intussusception,often the primary disease is enterogenous cyst;in preschool children and school-age children,intestinal polyps and Merkel diverticulum are common;school-age children and children with recurrent intussusception need to be checked for the intestinal lymphoma and Crohn′s disease while congenital intestinal stenosis should be ruled out in intestinal stenosis. Related Articles | Metrics

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Clinical analysis of infantile persistent bacterial bronchitis in 126 cases LI Junling 2016, 8 (2):  185-187.  doi: 10.3969/j.issn.1674-3865.2016.02.020 Abstract ( 501 )   PDF (371KB) ( 134 )   Save Objective:To investigate the clinical features of infantile persistent bacterial bronchitis. Methods:Totally 126 cases were selected and treated with antibiotics in the Department of Pediatrics in People′s Hospital of Ruyang County from February 2010 to March 2015,and the clinical characteristics and treatment effect were analyzed. Results:The main clinical manifestations were persistent cough,and roles could be heard;among the 126 cases,91 cases (722%) were accompanied by wheezing;it was not regular during day and night;the mean time of cough was (47±03) weeks.Edema and congestion of tracheal mucosa were observed under the microscope,and 48 cases(381%) were with airway softening.Laboratory tests showed that the proportion of CD3-CD16+ increased.The positive rate of bacterial culture in bronchoalveolar lavage fluid was 365% (46/126).The main pathogens were Haemophilus influenzae and Streptococcus pneumonia,and neutrophil elevation was 706%(89/126).The patients had good prognosis after treatment with the third generation cephalosporin or amoxicillin clavulanate,the average treatment time (154±36)d. Conclusion:The main clinical features of infantile persistent bacterial bronchitis are persistent cough with moist rales,and some children have wheezing symptoms,which can be accompanied by airway softening.The main pathogens are Haemophilus influenzae and Streptococcus pneumoniae.Positive antibiotic treatment can produce better therapeutic effect. Related Articles | Metrics

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Clinical efficacy of large dose of gamma globulin in the treatment of acute severe viral myocarditis YIN Jun，LIN Shiguang 2016, 8 (2):  187-189.  doi: 10.3969/j.issn.1674-3865.2016.02.021 Abstract ( 496 )   PDF (355KB) ( 112 )   Save Objective:To observe the clinical effect of large dose of gamma globulin on children with acute viral myocarditis. Methods:A total of 112 patients with acute severe viral myocarditis in our hospital from 2013 January to June 2015 were divided into gamma globulin group and routine group by the random number table method,56 cases in each group.The routine group was given conventional treatment,and the gamma globulin group was given large doses of IVIG in addition to the treatment for the conventional group.The course lasted for 14 days.The levels of creatine kinase isoenzyme MB(CK-MB),lactate dehydrogenase(LDH)and creatine kinase(CK)was determined before and after treatment and compared between the two groups,and ECG improvement and clinical effect were also compared. Results:CK-MB,LDH and CK levels after treatment in the two groups were significantly improved compared with those before treatment,the difference being statistically significant(P<005).Compared with the conventional treatment group,CK-MB,LDH and CK levels of the gamma globulin group improved more significantly,the difference being statistically significant(P<005).The electrocardiogram improvement rate of the gamma globulin group was 8750%,which was significantly higher than that of conventional group(7142%),the difference being statistically significant(P<005).The effective rate of the gamma globulin group was 9464%,which was significantly higher than the control group(8214%),the difference being statistically significant(P<005). Conclusion:On the basis of routine therapy,large dose of gamma globulin protein in the treatment of children with acute severe viral myocarditis can effectively improve myocardial enzyme spectrum and ECG,with significant effect.It is worthy of clinical popularization and application. Related Articles | Metrics

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Clinical effect of Insure technique in the treatment of neonatal respiratory distress syndrome ZHANG Xiaoting，PANG Yingchao，CHEN Yuping 2016, 8 (2):  190-192.  doi: 10.3969/j.issn.1674-3865.2016.02.022 Abstract ( 716 )   PDF (345KB) ( 85 )   Save Objective:To observe the clinical effect of Insure technique in the treatment of neonatal respiratory distress syndrome(NRDS). Methods:From January 2010 to December 2011,36 children with NRDS who were treated in Neonatal Department of Fuyong People′s Hospital of Baoan District were included as control group,and 42 cases of NRDS who were treated from January 2012 to December 2013 were included as the observation group.The control group was given continuous invasive positive pressure ventilation in the treatment after administration of pulmonary surfactant;the observation group was treated with Insure technology for salvage therapy.Observe the blood gas changes of two groups before and after treatment,the incidence of related complications,time of use of breathing machine and chest X-ray improvement. Results:At 5 h and 10 h after treatment,PaO2 increased significantly than before in both groups,while PaCO2 was significantly reduced(P<005).Before treatment and 5 h and 10 h after treatment,PaO2 and PaCO2 had no statistically significant difference between the two groups(P>005).In observation group incidence rate of air leak and ventilator-associated pneumonia was 238%(1/42)and 952%(4/42),which was lower than control group［1667%(6/36),2778%(10/36)］respectively,the difference being not statistically significant(P>005).In the observation group,the length of ventilation on the machine was(329±108)d,significantly shorter than the control group(545±089)d,the difference being statistically significant(P<005).The improvement rate of 12 h lung field transparency in the observation group was 905%(38/42),while in the control group it was 917%(33/36),the difference being not statistically significant(P>005). Conclusion:Insure technique is used to treat NRDS with satisfactory curative effect,which can reduce the duration of ventilator use and the occurrence of related complications. Related Articles | Metrics

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Observation on the curative effect of Xihuang pill treatment for mesenteric lymphadenitis in children QIN Yusheng，YAO Xiuyun，WANG Xiaohong 2016, 8 (2):  193-195.  doi: 10.3969/j.issn.1674-3865.2016.02.023 Abstract ( 497 )   PDF (397KB) ( 121 )   Save Objective:To observe the clinical efficacy and safety of Xihuang pill treatment for mesenteric lymphadenitis in children. Methods:Totally 60 cases of mesenteric lymphadenitis in children were randomly divided into observation group and control group.The observation group was given oral Xihuang pill，and control group was given ribavirin granule orally.The course of treatment was 7 d. Results:The total effect rate of the observation group(933%)was significantly higher than that of the control group(733%)，and in the time of abdominal pain relief and the time for mesenteric lymph nodes to improve,the observation group was also better than the control group(P<005).The two groups were safe and had no toxic side effects during the treatment. Conclusion:Xihuang pill treatment for mesenteric lymphadenitis in children can shorten the course of disease，and is safe and effective. Related Articles | Metrics

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Observation on clinical effect of montelukast sodium in the treatment of children with cough variant asthma MA Yan,CHANG Yanyan,SUN Changhua,CHEN Yaolin 2016, 8 (2):  195-197.  doi: 10.3969/j.issn.1674-3865.2016.02.024 Abstract ( 305 )   PDF (387KB) ( 141 )   Save Objective:To observe the clinical effects of montelukast sodium in the treatment of children with cough variant asthma,and to provide an effective basis for clinical medication. Methods:Totally 80 children with cough variant asthma who accepted treatments in our hospital from April 2013 to April 2015 were taken as the research objects,and these patients were randomly divided into the control group and the observation group by the random number table method,with 40 patients in each group.In the control group,they were treated with routine treatment while in the observation group,they were treated with the montelukast sodium on the basis of the treatment for the control group.All patients received a continuous treatment for 3 months.Then,the clinical treatment effect and cough relief time and cough disappearance time of two groups of patients were observed and compared. Results:After the treatment,the total effective rate in the observation group was 950%,which was significantly higher than that in the control group(775%)(P<005),and the difference had statistical significance.In addition,the cough relief time in the observation group was(514±129)d,which was significantly shorter than that in the control group(981±156)d;the cough disappearance time was(652±158)d,which was significantly shorter than that in the control group(1079±186)d(P<005),and the difference had statistical significance. Conclusion:The clinical effects of montelukast sodium in the treatment of children with cough variant asthma are good,thus should be promoted and applied in the clinics. Related Articles | Metrics

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Effect comparison of physical cooling with drug cooling in treating children with high fever LI Lifeng 2016, 8 (2):  198-200.  doi: 10.3969/j.issn.1674-3865.2016.02.025 Abstract ( 328 )   PDF (351KB) ( 104 )   Save Objective:To investigate the clinical effect of physical cooling and drug cooling in treating children with high fever. Methods:A total of 195 cases of high fever in our hospital from March 2013 to May 2014 were selected and divided into two groups,103 cases in observation group and 92 cases in control group.Observation group was given physical cooling and control group was given drug cooling.Observe the treatment effect after 2,4 and 6 hours,respectively. Results:Total effective rate and obvious effective rate of the two groups 2 h after treatment had no statistical significance(P>005).After 4 and 6 h,total effective rate and obvious effective rate of observation group were obviously higher than control group,the difference being statistically significant(P<005). Conclusion:Physical cooling is quick and effective in treating children with high fever. Related Articles | Metrics

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Observation of curative effect of the treatment of asthma in children with ventolin and Pulmicort aerosol for children with asthma WANG Yiwen，ZHANG Kongliang，LIU Xiangyu，XU Haiming 2016, 8 (2):  200-202.  doi: 10.3969/j.issn.1674-3865.2016.02.026 Abstract ( 304 )   PDF (391KB) ( 138 )   Save Objective:To observe the curative effect of the treatment with ventolin and Pulmicort aerosol for children with asthma. Methods:Totally 90 cases of children with asthma treated in our hospital from January 2014 to January 2015 were selected and randomly divided into the observation group and the control group，45 cases in each group.The children in control group were only treated with Pulmicort，while children in the observation group were treated with ventolin based on the therapy of the control group，three days as a course.The therapeutic effects of the two groups and the changes in the level of pulmonary function were observed before and after treatment，and the adverse reactions of two groups during the treatment were also observed. Results:The total effective rate of the observation group was 97.8%(44/45)，which was significantly higher than that ［82.2%(37/45)］ in the control group.The differences were statistically significant(P＜0.05).After treatment，the forced vital capacity(FVC)，forced expiratory volume in one second(FEV1) and peak expiratory flow(PEF) levels in patients in the observation group were significantly higher than those in the control group，and the differences had statistical significance(P＜0.05).There was no adverse drug reaction in the two groups during medication period. Conclusion:The treatment for children with asthma with ventolin and Pulmicort aerosol is significant.This treatment method can effectively improve the patient's clinical symptoms and signs and strengthen the level of pulmonary function，which is safe and reliable. Related Articles | Metrics

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Clinical observation on the therapeutic effect of electronic biofeedback combined with facial massage and acupuncture on peripheral facial paralysis in children ZHANG Rong 2016, 8 (2):  203-205.  doi: 10.3969/j.issn.1674-3865.2016.02.027 Abstract ( 297 )   PDF (421KB) ( 89 )   Save Objective:To observe the effect of electronic biofeedback instrument combined with facial massage and acupuncture in the treatment of children with peripheral facial nerve paralysis. Methods:From June 2013 to January 2014 in Hu'nan Provincial Children′s Hospital 70 cases of peripheral facial paralysis patients were randomly divided into observation group and control group,with 35 cases in each group.Control group was given routine medicine and physical therapy，while the observation group was added electronic biofeedback instrument combined with a special facial massage and acupuncture.The treatment lasted for 1 month.The nursing method included psychological nursing，eye nursing，dental nursing，diet nursing and life nursing and the patients were guided to take rehabilitation exercise.After the treatment，the treatment effects of two groups were compared. Results:Total efficiency of two groups had no significant difference(P>005).In the observation group markedly effective rate was 971%(34/35)，higher than that of the control group［771%(27/35)］，the difference being statistically significant(P<005). Conclusion:Electronic biological feedback therapy and facial massage and acupuncture therapy are effective on children with facial paralysis when used in combination，and it is worth clinical application. Related Articles | Metrics

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Study on medication characteristic and management of Zhang Wenhuan in treating children with spleen and stomach disease based on 150 prescriptions SONG Hujie，LI Fangfang，WANG Hui 2016, 8 (2):  206-209.  doi: 10.3969/j.issn.1674-3865.2016.02.028 Abstract ( 382 )   PDF (450KB) ( 82 )   Save Objective:To analyze medication characteristic of ZHANG Wenhuan in treating pediatric spleen and stomach disease based on the prescription management system software of TCM inheritance school.Mr.Zhang is one of the representative inheritors of second generation of Xiqi Wang′s Jishitang pediatric academic TCM school. Methods:Collect 32 volumes of prescription stubs(more than 1 500 prescriptions) of Mr.Zhang from 1963 to 1966.These prescription stubs were numbered,taken photos,filed and annotated in proper sequence,and 405 pediatric prescriptions were entered in the system.Select 150 prescriptions of pediatric spleen and stomach disease and perform research based on statistical data processing,and analyze drug frequency,association rules among drugs and prescription patterns. Results:Through analysis of 150 pediatric spleen and stomach disease prescriptions,it was found that liquorice was used the most frequently.In accordance with the order of the drug in frequency from high to low,the top six drugs were liquorice,dried tangerine or orange peel,atractylodes,poria cocos,rhizoma atractylodis and charred triplet.At the same time the medicine to tonify deficiency appeared most frequently,followed by damp dispel diuretic drugs,and qi-regulating drugs,heat-clearing drugs and aromatic damp-resolving drugs. Conclusion:Based on the prescription management system software platform of TCM inheritance school,study on the data mining and medication regulation of Mr.Zhang in treating children with spleen and stomach disease not only provides effective guidance for clinical treatment of children with spleen and stomach disease,but also provides the basis for better inheriting the academic thoughts. Related Articles | Metrics

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Experience in treating child diseases based on indigestion theory WANG Peiyuan，LAO Huimin，MA Ting，XING Xiaoli 2016, 8 (2):  209-211.  doi: 10.3969/j.issn.1674-3865.2016.02.029 Abstract ( 397 )   PDF (481KB) ( 154 )   Save The internal organs of children are delicate and lack of qi,so their spleen,lung and kidney are often weak.If feeded improperly and nursed without care,they are likely to have indigestion,resulting in the damage to spleen and stomach.The internal organs are interrelated,which means that one organ damaged may harm the other organs;diarrhea occurs as a result of the insufficiency of spleen,and cough is present because of the damage to lung, and due to the heat of heart,there is insomnia and restlessness.Recently,with the improvement of life and the change of diet structure,indigestion has become a clinically common pathological product and disease factor.Based on 4 cases commonly seen in clinics,this paper discussed the mechanism of indigestion causing diseases in children,and the theories and treatment methods were also studied according to differentiation treatment theory for child diseases based on traditional Chinese medicine. Related Articles | Metrics

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Essential items of Chinese medicine body constitution scale for children in Lingnan area:a Delphi survey LIU Zhuoxun,YANG Jinghua,DENG Lijun,XU Youjia 2016, 8 (2):  212-216.  doi: 10.3969/j.issn.1674-3865.2016.02.030 Abstract ( 501 )   PDF (659KB) ( 157 )   Save Objective:To lay necessary foundation for development of Body Constitution Scale for children in Lingnan area,Delphi method was applied to evaluate and select essential items for body constitution classification. Methods:Based on previous studies on literature and clinical experience,seven types of body constitutions,including normal constitution,qi-deficiency constitution,yang-deficiency constitution,yin-deficiency constitution,dampness-heat constitution,phlegm-damp constitution and qi-stagnation constitution,were established and all related symptoms and signs were listed as items for screening.Twenty-eight specialists were inquired in the two rounds of consultation using self-made Delphi questionnaire. Results:Response rates in the two rounds of consultation were 100% and 929%,respectively.Of the initial 49 items,17 were removed and one modified after Round 1 and in the remained 31 items,6 items were combined into 3.The 29 items were surveyed in Round 2 and all reached the criteria and the average score of each item was higher than 15,ratio of full score higher than 50%,and coefficient of variance less than 03. Conclusion:By Delphi method,a Body Constitution Scale for children in Lingnan area has been initially developed with eligible reliability and representativeness， which lays a solid foundation for the development of the following scale. Related Articles | Metrics

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Analysis of 28 479 cases of hand-foot-and-mouth disease in Dalian from 2010 to 2013 GAO Yanhui,LIU Yan,SUN Di 2016, 8 (2):  217-219.  doi: 10.3969/j.issn.1674-3865.2016.02.031 Abstract ( 388 )   PDF (409KB) ( 87 )   Save Objective:To understand epidemiological characteristics and pathogenic features of hand-foot-and-mouth disease in Dalian from year of 2010 to 2013. Methods:Analyze clinical data of 28 479 hand-foot-and-mouth disease cases treated in Dalian Children′s Hospital from January 2010 to December 2013.Clinical severe children′s feces or throat formula was sent for detection,and the two pathogens of EV71 and CA16 were detected.Observe the status in each month of hand-foot-and-mouth disease,time distribution of in-patient cases and severe hand-foot-and-mouth disease cases，and result of severe children′s enterovirus. Results:The largest quantity of cases was 7 587 in year of 2012,and this number increased each year in May,and the infection number occupied 7397%～8373% of the whole year， especially from June to August every year.The infection peak month was in July from 2010 to 2012 and August in 2013,and it declined obviously in September. Conclusion:Most cases of hand-foot-and-mouth disease in 2010 are associated with EV71 infection and the largest quantity of hand-foot-and-mouth disease case is in year of 2012 which is probably associated with CA16 infection.Most atypical hand-foot-and-mouth disease cases are in 2013 and disease peak moves from July of 2010～2012 to August of 2013,which is probably associated with CA6 infection. Related Articles | Metrics

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Investigation of family environment of children with dust mites allergy in Shenyang WANG Wei，LI Yao，WEI Qingyu,MU Yaping 2016, 8 (2):  220-222.  doi: 10.3969/j.issn.1674-3865.2016.02.032 Abstract ( 250 )   PDF (383KB) ( 113 )   Save Objective:Investigation and analysis of relationship between dust mite allergy in children and family environment in Shenyang City is made to provide basis for prevention and treatment. Methods:A total of 400 HDM-allergic children were enrolled from the clinics in Shenyang Children′s Hospital from June 2011 to September 2014 (290 asthma and 85 rhinitis，25 urticaria) and questionnaire survey was performed,and logistic regression analysis was used to evaluate the risk factors of dust mite allergy. Results:Carpet (OR=411) cloth sofa (OR=389) and plush toys (OR=365) had significant relation with dust mite allergy. Conclusion:Carpet,cloth sofa and plush toys are the main risk factors of children with dust mites allergy,so it is recommended that dust mite allergy sufferers had better avoid carpet,cloth sofa and push toys in their family. Related Articles | Metrics

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Analysis of viral infection of respiratory tract in children with pneumonia in Ji′nan area in winter ZHENG Binru，ZHANG Baoqing 2016, 8 (2):  222-224.  doi: 10.3969/j.issn.1674-3865.2016.02.033 Abstract ( 307 )   PDF (370KB) ( 134 )   Save Objective:To investigate the respiratory virus infection in hospitalized children with pneumonia in Ji′nan area in order to provide evidence for clinical diagnosis and treatment. Methods:From December 2014 to February 2015 in the Affiliated Hospital of Shandong University of Traditional Chinese Medicine,the clinical data of 208 hospitalized children with bronchial pneumonia were collected.The common respiratory tract virus was detected by direct immunofluorescence assay in the nasal secretions of the patients,including respiratory syncytial virus,adenovirus,influenza virus and parainfluenza virus. Results:The male infection rate was 6847%(76/111)in 208 cases,and the female infection rate was 6701%(65/97).The difference was not statistically significant(P>005).In 208 cases of bronchial pneumonia children,respiratory virus infection occurred in 141 patients(6779%),in which there was single virus infection in 56 cases(397%),2 or more than 2 kinds of virus infection in 85 cases(6029%);the infection rate of respiratory syncytial virus and influenza A was the highest.The infection rate was 7742%(48/62)in children under 3 years old,6142%(78/127)in children aged 3 to 6 years,and 7894%(15/19)in children over 6. Conclusion:Respiratory tract virus and influenza virus A are the main pathogen of infection in children with pneumonia in Ji′nan area. Related Articles | Metrics

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Clinical analysis of short stature in 155 children in Nanyang NIU Wenzhong，DING Xianchun 2016, 8 (2):  225-227.  doi: 10.3969/j.issn.1674-3865.2016.02.034 Abstract ( 327 )   PDF (463KB) ( 106 )   Save Objective:To analyze the etiology of short stature in children in Nanyang. Methods:Totally 155 children with short stature were selected from October 2009 to February 2015 in Pediatric Department of Nanyang Central Hospital.Detailed records of general information and history were collected;the height and the growth and development situation of their parents and other members of the family were investigated;physical check-up and auxiliary examination were performed. Results:Among 155 cases of short stature，72 cases were diagnosed with growth hormone deficiency(4645%)，50 cases with idiopathic short stature(3226%)，10 cases with constitutional delay of growth and puberty(645%)，5 cases with small for gestational age(323%)，6 cases with hypothyroidism(387%)，4 cases with idiopathic central precocious puberty(258%)，3 cases with Turner's syndrome(194%)，3 cases with achondroplasia(194%)，and 2 cases with mucopolysaccharidosis(129%). Conclusion:Growth hormone deficiency and idiopathic short stature are common etiological factors of short stature in Nanyang. Related Articles | Metrics

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Analysis of site and cause of gastrointestinal bleeding in children of different ages LUO Weiyao，LIU Zhigang，HE Yun，HE Xiaocheng，PENG Sheng 2016, 8 (2):  228-230.  doi: 10.3969/j.issn.1674-3865.2016.02.035 Abstract ( 392 )   PDF (369KB) ( 139 )   Save Objective:To investigate the characteristics of the bleeding site and cause of peptic ulcer in children of different ages. Methods:A total of 142 children admitted to Foshan Women and Children Hospital for gastrointestinal bleeding from June 2014 to June 2015 were included in the study.They were divided into 4 groups according to age:group Ⅰ(34 cases)aged 3 months to 1 year,group Ⅱ(23 cases)aged one year to 4 years,group Ⅲ(38 cases)aged 4 to 7 and group Ⅳ(47 cases)aged 7 to 15.The site and cause of bleeding were compared. Results:In the 142 cases,the main clinical manifestation was tarry stools,and blood stool in bright red was common in the lower gastrointestinal bleeding.There were 73 cases of lower gastrointestinal bleeding.The main cause was allergic prupura,followed by acute and chronic diarrhea.Comparing the number of cases of allergic purpura and acute and chronic diarrhea in different age groups,there was statistical difference(P<005). Conclusion:For children with gastrointestinal bleeding,the detailed history should be recorded.Esophagitics,gastric ulcer and duodenal ulcer are common in upper gastrointestinal bleeding,while in the lower bleeding,allergic purpura and acute and chronic diarrhea are more commonly seen.Clinically multiple methods of diagnosis and treatment should be used to observe the disease in order to screen for the suitable treatment. Related Articles | Metrics

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Application of professor Diao Benshu′s thought about the spleen and stomach disease to pediatric exogenous fever DU Yuan，WANG Wei，DIAO Benshu 2016, 8 (2):  231-233.  doi: 10.3969/j.issn.1674-3865.2016.02.036 Abstract ( 293 )   PDF (487KB) ( 108 )   Save The spleen and stomach is the source of Qi and blood,called “foundation of acquired constitution” in traditional Chinese medicine,which has a very important  position in the theory of TCM,especially in pediatric physiology and pathology known as “infantile spleen is often insufficient” argument.Prof.Diao Benshu always puts emphasis on “spleen and stomach” thought in treating epidemic febrile diseases,and he puts forward correspondingly the three-word principle of “Gu,Jian,Yang”.Based on specific cases, this paper illustrated the unique syndrome differentiation rule in the treatment of infantile fever. Related Articles | Metrics

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Application value of evidence-based nursing in reducing complications of NCPAP in the newborn CHEN Suxiang,JIANG Shan 2016, 8 (2):  234-236.  doi: 10.3969/j.issn.1674-3865.2016.02.037 Abstract ( 540 )   PDF (381KB) ( 87 )   Save Objective:To explore the clinical application value of evidence-based nursing in reducing complications of nasal continuous positive airway pressure(NCPAP)in the newborn. Methods:Totally 77 cases of neonates who underwent the Nasal CPAP treatment in Luohu District Maternal and Child Health Care Hospital were taken as the research objects,and the patients were randomly divided into the routine nursing group of 39 cases and the evidence-based nursing group of 38 cases according to the admission sequence.The occurrence of complications related to CPAP in the newborn of the two groups after nursing was compared and the differences of nursing satisfaction were recorded. Results:①After nursing,the occurrence rate of CPAP-related complications in routine group was 308%,which was significantly higher than 79% of evidence-based group and the difference was statistically significant(P<005);②the nursing satisfaction of routine group was 59%,which was significantly lower than 921% of evidence-based group and the difference was statistically significant(P<005). Conclusion:For the newborn with NCPAP treatment,evidence-based nursing can effectively reduce the risk of related complications and improve the clinical nursing satisfaction,which is worthy of promotion. Related Articles | Metrics

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Study on the application of optimized infusion process in pediatric outpatient emergency department LIU Limin，TANG Yinglong，ZHAO Xiaoping，LIU Huayan 2016, 8 (2):  237-239.  doi: 10.3969/j.issn.1674-3865.2016.02.038 Abstract ( 375 )   PDF (330KB) ( 125 )   Save Objective:To observe the effect of optimized infusion process in pediatric outpatient emergency department. Methods:A total of 700 children received infusion in Hunan Children's Hospital from June 2011 to June 2014，and they were divided into two groups: the observation group(350 cases) and the control group(350 cases).The observation group was given optimized infusion process，and the control group received conventional one.Compare and analyze infusion result of the two groups，including infusion waiting time，families' satisfaction with the infusion treatment and nursing accidents during infusion. Results:The average waiting time for infusion was (10.98±3.49)min in the observation group，significantly shorter than that of the control group (31.04±4.12)min，the difference being statistically significant(P＜0.05).Families' satisfaction degree was 97.7%(342/350) in the observation group，significantly higher than that of the control group［86.9% (304/350)］，and the difference was statistically significant(P＜0.05).The rate of nursing accidents was 5.7%(20/350) in the observation group，which was greatly lower than that of the control group［17.7%(62/350)］，with statistical difference(P＜0.05). Conclusion:Optimized infusion process has better effect than conventional one in the pediatric outpatient emergency department and should be clinical used. Related Articles | Metrics

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Influence of phototherapy time on the buttock skin temperature and the effect of early warning intervention YANG Qian，LIU Yongqin 2016, 8 (2):  239-241.  doi: 10.3969/j.issn.1674-3865.2016.02.039 Abstract ( 401 )   PDF (363KB) ( 88 )   Save Objective:To study the influence of phototherapy time on the buttock skin temperature and to discuss the effect of early warning intervention in preventing the buttock skin damage. Methods:Select 100 cases of jaundice in hospitalized neonates in Neonatal Department of the First People's Hospital of Wujiang from January to April 2014 and divide them randomly into conventional group and experimental group with 50 cases in each.The two groups were given routine nursing，and the same treatment.The buttock skin of the conventional group was protected by 3M painless protective membrane，while the experimental group was given 3M painless protective membrane protection before phototherapy and was post the artificial skin protection along the ischial tuberosity to anal Monday circle，with 3M 9534HP film coating protection outside the artificial skin. Measure the buttock skin temperature of the two groups before phototherapy and 2 hours，4 hours，6 hours and 8 hours after phototherapy.Record the incidence of buttock skin damage in the two groups. Results:Body temperature before phototherapy，2 hours and 4 hours after phototherapy of the two groups had no significant difference(P＞0.05).However body temperature of 6 hours and 8 hours after phototherapy of the conventional group were higher than that of the experimental group，which had statistical significance(P＜0.05).Body temperature in each time period of 2 hours，4 hours，6 hours and 8 hours after phototherapy of the two groups were higher than that before phototherapy(P＜0.01).The incidence rate of the buttock skin damage after the early warning intervention of the experimental group was 2%（1/50），which was significantly better than the conventional group［16%（8/50）］，the difference having statistical significance（P＜0.05）. Conclusion:Phototherapy causes the buttock skin temperature to rise and the incidence rate of buttock skin damage is reduced after the early warning intervention. Related Articles | Metrics

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Management of health education for children with asthma in out-patient department YANG Dongmei 2016, 8 (2):  242-244.  doi: 10.3969/j.issn.1674-3865.2016.02.040 Abstract ( 530 )   PDF (455KB) ( 111 )   Save Objective:To improve the prevention and treatment of children with asthma through systematic health education for children with bronchial asthma and their parents. Methods::A total of 157 cases of bronchial asthma were randomly divided into two groups:the observation group(87 cases)and the control group(77 cases).The control group was given health education by talking in OPD,while for the observation group,in addition to the management for the control group,asthma information was recorded in files and systematic health education was performed for the children and their parents.After 3 months,the lung function and control of asthma were evaluated. Results:After 3 months of treatment,there was statistical difference in the asthma attack,accuracy of inhalation operation,pulmonary ventilation and treatment compliance by comparing the two groups(P<001). Conclusion:Systematic health education increases the recognition level of asthma in children and their parents,through which the children have better compliance and asthma is effectively controlled.It helps to prevent and treat asthma in children and reduces their pain.   Related Articles | Metrics