Table of Content

25 February 2016, Volume 8 Issue 1 Previous Issue    Next Issue

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Clinical study on asthmarelieving prescription for children with thermal asthma  LI Meihua，XUE Zheng，RUAN Yanyan，JIANG Yonghong，CHEN Weibin 2016, 8 (1):  1-3.  doi: 10.3969/j.issn.1674-3865.2016.01.001 Abstract ( 356 )   PDF (1KB) ( 109 )   Save Objective：To observe the clinical effect of asthma-relieving prescription for children with thermal asthma by multi-center research method. Methods：A total of 180 children were included in the study，who were admitted to the Pediatric Department of the 3 affiliated hospital of Shanghai TCM University from August 2014 to June 2015 for thermal asthma at acute stage.They were divided into two groups:the control group and the observation group，with 90 cases in each group.The observation group was treated with asthma-relieving prescription，and the control group was given Maxing Shigan decoction for treatment.The treatment lasted for 7 days，and compare the score change of main symptoms and signs as well as the clinical effect before and after treatment between the two groups. Results：The score of main symptoms and signs in two groups(wheezing，cough，chest tightness，wheezing rale) were decreased after treatment，the difference being statistically significant(P＜0.05)，and these scores in the observation group were smaller than those of the control group after treatment，the difference being of statistical significance(P＜0.05).The total effective rate was 96.7%(87/90) in the observation group，significantly higher than that of the control group［83.3%(75/90)］，and the difference was statistically significant(P＜0.05). Conclusion：The asthma-relieving prescription has good effect in the treatment of children with thermal asthma at acute stage，and it's better than Maxing Shigan decoction. Related Articles | Metrics

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Related factors influencing clinical efficacy of combined massage and plastering therapy of TCM on children with chronic and persistent diarrhea CHEN Yanxia，GUO Kai，MAO Na，WANG Hongjuan，ZHANG Li，LONG Xiaoya，HUANG Changting，HOU Tiantian，KANG Bo，MENG Yingchao，XIAO Heyin 2016, 8 (1):  4-7.  doi: 10.3969/j.issn.1674-3865.2016.01.002 Abstract ( 464 )   PDF (506KB) ( 103 )   Save Objective：To evaluate the clinical efficacy of combined massage and plastering therapy of TCM on children with chronic and persistent diarrhea.To investigate the related factors influencing clinical efficacy of combined massage and plastering therapy of TCM on children with chronic and persistent diarrhea. Methods：Individual diet prescription，massage and plastering therapy of TCM were used for 82 children with chronic and persistent diarrhea.The scores of TCM syndrome were observed before and after 7 days of treatment.The effective group included cured and improved patients，and the contrastive analysis was made between the effective group and ineffective group. Results：At the end of the 7 days of treatment，29 cases were cured（35.4%），46 cases were improved（56.1%），while 7 cases had no response（8.5%）.All the child patients who recovered and improved were included in the effective group，75 cases in total（91.5%）.The stool frequency of the children before sickness and the special milk powder were negatively correlated with efficacy，while the food supplement was positively correlated with efficacy. Conclusion：Combined treatment of massage and plastering therapy of TCM has satisfactory effectiveness in treating children with chronic and persistent diarrhea.The stool times of the children before getting sick，the special milk powder and the supplementary food addition are relevant factor affecting curative effect. Related Articles | Metrics

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Research on the relationship between clinical symptoms of allergic Henoch-Schonlein purpura and purpura nephritis in children HUANG Liqing，LI Lihua，ZHOU Xiyou 2016, 8 (1):  7-9.  doi: 10.3969/j.issn.1674-3865.2016.01.003 Abstract ( 389 )   PDF (351KB) ( 96 )   Save Objective：To investigate the relationship between clinical symptoms of children with allergic purpura and Henoch-Schonlein purpura nephritis in children. Methods：Totally 200 cases of children with allergic purpura treated in the Department of Women and Children Health Care Hospital of Baoan District of Shenzhen city from May 2013 to April 2015 were divided into two groups:purpura nephritis group(109 cases) and nonnephritis group(91 cases) according to whether or not having concurrent nephritis.The age and clinical symptoms of the two groups were analyzed by single factor and Logistics multifactor analysis(recurrence time of rash，bleeding of digestive tract，abdominal pain，joint pain，and edema of the blood vessels). Results：Single factor analysis showed that children with allergic purpura nephritis was significantly related to age，recurrence time of skin rash，digestive tract bleeding，abdominal pain and joint pain(P＜0.01).The logistics nonconditional multivariate analysis showed that age，which is more than or equal to 8 years old，time period of recurrent rash，which is more than or equal to 4 weeks，digestive tract bleeding，abdominal pain and joint pain were the independent risk factors for children with allergic purpura nephritis（P＜0.01）. Conclusion：The development of allergic purpura nephritis is closely related to the clinical symptoms. Age，which is more than or equal to 8 years old，time period of recurrent rash，which is more than or equal to 4 weeks，digestive tract bleeding，abdominal pain and joint pain are independent risk factors for purpura nephritis(HSPN). Related Articles | Metrics

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Study on the relationship between serum eosinophil cationic protein and IgE in children with bronchial asthma in acute stage SHANG Lili，XIANG Li'e 2016, 8 (1):  10-12.  doi: 10.3969/j.issn.1674-3865.2016.01.004 Abstract ( 301 )   PDF (396KB) ( 109 )   Save Objective：To study the correlation between serum eosinophil cationic protein(ECP) and immunoglobulin E(IgE) in children with acute attack of bronchial asthma. Methods：From January to December 2013，30 cases of mild-to-moderate bronchial asthma children in acute phase who were treated in the First Affiliated Hospital of Anhui Traditional Chinese Medical University were chosen as observation group.At the same time select 30 cases of healthy children as the healthy control group.Use the double antibody ELISA method to determine serum ECP and IgE level of two groups. Results：The ECP and IgE in the observation group were significantly higher than those in the control group(P＜0.01).ECP and IgE in the observation group had significantly positive correlation(r=0.471，P＜0.01). Conclusion：Determination of serum IgE，ECP level can reflect the severity of airway inflammation，so they can be used as indexes of airway inflammation detection in bronchial asthma. Related Articles | Metrics

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Analysis of ultrasonographic diagnosis of acute mesenteric lymphadenitis in children LIU Chuanshuang，YU Bing 2016, 8 (1):  12-14.  doi: 10.3969/j.issn.1674-3865.2016.01.005 Abstract ( 382 )   PDF (415KB) ( 87 )   Save Objective：To summarize the clinical features of ultrasonographic diagnosis of acute mesenteric lymphadenitis in children. Methods：The Japan Aloka alpha 7 high frequency probe was used to examine the child's abdomen by multi-section scanning.The observation was focused on the mesenteric root，and lymph node location and number were recorded;measure internal echo as well as the size and shape;observe the flow distribution and record the resistance index.After anti-infection symptomatic treatment，the patients were reexamined by ultrasound，and the results were analyzed through combination with high frequency ultrasonographic diagnosis. Results：All the patients were accurately diagnosed by ultrasound;54 cases were had abdominal pain as the main symptom.The onset of the disease was more common in children under 7 years old，and more likely to be in winter and spring.The upper respiratory tract infection was a common cause of infection，and after anti-inflammatory and antiviral treatment，all recovered. Conclusion：Ultrasonographic examination of children with acute mesenteric lymphadenitis is a reliable evidence in the diagnosis of the disease，and early discovery and treatment will result in better prognosis. Related Articles | Metrics

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Clinical features of severe mycoplasma pneumoniae pneumonia in 39 children and analysis of curative effect of glucocorticoids YIN Xiaobo,WU Xiuqing,SHI YIfang,MAO Zhiqin,MU Yaping 2016, 8 (1):  15-18.  doi: 10.3969/j.issn.1674-3865.2016.01.006 Abstract ( 408 )   PDF (586KB) ( 75 )   Save Objective：To analyze the clinical features of severe mycoplasma pneumoniae pneumonia(MPP) and observe the curative effect of glucocorticoids． Methods：A total of 39 children hospitalized for severe mycoplasma pneumoniae pneumonia from July 2013 to December 2013 were divided into glucocorticoid group and control group.Compare the time of fever relief and spasmatic cough and hospital stay between the two groups. Results：All the 39 cases of children had the symptom of fever and spasmatic cough,which lasted for 5 to 10 days.There were 29 cases whose white blood cell increased.Large piece of shadow or pulmonary infiltrates shadows were found in imaging examination,including 5 cases in both sides of lung and 34 cases in one side.All serum MP-IgM was equal to or more than 160．Eight cases had pleural effusion,2 cases had pulmonary atelectasis,and 6 cases had abnormal liver function.Myocardial enzyme spectrum was abnormal in 5 cases,and erythra was found in 2 cases.The time of fever and spasmatic cough of the glucocorticoid group was (6.7±1.3）d and （5.35±1.62）d, less than （8.3±1.4）d and （7.27±1.58）d of the control group(P＜0.05).The length of hospital stay of glucocorticoid group and control group was （14.8±6.2）d and（12.8±3.3）d(P＞0.05),respectively,and there was no difference between the two groups. Conclusion：Severe mycoplasma pneumoniae pneumonia of children can lead to severe intrapulmonary infection and a variety of extrapulmonary complications.Early use the glucocorticoids can result in good effect. Related Articles | Metrics

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Observation on the effect of Smecta in adjuvant treatment for herpetic stomatitis WANG Dongmei，SHI Jingjing 2016, 8 (1):  19-21.  doi: 10.3969/j.issn.1674-3865.2016.01.007 Abstract ( 491 )   PDF (376KB) ( 103 )   Save Objective：To summarize the clinical effect of Smecta adjuvant treatment for herpetic stomatitis. MethodsSelect 62 patients with herpetic stomatitis treated in our department from April 2014 to September 2014，and they were randomly divided into two groups：control group and observation group.The observation group was given Smectite powder on the oral ulcer surface，3 times a day.Ten minutes after treatment they could eat.The course of the treatment was 5 days.Observe the treatment effects of the two groups. Results：In the observation group，the time for fever and pain to disappear and healing time of oral ulcer was significantly higher than that of the control group，the difference being statistically significant(P＜0.05).The total effective rate was 100.0%，which was significantly higher than that of the control group(80.0%)(P＜0.05). Conclusion：Application of Smectite on the affected areas in treatment of herpes stomatitis can relieve pain and accelerate ulcer healing;the result is satisfactory，and it has certain clinical application value. Related Articles | Metrics

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Observation on the effect of acupuncture combined with electroacupuncture in the treatment of acute facial neuritis at acute stage CHENG Xiandan 2016, 8 (1):  21-23.  doi: 10.3969/j.issn.1674-3865.2016.01.008 Abstract ( 310 )   PDF (396KB) ( 114 )   Save Objective：To observe the curative effect of acupuncture combined with electroacupuncture on children with acute facial neuritis at acute stage. Methods：Totally 80 children with acute facial neuritis at acute stage were randomly divided into two groups:observation group(n=40) and control group(n=40).Acupuncture combined with electro acupuncture treatment was performed at acute stage（1～7 days of onset） in the observation group，and it was performed at stable stage（8～15 days of onset） in the control group.The other treatments were the same in both groups，such as hormone therapy，antivirus therapy，nervous nutrition therapy，and so on，and the longest treatment lasted for one month. Results：The time of recovery and being effective and cured was shorter in observation group,and the difference was statistically significant（P＜0.05）.The cure rate in observation group（90%） was higher than the control group(55%)，and the difference was statistically significant（P＜0.05）. ConclusionFor children with acute facial neuritis，acupuncture and electroacupuncture treatment at acute stage can shorten the course of treatment，achieving effect early，which can improve the cure rate in a limited time. Related Articles | Metrics

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Clinical observation of different therapeutic schemes in the treatment of neonatal stress ulcer hemorrhage ZHENG Xuemei 2016, 8 (1):  24-26.  doi: 10.3969/j.issn.1674-3865.2016.01.009 Abstract ( 403 )   PDF (378KB) ( 94 )   Save Objective：To compare the therapeutic effect of different schemes on the stress ulcer bleeding in newborn infants. Methods：A total of 80 cases of stress ulcer bleeding in children in our hospital from March 2012 to December 2014 were selected as the research subjects，and by the random double blind method，the cases were divided into two groups，each with 40 cases;the control group received routine treatment of fasting，primary disease symptomatic intervention，while the observation group was given the same treatment for the control group combined with hemocoagulase treatment;compared clinical curative effect，the main symptoms disappearance time and adverse reaction of the two groups. Results：The total effective rate was 95.0% in the observation group and 80.0% in the control group，the difference being statistically significant(P＜0.05).The disappearance time of gastrointestinal dysfunction was ［（4.68±0.78）d vs （7.86±0.82）d］ respectively，disappearance time of bad circulation was ［（1.88±0.53）d vs（3.92±0.35）d］ respectively，and the time to stop bleeding was respectively ［（1.28±0.70）d vs（2.82±0.84）d］，the difference being statistically significant(P＜0.01).There were no significant adverse reactions in both two groups. Conclusion：Conventional therapy combined with blood coagulation intervention can significantly shorten the bleeding time，and the effect is exact，which can be used as an important means of managing neonatal stress ulcer bleeding. Related Articles | Metrics

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Observation on the effect of onestop health care model to improve the quality of child health care LIANG Chunxiao，CAI Chunmei，ZHONG Xinghua，CHENG Ziying 2016, 8 (1):  26-28.  doi: 10.3969/j.issn.1674-3865.2016.01.010 Abstract ( 530 )   PDF (392KB) ( 144 )   Save Objective：To explore the effective method to improve the quality of health care in children. Methods：From December 2013 to December 2014，88 children were given health care in our hospital and they were randomly divided into two groups:control group and observation group，44 cases in each group.The control group was given the traditional child health care service.The observation group was given one-stop health care service.Service waiting time，coverage rate，system management rate，and parents' satisfaction with health care services of the two groups were observed and compared. Results：(1)The average waiting time of children in the control group was (55.45±8.56)min，significantly higher than that in the observation group (33.98±5.02)min，and the difference was statistically significant(P＜0.05).(2)The coverage rate and system management rate of the observation group were 72.73%(32/44) and 90.91%(40/44) respectively，which were significantly higher than those in the control group，which were 34.09%(15/44) and 45.45%(20/44)，and the difference was statistically significant(P＜0.05).(3)The parents' satisfaction rate of the observation group was 93.18%(41/44)，which was significantly higher than that of the control group 72.73%(32/44)，and the difference was statistically significant(P＜0.05). ConclusionOne-stop health care service model can effectively improve the quality of health care in children，and has significant clinical application effect and promotion value. Related Articles | Metrics

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Reasonable use of MRI in children with febrile seizuresMA Xuemei MA Xuemei 2016, 8 (1):  29-31.  doi: 10.3969/j.issn.1674-3865.2016.01.011 Abstract ( 342 )   PDF (346KB) ( 131 )   Save Objective：To investigate the results of brain MRI in children with febrile seizures in order to provide the basis for using brain MRI properly. Methods：The clinical data of 192 children with febrile seizures hospitalized from June 2013 to June 2014 examined with brain MRI were analyzed retrospectively，and the rate of abnormal brain MRI result was compared between the children with simple febrile seizures and complex febrile seizures. Results：There were 167 cases of simple febrile seizures and 25 cases of complex febrile seizures in all 192 children with febrile seizures.Abnormal brain MRI results were detected in 25 cases，the rate of abnormal MRI was 10.2% in simple febrile seizures and 32% in complex febrile seizures.There was significant difference in the rate of abnormal brain MRI between children with simple febrile seizures and complex febrile seizures. Conclusion：The brain MRI doesn't need to be used routinely in children with simple febrile seizures.If there is higher positive rate of brain MRI in children with complex febrile seizures and basic pathological changes are found，the brain MRI should be used routinely. Related Articles | Metrics

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The clinical observation on treatment for mycoplasma pneumonia with ambroxol and clenbuterol oral solution and atomized inhalation of heparinZHENG Wenli，CHENG Weili，LONG Feng，ZHANG Hong.Department of Pediatrics，the PLA 281 Hospital，Qinhuangdao 066100，China ZHENG Wenli，CHENG Weili，LONG Feng，ZHANG Hong 2016, 8 (1):  31-33.  doi: 10.3969/j.issn.1674-3865.2016.01.012 Abstract ( 335 )   PDF (370KB) ( 108 )   Save Objective：To evaluate the clinical effect of ambroxol and clenbuterol oral solution and atomized heparin in the treatment of mycoplasma pneumonia. Methods：A total of 136 patients with mycoplasma pneumonia treated in our hospital from November 2011 to November 2013 were collected.They were divided into two groups randomly，with 68 patients in each group.The patients in both groups received traditional anti-mycoplasma and comprehensive treatment for two courses，and ambroxol and clenbuterol oral solution was used for 7 days and atomized heparin for 4 to 7 days for patients in the observation group.The time for the symptoms to disappear，hospital stay，the clinical effect and side effects were observed. ResultsThe total effective rate of observation group was 97.1%(66/68) which was remarkably higher than that in the control group，which was 88.2%(60/68),and the difference was statistically significant(P＜0.05).The time for cough，moist rales and fever to disappear and hospital stay in the observation group is much less than those in the control group.All the differences were statistically significant（P＜0.05）.Neither of the groups showed clear side effects. Conclusion：The treatment for mycoplasma pneumonia with ambroxol and clenbuterol oral solution and atomized heparin is effective，safe and convenient. Related Articles | Metrics

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Music therapy on infant hypoxic ischemic encephalopathy recovery hearing affect curative effect observation KONG Lingli，LU Lu 2016, 8 (1):  34-36.  doi: 10.3969/j.issn.1674-3865.2016.01.013 Abstract ( 593 )   PDF (374KB) ( 127 )   Save Objective：To observe music therapy to treat infant hypoxic ischemic encephalopathy recovery the curative effect of hearing. Methods：In June 2013 to June 2015 Zhongxiang Maternal and Child Health Care of Family Planning Service Center of hypoxic ischemic encephalopathy is admitted in pediatric recovering from significant hearing impairment of children with 228 cases，114 cases were randomly divided into observation group and control group each.Control group using hyperbaric oxygen joint muscle injection of single silica acid has four sugar ganglioside treatment，observation group in the control group therapy based on join music therapy，and listen to music every day 4 times，each time for 20 min，1 month compared two groups of children listening to improve the situation. Results：the observation group treatment the total effective rate was 92.1%(105/114)，significantly higher than that of control group 69.3%(79/114)，the difference was statistically significant(P＜0.05).All the children in the process of music therapy without any resistance，exclusion，pain and other adverse reactions. Conclusion：compared with conventional treatment methods，combination of music therapy can significantly improve hypoxia ischemic encephalopathy recovery has children with hearing impairment of hearing recovery effect，and gentle treatment is simple，treatment contents，easily accepted by children，no side effects. Related Articles | Metrics

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Feasibility analysis of antihepatitis B immunoglobulin combined with hepatitis B vaccine in blocking the transmission of hepatitis B virus infection between father and infant MA Yanni 2016, 8 (1):  36-38.  doi: 10.3969/j.issn.1674-3865.2016.01.014 Abstract ( 325 )   PDF (382KB) ( 86 )   Save Objective：To observe the clinical effect of anti-hepatitis B immunoglobulin combined with hepatitis B vaccine in blocking the transmission of hepatitis B virus infection between father and infant. Methods：Totally 68 pairs of pregnant women and their spouses in People's Central Hospital in Zhanjiang from January 2012 to May 2015 were selected as the subjects of study and were randomly divided into the observation group and the control group，34 pairs in each group，among whom women were not infected with hepatitis B virus but their spouses were hepatitis B patients.The newborns in the control group were injected with hepatitis B vaccine while the newborns in the observation group were injected antihepatitis B immunoglobulin on the basis of the treatment for the control group.The birth weight，Apgar scores，the levels of alanine aminotransferase(ALT) and the test results of hepatitis B virus(HBV) of the newborns in two groups were observed. Results：The differences of the birth weight，Apgar scores，and the levels of ALT of the newborns in the two groups had no statistical significance(P＞0.05).The positive rate of HBsAg of the newborns in the observation group was 5.88%(2/34)，which was lower than 23.53%(8/34) of the control group，and the difference had statistical significance(P＜0.05).The positive rate of HBsAb of the newborns in the observation was 32.35%(11/34)，which was higher than 11.76%(4/34) of the control group，and the difference was statistically significant(P＜0.05). Conclusion：The application of antihepatitis B immunoglobulin combined with hepatitis B vaccine to newborns can effectively block the transmission of hepatitis B virus infection，and significantly reduce the rate of neonatal infection. Related Articles | Metrics

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Curative effect observation on Xiyanping injection in the treatment of lobar pneumonia in children ZHAO Lihong 2016, 8 (1):  39-41.  doi: 10.3969/j.issn.1674-3865.2016.01.015 Abstract ( 268 )   PDF (395KB) ( 113 )   Save Objective：To observe the curative effect of Xiyanping  injection in the treatment of lobar pneumonia in children. Methods：Using randomized，controlled method，60 cases of children with lobar pneumonia hospitalized from Jan. 2013 to Dec. 2014 were divided into treatment group(32 cases) and control group(28 cases).Control group was given the conventional treatment of symptomatic support，asthma relieving，cough relieveing，and phlegm and oxygen eliminating，while treatment group was given the conventional treatment plus Xiyanping  injection，Once daily for intravenous drip，7 days as one treatment course.Observe the curative effect after one treatment course. Results：Total effective rate of treatment group was 96.88%，superior to the control group(75.00%)，the difference being statistically significant(P＜0.05). Conclusion：The curative effect of adjunctive treatment with Xiyanping  injection is superior to the single western medicine treatment in children with lobar pneumonia. Related Articles | Metrics

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Clinical observation on atomizing inhalation of combining modified Zhike  powder with budesonide in treating pneumonia with cough in children ZHANG Xia，ZHAO Liangyu，ZHANG Fang，CHEN Min，WANG Weiwei 2016, 8 (1):  41-43.  doi: 10.3969/j.issn.1674-3865.2016.01.016 Abstract ( 361 )   PDF (425KB) ( 79 )   Save Objective：To study the therapeutic effect of atomizing inhalation of combining modified Zhike  powder with budesonide in treating pneumonia children with cough. Methods：From Jul. 2013 to Aug. 2014，a total of 132 pneumonia children with cough who received treatments in the Second Affiliated Hospital of Luohe Medical College were taken as the clinical research subjects，and these patients were randomly divided into control group(66 patients) and observation group(66 patients).The control group was treated with budesonide atomizing inhalation，and the observation group was treated with atomizing inhalation of combined modified Zhike  powder and budesonide. After treatment，we observed the clinical effect，disappearance time of cough，wheezing rale and wet rale of lung，lung Xray image recovery time and hospitalization time in these two groups. ResultsThe total effective rate of the observation group was 97.0%（64/66），which was significantly higher than that of the control group 84.8%（56/66），and the difference was statistically significant(P＜0.05).The disappearance time of cough，wheezing rale and wet rale of lung，lung Xray image recovery time and hospitalization time of children in the observation group were shorter than those of the control group，and the difference was statistically significant(P＜0.05). ConclusionAtomizing inhalation of combined modified Zhike  powder and budesonide in treatment of pneumonia children with cough can improve prognoses of children. Thus，it is worthy of promotion in clinics. Related Articles | Metrics

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Clinical observation on cerebral palsy with spleen deficiency syndrome treated by moxibustion therapy combining spine pinching 2016, 8 (1):  44-46.  doi: 10.3969/j.issn.1674-3865.2016.01.017 Abstract ( 388 )   PDF (388KB) ( 85 )   Save Objective：To observe the clinical effect of moxibustion therapy combining spine pinching in the treatment of cerebral palsy(CP) with spleen deficiency in children. Methods：Sixty patients with CP were divided into two groups randomly.Patients in the control group were treated by rehabilitation training combining moxibustion therapy，while patients in the observation group were treated by spine pinching on the basis of the treatment for the control group.GMFM-88 scales were used to judge the clinical curative effect. ResultsThirty days after treatment，the GMFM88 score was 45.27±12.12 in the observation group，which was higher than the control group，which was 40.13±13.05.The total effective rate of the observation group was 93.3%（28/30），better than 73.3% of the control group(22/30)，the difference being statistically significant（P＜0.05）. ConclusionMoxibustion therapy combining spine pinching has an evident clinical curative effect on treating spleen-deficiency syndrome of CP patients，which is worthy of promoting in clinics. Related Articles | Metrics

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Observation of clinical effects of azithromycin sequential therapy for children with mycoplasma pneumonia ZENG Guoqing，LIU Guoying，CHEN Ruilin，PENG Xiaobin 2016, 8 (1):  46-48.  doi: 10.3969/j.issn.1674-3865.2016.01.018 Abstract ( 434 )   PDF (411KB) ( 128 )   Save Objective：To observe the clinical effects of azithromycin sequential therapy for children with mycoplasma pneumonia. Methods：Totally 96 children with mycoplasma pneumonia who received treatments in Fuyong People's Hospital from June 2013 to August 2014 were taken as the research subjects，and these patients were randomly divided into the control group and the observation group，with 48 patients in each group.In the control group，they were treated with the erythromycin sequential therapy:erythromycin injection was administered intravenously once a day，continuously for 5 days，and then they were treated with the erythromycin tablets orally，3 times a day，continuously for 7 days;in the observation group，they were treated with the azithromycin sequential therapy，azithromycin injection for intravenous drip，once a day，and 5 days later the treatment was stopped for 4 days，and then azithromycin dry suspension was given orally，once a day，continuously for 3 days.Then，the treatment effect and adverse reaction of the two groups were observed. Results：The total effective rate in observation group was 97.9%(47/48)，which was higher than that in the control group ［85.4%(41/48)］，and the difference was statistically significant(P＜0.05).The incidence rate of adverse reactions in the observation group was 14.6%(7/48)，which was lower than that in the control group ［27.1%(13/48)］，and the difference was statistically significant(P＜0.05). Conclusion：In the treatment of children with mycoplasma pneumonia，the azithromycin sequential therapy can significantly improve the clinical symptoms，and it has quick effect and fewer adverse reactions with other advantages;it is safe with significant effect and it can greatly reduce the pain and improve the quality of life of children，thus it should be promoted in the clinical application. Related Articles | Metrics

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Clinical significance of urine MA，blood beta2-MG，alpha1-MG，Cys-C in pediatric early renal damageGUO Xiaomei，XU Qian，LIU Yanru，LIU Chunli GUO Xiaomei，XU Qian，LIU Yanru，LIU Chunli 2016, 8 (1):  49-52.  doi: 10.3969/j.issn.1674-3865.2016.01.019 Abstract ( 381 )   PDF (472KB) ( 107 )   Save Objective：To explore the clinical significance of urine MA，blood beta2-MG，alpha1-MG，Cys-C in pediatric early renal damage. Methods：Totally 500 cases of children with acute infection in Pediatrics Department of Baotou Eighth Hospital from November 2014 to October 2015 were included. Urine MA，blood beta2-MG，alpha1-MG，Cys-C，BUN，and Cr were detected.Those with increase in any one item were selected as kidney dysfunction observation group(108 cases).At the same time 70 healthy pediatric patients who came for regular check-ups at the OPD were selected as control group.Explore the clinical significance of urine MA，blood beta2MG，alpha1-MG，and Cys-C in different types of infectious early renal damage. Results：In observation group，urine MA，blood beta2-MG，alpha1-MG and Cys-C were all significantly higher than that of control group(P＜0.05)；BUN and Cr had no statistically significant difference between the two groups(P＞0.05).Blood alpha 1-MG in the infection group had the lowest detection rate. In virus infection group，the detection rate of urine MA，blood beta2-MG and Cys-C was different，the difference being statistically significant(P＜0.05)，in which the detection rate of blood beta2-MG was the highest. Cys-C's detection rate had no statistical difference in different infection groups. ConclusionThis study suggests the blood beta2-MG is the most sensitive in diagnosis of virus infection with early renal damage.The increase of Cys-C is not limited by the type of infection，and is a good indicator of various types of infectious renal impairment. Related Articles | Metrics

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Application value of food specific IgG antibody detection in children with recurrent respiratory tract infections LIAO Suwen，LI Bai，LIANG Ying，LIAO Bicai 2016, 8 (1):  52-55.  doi: 10.3969/j.issn.1674-3865.2016.01.020 Abstract ( 669 )   PDF (419KB) ( 117 )   Save Objective：To investigate the application value of food specific IgG antibody detection in children with recurrent respiratory tract infections. Methods：From April 2014 to April 2015，200 patients with recurrent respiratory tract infection in our hospital were selected as observation group，and 100 cases in our hospital were selected as the control group;the two groups of children were observed for 14 kinds of food specific IgG positive rate，IgE and the positive rate of eosinophils. Results：The positive rate of serum specific IgG antibody in the observation group was 76%，significantly higher than that of the control group(26%)，the difference being statistically significant(P＜0.05).The positive rates of serum specific IgG antibodies in different age groups，such as 0 to 2 years，5 to 6 years old，3 to 14 years old，were significantly higher than those in the control group，the difference being statistically significant(P＜0.01).The higher positive rates of 14 kinds of food allergic IgG in the observation group were shown in egg，milk and crab，and the positive rate of IgG in the control group were shown in egg，crab and the fish;the positive rates of IgG in egg，milk，shrimp and soybean in the observation group were higher than those in the control group(P＜0.05).The positive rate of IgG in milk in children aged 0 to 2 years old in observation group was significantly higher than that in control group(P＜0.01).The positive rate of IgG in children aged 3 to 5 years old in observation group was significantly higher than that in control group(P＜0.01).The positive rate of seafood IgG in children aged 6 to 14 years old in the observation group was significantly higher than that in the control group(P＜0.01).There was no significant difference in the positive results of IgE and eosinophils between the two groups in IgG positive children(P＞0.05). Conclusion：Food specificity has a high positive rate in recurrent respiratory tract infections，and the treatment for children should be based on the specific antibody of food. Related Articles | Metrics

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Curative effect of azithromycin combined with Xiaoer Qingfei granule in the treatment of mycoplasma pneumonia in childrenMA Yuping MA Yuping 2016, 8 (1):  56-58.  doi: 10.3969/j.issn.1674-3865.2016.01.021 Abstract ( 491 )   PDF (369KB) ( 119 )   Save Objective：To study the curative effect of azithromycin combined with Xiaoer Qingfei granule in the treatment of mycoplasma pneumonia in children. Methods：From Nov. 2012 to Sep. 2014，a total of 40 children with mycoplasma pneumonia，who received treatments in Suixian People's Hospital of Henan Province，were taken as the clinical research subjects，and these patients were randomly divided into control group(20 patients)and observation group(20 patients).Patients in the control group were treated with azithromycin，and the other patients in the observation group were treated with azithromycin combined with Xiaoer Qingfei granule(10 d a course).After treatment，we observed the clinical effect，Xray shadow disappearance time，headache relief time，and fever relief time of children in these two groups. Results：The total effective rate of the control group was 65.0%（13/20），which was significantly lower than that of the observation group 95.0%（19/20），and the difference was statistically significant(P＜0.05).The headache relief time，fever relief time，and Xray shadow disappearance time of children in the observation group were shorter than those of the control group，and the difference was statistically significant（P＜0.05）. Conclusion：Azithromycin combined with Xiaoer Qingfei granule in treatment of mycoplasma pneumonia can rapidly improve the clinical symptoms and signs of children. Related Articles | Metrics

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Influence of chronotherapy of Fubei powder on infantile pneumonia of phlegm-heat stagnating in lung LONG Haixu，WANG Mengqing 2016, 8 (1):  58-61.  doi: 10.3969/j.issn.1674-3865.2016.01.022 Abstract ( 350 )   PDF (518KB) ( 108 )   Save Objective：To explore the treatment effect of chronotherapy of Fubei powder on infantile pneumonia of phlegm-heat stagnating in lung. Methods：A total of 90 patients with infantile pneumonia admitted to Hunan University of TCM from May 2013 to August 2014 were randomly divided into three groups（n=30) according to medication time；Three groups were given conventional western medicine treatment and Fubei powder.The administration time of first group was 7:00 to 9:00，the second group 9:00 to 11:00，the third group 15:00 to 19:00.After 7 days of treatment，the treatment outcomes of the three groups were compared. Results：The clinical symptoms were significantly improved in all the 3 groups，and the third group had a statistically higher overall response rate than the other two groups(P＜0.017)，while the first and second group had no statistical difference in treatment effect(P＞0.017). Conclusion：Chronotherapy of Fubei powder has significant effect on infantile pneumonia of phlegm-heat stagnating in lung，and can be widely used in clinic. Related Articles | Metrics

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Effect of phentolamine in the treatment of pediatric intestinal obstruction caused by diarrheaLIANG Dianzhe LIANG Dianzhe 2016, 8 (1):  62-64.  doi: 10.3969/j.issn.1674-3865.2016.01.023 Abstract ( 349 )   PDF (391KB) ( 129 )   Save Objective：To observe the effect of phentolamine in the treatment of children with (incomplete) intestinal obstruction. Methods：Eighty children with (incomplete) intestinal obstruction hospitalized in the Pediatric Department of Wuwei Liangzhou Hospital form June 2012 to June 2015，were randomly divided into control group(n=40) and treatment group(n=40).The control group was given water fasting，gastrointestinal decompression，rehydration，enema and other comprehensive treatment，and for the treatment group，on the basis of the treatment for control group，phentolamine was given;observe clinical symptoms improvement and recovery time after treatment in the two groups. Results：The cure rate of the treatment group(48 h，72 h，4～6 d) was 37.5%（15/40），95.0%（38/40） and 100.0%（40/40） respectively，while in the control group it was 20.0%（8/40），70.0%（28/40） and 82.5%（33/40）.The cure rate at 72 h and 4～6 days in treatment group was significantly higher than that in the control group，the difference being statistically significant(P＜0.05). Conclusion：Phentolamine is effective in improving in clinical symptoms and shortening the course of the disease in the treatment of children with (incomplete) intestinal obstruction，which is worthy of popularied and applied in pediatric clinics，and it is safe and effective. Related Articles | Metrics

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Observation on the clinical effects of minocycline combined with methylprednisolone in the treatment of children with refractory mycoplasma pneumoniae pneumonia RAO Fuguang，XIONG Biao，WANG Peiqin 2016, 8 (1):  64-66.  doi: 10.3969/j.issn.1674-3865.2016.01.024 Abstract ( 634 )   PDF (399KB) ( 112 )   Save Objective：To observe the clinical effects of minocycline combined with methylprednisolone in the treatment of children with refractory mycoplasma pneumoniae pneumonia(RMPP). Methods：Totally 88 children with RMPP who accepted treatments in Department of Pediatrics，Maternity and Child Health Care Hospital of Longgang District，from March 2014 to March 2015，were taken as the research subjects，and these patients were randomly divided into the control group and the observation group，with 44 patients in each group.In the control group，they were treated with azithromycin for routine treatment，while in the observation group，they were treated with azithromycin for 1 week and then oral minocycline was taken，medication continuing for 5 d;at the same time they were treated with the intravenous infusion of methylprednisolone for 5 d，then it was changed to oral prednisone，the dosage being reduced gradually according to patients' condition for 7 days.Then，the symptom relief time，hospitalization time，inflammation index and adverse reaction of the two groups were observed. Results：The cough relief time，cooling time and hospitalization time of children in the observation group were significantly shorter than those in the control group，and the difference was statistically significant(P＜0.05).After treatment，the levels of inflammatory markers of the two groups were significantly lower than before treatment，and the difference was statistically significant(P＜0.05).After treatment，the C reaction protein，ESR and WBC count in the observation group were significantly lower than those in the control group，and the difference was statistically significant(P＜0.05).After two weeks of treatment，the lung shadow absorption rate in the observation group was 81.82%(36/44)，which was significantly higher than that in the control group［43.18%(19/44)］ and the difference was statistically significant(P＜0.05). Conclusion：In the clinical treatment for RMPP，combination with methylprednisolone and minocycline can rapidly improve the clinical symptoms and thus improve the treatment effect. Related Articles | Metrics

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Clinical observation on treatment for lobar pneumonia with Xiehuo Jiedu decoction LIN Yu 2016, 8 (1):  67-69.  doi: 10.3969/j.issn.1674-3865.2016.01.025 Abstract ( 360 )   PDF (399KB) ( 107 )   Save Objective：To observe the clinical effect of oral Xiehuo Jiedu decoction in the treatment of children with lobar pneumonia. Methods：A total of 382 cases of lobar pneumonia were selected and randomly divided into two groups：the control group and the treatment group.The control group was given a simple antiinfection treatment of western medicine，while the treatment group was given Xiehuo Jiedu decoction treatment in addition to the western treatment，one dose daily，twice a day，about 15～40 mL each time，for two weeks as a treatment course.At the end of treatment，observe the clinical efficacy. ResultsThe total effective rate of the treatment group was 96.3%，and the total effective rate was 71.2% in the control group，showing that the treatment group was significantly better than the control group with statistical difference（P＜0.01）.The serum levels of C reactive protein in the two groups were significantly decreased compared with those before treatment，but the decrease in the treatment group was more obvious than that in the control group，the difference being statistically significant（P＜0.01）.The fever time，antibiotics use time and length of hospital stay in treatment group were significantly less than that of the control group，and the difference had statistical significance(P＜0.01). Conclusion：In the treatment of infantile lobar pneumonia Xiehuo Jiedu decoction can significantly reduce the C reactive protein level，shorten the time of fever-relieving，antibiotic use and hospital stay，and thus improve the clinical efficacy，which is worthy of clinical application. Related Articles | Metrics

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Clinical evaluation of transumbilical single laparoscopic treatment for acute appendicitis in children ZHANG Tian 2016, 8 (1):  70-72.  doi: 10.3969/j.issn.1674-3865.2016.01.026 Abstract ( 544 )   PDF (345KB) ( 125 )   Save Objective：To observe the clinical effect of transumbilical single laparoscopic treatment for acute appendicitis in children. Methods：A total of 123 children were admitted to Hunan Children's Hospital from August 2012 to April 2015 for acute appendicitis.According to treatment methods，these children were divided into two groups:the observation group(66 cases) and the control group(57 cases).The control group was given conventional laparoscopic surgery and the observation group received transumbilical single laparoscopic treatment.Compare the clinical effect，operation-related indexes and complication incidences between the two groups. Results：The total effective rate was 97.0%(64/66) in the observation group，significantly higher than that of the control group，which was 84.2%(48/57)，and the difference was of statistical significance(P＜0.05).The average operative time of the observation group was significantly shorter than that of the control group，and the bleeding volume in the observation group was much less than in the control group，the difference was statistically significant(P＜0.01).The complication incidences after treatment were significantly lower in the observation group than in the control group，and the difference was statistically significant(P＜0.05).There was no significant difference in the recovery time of intestinal function and the hospital stay(P＞0.05). Conclusion：In the treatment of acute appendicitis in children，transumbilical single laparoscopic treatment is better than conventional laparoscopic surgery，and it is safe with good effect，which should be used in clinic. Related Articles | Metrics

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Efficacy of homemade Qiwei Lishi powder on children with chronic diarrhea XIE Xiaoshu 2016, 8 (1):  73-74.  doi: 10.3969/j.issn.1674-3865.2016.01.027 Abstract ( 363 )   PDF (280KB) ( 94 )   Save Objective：To observe the effect of homemade Qiwei Lishi powder on children with chronic diarrhea. MethodsTotally 110 cases of chronic diarrhea treated in the Second People's Hospital of Luohe from March 2013 to March 2015 were collected，and were randomly divided into observation group(60 cases) and the control group(50 cases).The control group received conventional treatment，and observation group were added traditional Chinese medicine Qiwei Lishi powder，7 d as a course of treatment.Two groups of children were recorded clinical effects and adverse reactions. Results：The total effective rate was 96.7%(58/60) in observation group，significantly higher than 82.0%(41/50) in control group，the difference being statistically significant(P＜0.05);the incidence of adverse reactions in observation group(1.7%，1/60) was significantly lower than the control group［12.0%(6/50)］，the difference being statistically significant(P＜0.05). Conclusion：Qiwei Lishi powder is safe and effective in the treatment of children with chronic diarrhea. Related Articles | Metrics

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Clinical observation on the treatment for children with viral myocarditis and arrhythmia by Chinese and western medicin TANG Qimin，SONG Chaogong 2016, 8 (1):  75-78.  doi: 10.3969/j.issn.1674-3865.2016.01.028 Abstract ( 419 )   PDF (538KB) ( 130 )   Save Objective：To observe the clinical effect of the integrative treatment with Chinese and western medicine for children with viral myocarditis and arrhythmia according to classification and stage. Methods：A total of 80 children admitted to the First Affiliated Hospital of Henan TCM College from July 2014 to April 2015 for viral myocarditis were included in the study，and they were randomly divided into observation group(40 cases) and control group(40 cases).Both groups were given conventional western treatment of myocardial nutrition，and the observation group was added Chinese medicine decoction differentiated by classification and stage.The treatment course was 1 month for both groups，and then the curative effect was evaluated by TCM clinical standard of diagnosis and curative effect as well as the myocardial enzyme indexes before and after treatment. Results：The total effective rate of observation group was 94.7%(36/38)，which was significantly higher than 70.3%(26/37) of control group，and the difference was statistically significant(P＜0.05).All myocardial enzyme indexes were significantly lower after treatment in both groups，and the indexes in the observation group were even much lower，the difference being of statistical significance(P＜0.05). Conclusion：The clinical effect of integrated treatment with Chinese and western medicine is significant for children with viral myocarditis and arrhythmia according to classification and stage. Related Articles | Metrics

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Observation on the effect of different doses of gamma globulin in the treatment of children with severe HFMDLIAO Xianhui 2016, 8 (1):  79-81.  doi: 10.3969/j.issn.1674-3865.2016.01.029 Abstract ( 376 )   PDF (396KB) ( 140 )   Save Objective：To observe the clinical effect of gamma globulin at different doses in the treatment of children with severe HFMD. Methods：A total of 96 children with HFMD at stage Ⅱ and Ⅲ were treated in Zunyi Maternity and Child Health Care Hospital from June 2013 to June 2015，and they were divided randomly into two groups:the small-dose group and the large-dose group，with 48 cases in each group.The two groups were given conventional and symptomatic treatment，and in addition to that，they were injected intravenously different doses of gamma globulin，with 1 g/kg for the small-dose group and 2 g/kg for the large-dose group.Compare the time for clinical symptoms to disappear，the time of being clinically cured，the hospital stay，the complications and the hospitalization expenses between the two groups. Results：There was no statistical difference in the time for clinical symptoms to disappear，the time of being clinically cured and the hospital stay(P＞0.05).The complication incidence was 16.7%(8/48) in the large-dose group，higher than the small-dose one，which was 2.1%(1/48)，and the difference was statistical significance(P＜0.05).The expense in the small-dose group was lower. Conclusion：The effect of gamma globulin at different doses is similar and significant in the treatment of severe HFMD.When the dose is 1 g/kg，the treatment expense is lower and the complication incidence is lower，so it is worthy of being clinically applied. Related Articles | Metrics

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Observation on the effect of Tanreqing injection in the treatment of pediatric pneumoniaLI Feng LI Feng 2016, 8 (1):  82-84.  doi: 10.3969/j.issn.1674-3865.2016.01.030 Abstract ( 252 )   PDF (455KB) ( 95 )   Save Objective：To observe the clinical effect of Tanreqing injection in the treatment of infantile pneumonia. Methods：Totally 126 cases of children with pneumonia hospitalized from November 2011 to March 2015 in Shenyang City Huanggu District Central Hospital of Pediatrics were included in the study，and according to odd or even number of the date of admission they were divided into observation group(76 cases) and control group(50 cases).Fever and cough relieving and antiinfection treatment was given to the control group; the observation group was added Tanreqing injection besides the treatment for control group，with 5% glucose solution for intravenous injection，once a day，for 7 days as a course of treatment.After the course of treatment，the clinical symptoms disappearing time，hospitalization time and the total effective rate of two groups were observed. Results：In the observation group the time for fever，cough and wheezing to disappear，pulmonary rales disappearance time and hospitalization time were shorter compared with the control group，the difference being statistically significant(P＜0.05). In the observation group，the total effective rate was 97.4%(74/76)，significantly higher than that of control group ［86.0%(43/50)］，the difference being statistically significant(P＜0.05). Conclusion：The clinical effect of Tanreqing injection is significant in the treatment of infantile pneumonia. Related Articles | Metrics

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Analysis of risk factors in children with cerebral palsy WANG Chunli，LONG Xuhao 2016, 8 (1):  85-87.  doi: 10.3969/j.issn.1674-3865.2016.01.031 Abstract ( 355 )   PDF (365KB) ( 102 )   Save Objective：To analyze the relevant risk factors of cerebral palsy(CP) and provide a reference for the prevention of the disease. Methods：The 50 children with cerebral palsy hospitalized in Pediatric Rehabilitation Center from October 2013 to March 2015 were studied as observation group.The 100 healthy children were selected as control group.A 1∶2 matched casecontrol study was conducted.Complete the questionnaire by consulting the medical records of the hospital and inquiring the parents of the children.The survey items included pregnancyinduced hypertension，multifetus，premature rupture of the amniotic fluid，premature birth，low weight at birth，neonatal asphyxia and intracranial hemorrhage(ICH).All data were analyzed with Logistic regression. Results：Oneway analysis showed that premature birth，low weight at birth，multifetus，pathological jaundice，neonatal asphyxia，premature rupture of the amniotic fluid，hypoxicischemic encephalopathy and infection were risk factors for cerebral palsy in children(P＜0.05).The multivariate analysis showed that premature birth，low weight at birth，pathological jaundice，neonatal asphyxia and multifetus were main risk factors. Conclusion：The relevant risk factors of CP are various，so taking precautious measures during gestation and perinatal period is important. Related Articles | Metrics

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Correlation between development of hip joint and the ambient muscle tone in schoolage children with cerebral palsy XU Jingli，HUANG Shaoang，YE Changqing，FAN Yanping，CAI Lulu 2016, 8 (1):  88-90.  doi: 10.3969/j.issn.1674-3865.2016.01.032 Abstract ( 265 )   PDF (354KB) ( 85 )   Save Objective：To explore the correlation between the development of hip joint and the ambient muscle tone in schoolage children with cerebral palsy. Methods：Totally 56 children with cerebral palsy(41 spastic children，9 athetoid children，4 dystaxia children，2 children mixed with spasticity and athetoisis，37 diplegia，16 quadriplegia and 2 hemiplegia) in Guangzhou Rehabilitation Experimental School were recruited. All subjects received Xray examinations to analyze the value of MP.Both the muscle tone of hip flexation，adduction，and intorsion and the muscle strength of hip extention，abduction and extorsion were tested. ResultsIn 56 patients，21 cases（37.50%） showed generally normal hip development，32 cases（57.14%） showed half dislocation of hip joint and 3 cases（5.36%） showed total dislocation of hip joint. Spearman correlation analysis showed that the value of MP was positively correlated with the muscle tone of hip flexation，adduction，and intorsion（P＜0.05） and was negatively related to the muscle strength of hip extention，abduction and extorsion（P＜0.05）. ConclusionThere is correlation between the development of hip joint and the ambient muscle tone in schoolage children with cerebral palsy. Related Articles | Metrics

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Effect of Xiaoer Chaigui Tuire granule combined with ribavirin on the immunity of children with acute upper respiratory tract infection LU Yanhong 2016, 8 (1):  91-93.  doi: 10.3969/j.issn.1674-3865.2016.01.033 Abstract ( 586 )   PDF (326KB) ( 64 )   Save Objective：To investigate the effect of Xiaoer Chaigui Tuire granule combined with ribavirin on the immunity of children with acute upper respiratory tract infection. Methods：A total of 216 cases of acute upper respiratory tract infection in children admitted to Laibin People's Hospital from Jan. 2014 to June 2015 were randomly divided into three groups:control group Ⅰ(62 cases) treated with Xiaoer Chaigui Tuire granule，control group Ⅱ(68 cases) given ribavirin for injection，and the observation group(86 cases) receiving treatment of Xiaoer Chaigui Tuire granule combined with ribavirin;another 30 normal children were chosen during the same period as the normal control group.Compare and analyze the changes of immunity in the children of each group before and after the treatment. Results：Before treatment，CD3+，CD4+，and CD4/CD8 were remarkably lower in observation group and control group Ⅰ and Ⅱ than in normal control group，while CD8+ was higher，the difference being of statistical significance(P＜0.05)；the improvement of CD3+，CD4+，CD8+，and CD4/CD8 in observation group was better than in control group Ⅰ and Ⅱ，and the difference being statistically significant(P＜0.05);the total effective rate in observation group was 97.7%(84/86)，remarkably higher than control group Ⅰ(83.9%，52/62)，the difference being statistical significant(P＜0.017);Pearson linear correlation analysis showed that the clinical effect in child patients was positively related to the immunity indexes of CD3+，CD4+，CD8+ and CD4/CD8. ConclusionThe treatment with Xiaoer Chaigui Tuire granule combined with ribavirin for acute upper respiratory tract infection is probably through enhancing the immune function of human body. Related Articles | Metrics

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Study on the relationship between syndrome characteristics and cough attack time in infants with pneumonia mycoplasma infection XUN Chunzheng，WANG Mengqing 2016, 8 (1):  94-96.  doi: 10.3969/j.issn.1674-3865.2016.01.034 Abstract ( 305 )   PDF (337KB) ( 114 )   Save Objective：To study the relationship between syndrome characteristics and attack time of cough in infantile pneumonia mycoplasma infectious，then to provide guidance for the clinical diagnosis and treatment. Methods：A total of 115 cases of infantile pneumonia mycoplasma postinfectious cough were admitted to the First Affiliated Hospital of Hunan University of TCM from Feb. 2013 to Feb. 2014.We collected the clinical data and counted the distribution of syndromes，then analyzed the correlation between syndromes and attack seasons and attack time of cough. Results：The most common syndromes of infantile pneumonia mycoplasma postinfectious cough were syndrome of windheat invading lung，syndrome of windcold attacking lung and syndrome of deficiency of Lung Qi.The attack time of cough caused by windcold attacking lung had a tendency to focus on Xu Shi，but there was no statistical difference (P＞0.05).The attack time of cough caused by windheat invading lung focused on Mao Shi and Xu shi，while the attack time of cough caused by deficiency of Lung Qi had no rules to follow. Conclusion：The attack time of infantile pneumonia mycoplasma postinfectious cough has a certain rule，and there exists certain correlation between clinical syndromes and attack time. Related Articles | Metrics

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Study on psychological behavior intervention of infantile anorexia ZHANG Chongzhou，LI Xuefang 2016, 8 (1):  97-99.  doi: 10.3969/j.issn.1674-3865.2016.01.035 Abstract ( 404 )   PDF (513KB) ( 113 )   Save Etiologies of infantile anorexia were analyzed.To cure infantile anorexia and reduce the recurrence，individualized psychological behavior intervention should be performed，such as strengthening health education，controlling cold drink and fruit，emphasizing dinner，nursing correctly，using complementary foods reasonably，developing good eating habits，controlling snacks，correcting the partial eclipse，emphasizing psychological adjustment and allocating dietary scientifically. Related Articles | Metrics

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The status survey of children with precocious puberty in Chinese cities ZHU Diqing，ZHU Hong 2016, 8 (1):  100-102.  doi: 10.3969/j.issn.1674-3865.2016.01.036 Abstract ( 1429 )   PDF (502KB) ( 184 )   Save Objective：To investigate the status of patients with precocious puberty in Chinese cities，and provide a theoretical basis for making effective prevention strategy，and promoting clinical standardization and personalized treatment of precocious puberty. Methods："Precocious Puberty Research in Chinese cities" activities began in the period between March and December 2014.Among a total of 2 687 questionnaires，1 714 were included in the final statistical analysis. Results：The survey of patients with city distribution were mainly in 10 cities，the top three being Chongqing(21.28%)，Changzhou(9.26%) and Shanghai(8.37%).Girls dominated the survey，and male to female ratio was about 1∶16;In secondary inspection，patients diagnosed with central precocious puberty accounted for 75.79% by GnRH stimulation test.Initial diagnosis of patients with central precocious puberty accounted for 88.91%.In all patients with central precocious puberty，bone age was higher than the actual average age at about 1.65 years old and the differences were statistically significant（P＜0.001）. Conclusion：The patients with central precocious puberty in Chinese cities are generally older. In order to avoid missing the best time for intervention and treatment，great importance should be attached to the disease screening，and early detection，early diagnosis and early treatment must be done. Related Articles | Metrics

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Experience of Shuangjie Tounong powder in the treatment of pediatric rotten tonsillitis GUO Ranran，QIN Yanhong 2016, 8 (1):  103-104.  doi: 10.3969/j.issn.1674-3865.2016.01.037 Abstract ( 332 )   PDF (351KB) ( 113 )   Save Professor Qin Yanhong has been working on pediatric diseases for many years，and she is especially good at diagnosis and treatment of pediatric diseases.She has summed up many special prescriptions for treating diseases after more than 20 years of repeated deliberation.Rotten tonsillitis，a common and frequently occurring disease in pediatrics，is widely concerned by doctors because of its acute onset，severe illness，complicated transformation and repeated occurrence.Prof.Qin use selfmade Shuangjie Tounong powder in treatment of pediatric rotten tonsillitis，which has achieved a significant therapeutic effect in clinic. Related Articles | Metrics

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Experience in using Gordon fruit and motherwort in the treatment of purpura renal proteinuria by strengtheningspleen and promoting blood circulation WANG Long，LIU Yangyang，GAO Min，DING Ying 2016, 8 (1):  105-107.  doi: 10.3969/j.issn.1674-3865.2016.01.038 Abstract ( 334 )   PDF (417KB) ( 106 )   Save Purpura nephritis is one of the common secondary glomerular diseases in pediatrics.The permeability of glomerular filtration membrane increases，a large amount of plasma protein leaks out，which exceeds the renal tubular reabsorption capacity and is discharged out of the body，forming proteinuria.Professor Ding thinks that the nature of purpura renal proteinuria lies in the spleen and kidney deficiency，so based on years of clinical experience，she uses Gordon fruit and motherwort flexibly to strengthen the spleen and promote blood circulation，which results in good effect. Related Articles | Metrics

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Treatment of infant asthma with internal and external TCM therapy YANG Yuliang,DIAO Bensu 2016, 8 (1):  107-109.  doi: 10.3969/j.issn.1674-3865.2016.01.039 Abstract ( 576 )   PDF (478KB) ( 123 )   Save This paper introduces professor Dr. Diao Bensu's clinical experience in the treatment of infant asthma with internal and external TCM therapy.To ventilate the lung and dissipate phlegm and invigorate the spleen and stomach is the main way in acute phase.Remission stage treatment should be to invigorate spleen and remove phlem.Its significant curative effect has been verified by clinical tests，and it has few toxic side effects. Related Articles | Metrics

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Experience of using honeycomb to treat HenochSchonlein purpura in childrenZHAI Wensheng，ZHAO Yongwang，LI Bing.The First Affiliated Hospital of Henan College of Traditional Chinese Medicine，Zhengzhou 450000，China. ZHAI Wensheng，ZHAO Yongwang，LI Bing 2016, 8 (1):  110-112.  doi: 10.3969/j.issn.1674-3865.2016.01.040 Abstract ( 326 )   PDF (418KB) ( 136 )   Save HenochSchonlein purpura is a systemic vasculitis with small vessel vasculitis as the main pathological change.During the clinical treatment，it relapses easily.Etiology and pathogenesis of the disease has not been fully clarified.Many studies suggest that it is associated with the immune mechanism，inflammatory mechanisms and so on.In the process of curing the disease，basing on syndrome differentiation，the author uses the hive's antiinflammatory and immunosuppressive effects to effectively reduce the purpura's repetition and shorten the process of the disease，which obtains satisfactory results. Related Articles | Metrics

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Application of detail management in nursing care of children with diarrhea LU Jing 2016, 8 (1):  112-114.  doi: 10.3969/j.issn.1674-3865.2016.01.041 Abstract ( 362 )   PDF (441KB) ( 106 )   Save Objective：To observe the effect of detail management in the nursing of pediatric diarrhea，and to observe the effect of detail management to improve the level of pediatric nursing. Methods：A total of 200 hospitalized children with diarrhea were randomly divided into observation group and control group.Control group was given routine nursing care，and the observation group was given routine nursing care plus detail management;observe the number of nursing dispute or nursing errors and degree of satisfaction. Results：The observation group had disputes or nursing errors，while the control group had nursing disputes or nursing errors in 5 cases，the difference between the two groups being statistically significant(P＜0.05).The questionnaire survey showed that the satisfaction degree of the observation group was 99%，and that of the control group was 91%，the difference being statistically significant(P＜0.05). Conclusion：In the nursing care of children with diarrhea，the detail management can improve the satisfaction of children and family members reduce the number of nursing disputes and the incidence of nursing errors. Related Articles | Metrics

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Nursing experience of children with multiple finger deformity WU Mingyu 2016, 8 (1):  115-117.  doi: 10.3969/j.issn.1674-3865.2016.01.042 Abstract ( 348 )   PDF (391KB) ( 114 )   Save Objective：To summarize the surgical treatment and nursing effect of multifinger deformity. Methods：Totally 53 cases of children with multiple finger deformities were treated with surgery and given rehabilitation nursing. Results：All the 53 cases were cured and discharged after operation and scientific nursing. Conclusion：Surgical treatment and the full range of nursing can help children to get better recovery of finger function. Related Articles | Metrics

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Nursing experience of low temperature plasma radiofrequency ablation in treatment of allergic rhinitis in childrenLI Dan LI Dan 2016, 8 (1):  117-119.  doi: 10.3969/j.issn.1674-3865.2016.01.043 Abstract ( 260 )   PDF (434KB) ( 158 )   Save Objective：To summarize the treatment method and nursing experience in treating allergic rhinitis in children with low temperature plasma radiofrequency ablation. Methods：A total of 65 children with allergic rhinitis who were treated by low temperature plasma ablation in the Fifth People's Hospital from May 2011 to February 2015 were chosen.After treatment，they were given antibiotics for antiinfection and antiinflammatory.Clean the nasal secretions every day.The treatment lasted for 6 to 8 weeks.Psychological nursing care was given before treatment，and conventional nursing care was performed before，during and after the treatment.Followup was made respectively 1 week，4 weeks，3 months，6 months and one year later.Observe the recovery of nasal cavity and evaluate the treatment result. Results：In the 65 cases of children receiving low temperature plasma ablation treatment，39 cases were cured，22 cases improved，4 cases ineffective，and the total effective rate was 93.85%.Follow up results showed that all the patients had no nasal mucosa atrophy，nasal cavity adhesion or olfactory dysfunction，and no side effects occurred. Conclusion：The low temperature plasma ablation technique has little damage to the nasal mucosa.It can be used as an alternative treatment instead of medicine，laser and microwave in the treatment of allergic rhinitis. Related Articles | Metrics

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Effect of farinfrared radiation heat preservation and infant incubator to keep warm on the vital signs and body quality of premature infants LIN Lini，CHEN Ci，HUANG Qiaoyan 2016, 8 (1):  120-122.  doi: 10.3969/j.issn.1674-3865.2016.01.044 Abstract ( 410 )   PDF (362KB) ( 117 )   Save Objective：To explore the effect of farinfrared radiation heat preservation and infant incubator to keep warm on the vital signs and body quality of premature infants. Methods：Eighty premature infants were chosen who were hospitalized in Shiyan People's Hospital of Baoan District from Jan. 2013 to May 2014，and they were randomly divided into two groups:the observation group(40 cases) and the control group(40 cases).Compare the breath，heart rate，milk volume and body quality at different time point of hospital stay(on admission，4 d，7 d and 14 d) between the two groups. Results：There was no statistical difference in breath and heart rate at different time points(P＞0.05).There was no statistical difference in milk volume and body quality on admission between the two groups(P＞0.05).After being kept warm by different methods，the milk volume and body quality in the observation group were significantly higher than the control group on 4 d，7 d and 14 d of admission，and there was statistical difference(P＜0.05). Conclusion：Compared with farinfrared radiation heat preservation，infant incubator is more fit for keeping warm for the premature infants，which can effectively increase the breath and heart rate and has significant clinical effect. Related Articles | Metrics

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Experience in psychological nursing intervention for children with dental caries YANG Li，CONG Fang 2016, 8 (1):  122-124.  doi: 10.3969/j.issn.1674-3865.2016.01.045 Abstract ( 355 )   PDF (439KB) ( 102 )   Save Objective：To summarize the effect of psychological nursing intervention on dental caries in children. MethodsA total of 198 cases of caries of deciduous teeth in children who were treated in Shenyang Stomatological Hospital from March 2013 to March 2015 were included in the study.According to the odd or even number of their visits，they were divided into two groups: the observation group and the control group，with 99 cases in each. The control group was given conventional nursing care，and the observation group received psychological nursing intervention in addition to the treatment for control group. After treatment，compare the clinical treatment time and coordination degree between the two groups. Results：The total coordination rate of observation group was 90.9%(90/99)，higher than that of control group［74.7%(74/99)］，and the difference was statistically significant (P＜0.05).The treatment time of observation group was (14.8±3.6)min，lower than that of control group，(19.5±6.3)min，and the difference was statistically significant(P＜0.05). Conclusion：Scientific treatment and psychological nursing intervention can help the children to actively cooperate in the treatment and shorten the treatment time. Related Articles | Metrics