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25 August 2024, Volume 16 Issue 4 Previous Issue    Next Issue

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Effect of progressive resistance training on the activity and participation ability of children with spastic cerebral palsy SONG Fanxu, ZHAO Hongbo, PANG Wei 2024, 16 (4):  277-280.  Abstract ( 194 )   PDF (1073KB) ( 16 )   Save ObjectiveTo explore the effects of progressive resistance training on the activity and participation abilities of children with cerebral palsy at the ICFCY level.MethodsThe study subjects were 40 children with spastic diplegic cerebral palsy who were admitted to the Third Affiliated Hospital of Jiamusi University from January to December 2021.They were randomly divided into a control group and an observation group,with 20 cases in each group.The control group received routine rehabilitation training,while the observation group received progressive resistance training and routine rehabilitation training,with each group receiving treatment for 3 months.Before and after treatment,these children were evaluated for their activity and participation abilities using the WeeFIM,PEDI,ADL,and TOP,respectively.ResultsThe WeeFIM,PEDI,ADL,and TOP scores in the observation group were all higher than those in control group after treatment,and the differences were of statistical significance (P<005).ConclusionThe progressive resistance training can effectively improve the activity and participation ability of children with spastic diplegic cerebral palsy. Related Articles | Metrics

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Effects of hand-arm bilateral intensive training combined with traditional Chinese medicine massage on upper limb function in children with hemiplegic cerebral palsy LIANG Lubo, HE Qiangyong, LI Peiqiong, ZHU Xingming, LUO Tingwei, MENG Zhiyang 2024, 16 (4):  281-286.  Abstract ( 112 )   PDF (1112KB) ( 106 )   Save ObjectiveTo investigate the impact of combining Chinese medicine massage with hand-arm bilateral intensive training on children with hemiplegic cerebral palsy.MethodsA total of 62 children undergoing rehabilitation treatment in Foshan First People′s Hospital between January 2021 and June 2023 were selected,and they were randomly divided into control group (30 cases) and observation group (32 cases).The control group received eight weeks of bilateral intensive training for the hands and arms,while the observation group underwent both Chinese medicine massage and hand-arm bilateral intensive training for the same duration.The QUSET and PEDI scales were employed for pre- and post-training evaluations in both groups,and data analysis was conducted to compare differences between the two groups.ResultsAfter the treatment,both groups exhibited improved scores on the QUSET scale (P<0.05) in isolated movement area,weight-bearing area and total scores,with the observation group achieving higher scores than the control group (P<0.05).Similarly,the PEDI scale demonstrated improved scores for both groups after the treatment in self-care ability,moving ability and social skills of the functional skill area and care-giver assistance area(P<0.05).Concerning self-care ability and moving ability of the functional skill area and the self-care ability of the care-giver assistance area,the observation group′s scores surpassed those of the control group after the treatment (P<0.05).ConclusionThe combination of hand-arm bilateral intensive training with Chinese medicine massage is more effective in improving upper limb function in children with hemiplegic cerebral palsy than hand-arm bilateral intensive training alone. Related Articles | Metrics

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Analysis of the effect of lower limb walking machine for assistant training on gait improvement in children with spastic hemiplegia and cerebral palsy SUN Shengyue, ZHOU Dayong, LU Weina, FANG Guiwei, LIU Ning, DU Li 2024, 16 (4):  286-290.  Abstract ( 79 )   PDF (1183KB) ( 16 )   Save ObjectiveTo investigate the effect of lower limb walking machine for assistant training on the improvement of gait in children diagnosed with spastic hemiplegia and cerebral palsy.MethodsSixteen hemiplegic children who were treated in Harbin Medical University Affiliated Fourth Hospital from May 2022 to November 2023 were randomly divided into control group (n=8) and experimental group (n=8).The control group was given routine rehabilitation training, and the experimental group was given lower limb walking machine for assistant training on this basis.The training time was 30 minutes per time, 6 times a week.Gait parameters such as stride length, unilateral support time, gait cycle,and swing time of children before and after training were collected,and the data changes before and at 8 weeks after intervention were analyzed.ResultsAfter treatment,there were significant differences between the two groups in the stride length of the affected side,the time of unilateral support,the gait cycle of the affected and healthy sides and the swing time of the affected side (P<0.05);the changes after routine rehabilitation training and lower limb walking machine for assistant training were better than those after routine rehabilitation training,and the children tended to walk correctly.ConclusionLower limb walking machine for assistant training can improve the gait cycle of the affected side of hemiplegic children,increase the stride length and unilateral support time of the affected side,prolong the swing time of the affected side,shorten the swing time of the healthy side,and improve the hemiplegic gait. Related Articles | Metrics

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Comparative study on the effect of different Chinese herbs on γ-aminobutyric acid contents in germinated brown rice using HPLC method ZHAN Jie, LIU Nairong, LI Jinghui, WEI Ruijiao 2024, 16 (4):  291-296.  Abstract ( 128 )   PDF (1492KB) ( 11 )   Save ObjectiveBased on the theory of constitution analysis,to compare and analyze the effects of different kinds of medicinal and edible herbs on the content of GABA in germinated brown rice,so as to provide theoretical basis for the development of medicinal diet of brown rice for children with different constitutions.MethodsThe experiment included three groups:blank group (brown rice group),control group (germinated brown rice group) and TCM germinated brown rice group.The TCM germinated brown rice group was again divided into 9 subgroups:qi-tonifying group (Huang Qi rice,Shan Yao rice,Bai Bian Dou rice),yin-nourishing group (Yu Zhu rice,Huang Jing rice,Gou Qi rice,Sang Ye rice),blood-supplementing group (Sang Shen rice,Long Yan Rou rice),yang-assisting group (Du Zhong rice,Gan Jiang rice),qi-regulating group (Chen Pi rice,Gan Song rice),sputum-resolving group (Xing Ren rice,Zi Su Zi rice,Lai Fu Zi rice),blood-activating group (Tao Ren rice,Jiang Huang rice),dampness-eliminating group (Fu Ling rice,Yi Yi Ren rice),and heat-clearing group (Jue Ming Zi rice,Xia Ku Cao rice,He Ye rice,Dan Dou Chi rice).Among them,the qi-tonifying group,yang-assisting group,yin-nourishing group and blood-supplementing group involved germinated brown rice with Chinese herbs for invigoration,and dampness-eliminating group,sputum-resolving group,heat-clearing group,qi-regulating group and blood-activating group involved germinated brown rice with Chinese herbs for reducing excess.HPLC method was used to quantitatively analyze the contents of GABA in brown rice,germinated brown rice and germinated brown rice with different compound of Chinese herbs,a linear regression equation of the mass concentration of GABA and the absorbance value was established,and the GABA content in the samples was calculated and compared.ResultsCompared with blank group,the content of GABA was significantly higher in all groups of germinated brown rice except for DU Zhong rice,Gan Song rice and Tao Ren rice (P<0.05).Compared with control group,the content of GABA significantly increased in the germinated brown rice of Huang Qi,Shan Yao,Bai Bian Dou,Yu Zhu,Huang Jing,Gou Qi,Sang Ye,Sang Shen,Long Yan Rou,Yi Yi Ren,Xing Ren,Zi Su Zi,Lai Fu Zi,Dan Dou Chi,Chen Pi and Jiang Huang (P<0.05).The content of GABA in germinated brown rice of Gan Jiang,Fu Ling,Jue Ming Zi,Xia Ku Cao and He Ye was higher than that in brown rice,but lower than the ordinary germinated brown rice,and the differences were of statistical significance (P<0.05).The comparison based on the functions of Chinese herbs showed that the GABA content was higher in germinated brown rice with Chinese herbs in qi-tonifying group,yin-nourishing group and blood-supplementing group than in yang-assisting group (P<0.05);the GABA content was higher in germinated brown rice with Chinese herbs in qi-regulating group and sputum-resolving group than in blood-activating group (P<0.05).The GABA content in Huang Qi,Huang Jing,Sang Shen,Long Yan Rou,Chen Pi,and Sang Ye was significantly higher than in other Chinese herbs,and also significantly higher than in the corresponding germinated brown rice with Chinese herbs (P<0.05);the GABA content was significantly higher in the germinated brown rice of Shan Yao,Bai Bian Dou,Yu Zhu,Fu Ling,Yi Yi Ren,Lai Fu Zi,Jue Ming Zi and Dan Dou Chi than in the corresponding Chinese herbs (P<0.05).ConclusionThe Chinese herbs of tonifying qi,nourishing yin,supplementing blood and regulating qi can be used to develop functional foods for regulating emotion,enhancing memory,improving sleep and regulating digestive function. Related Articles | Metrics

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Research progress of Chinese and western medicine in enuresis children with occult spina bifida LING Hao, MO Yanling, WANG Yanchao, LI Lan 2024, 16 (4):  297-301.  Abstract ( 118 )   PDF (1092KB) ( 19 )   Save Enuresis is a common disease in pediatric clinic,its etiology is complex,the course of disease is long,and it is easy to relapse,which has adverse effects on children′s physical and mental health.Modern clinical studies have found that most children with enuresis have occult spina bifida in X-ray examination.In western medicine it is believed that occult spina bifida leads to enuresis in children by causing occult nerve dysfunction at the sacral spinal cord level,weakening bladder function,adding delayed effects of the urination center,causing sleep dyspnea and inhibiting renin-angiotensin-aldosterone system.In traditional Chinese medicine the disease is analyzed from the supervision vein and kidney.This paper discusses the correlation between occult spina bifida and enuresis in children and the possible mechanism of action from the aspects of Chinese and western medicine.At the same time,the present treatment methods in Chinese and western medicine and prognosis of children with occult spina bifida are also described.It is hoped that this article can provide some theoretical basis for the future study of enuresis children with occult spina bifida. Related Articles | Metrics

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Current situation and prospect of TCM research in autism spectrum disorder ZHANG Yuehua, XIE Yuanyuan 2024, 16 (4):  301-304.  Abstract ( 248 )   PDF (1073KB) ( 165 )   Save Autism spectrum disorder(ASD) is a group of neurodevelopmental disorders with a high rate of mental disability and an increasing incidence in recent years.The etiology of ASD is unknown,and there are no specific drugs or specific treatment methods.At present,the mainstream international treatment methods mainly rely on behavioral intervention and education to improve the core symptoms,and auxiliary drug therapy to improve the co-morbidity.In recent years,the research and exploration of TCM in the field of autism have been further.TCM therapy has unique advantages in improving the core disorders and comorbidities of autism,but it also faces difficulties and challenges.In this paper,the exploration of traditional Chinese medicine in the field of autism in recent years is reviewed to provide a certain theoretical basis and evidence for the treatment of autism by traditional Chinese medicine. Related Articles | Metrics

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Research progress in the mechanism of Chinese medicine in the treatment of tic disorders based on network pharmacology ZHONG Mingxiu, ZHANG Di, LIU Ying 2024, 16 (4):  305-308.  Abstract ( 154 )   PDF (1065KB) ( 20 )   Save With the development of society and the influence of the environment,the incidence of tic disorders (TD) has increased year by year in recent years,and it has become one of the more common pediatric diseases in clinical practice.The treatment for TD in western medicine is mainly based on dopamine (DA) and central α2 receptor agonists,combined with psychotherapy,which has certain efficacy,but its adverse reactions make some children intolerant.The holistic concept and treatment based on syndrome differentiation in traditional Chinese medicine have significant advantages in safety and efficacy in the prevention and treatment of TD.Single herbs,drug pairs and compounds in traditional Chinese medicine have multi-target and multi-pathway regulatory effects,which are consistent with the core idea of network pharmacology in modern theory.Therefore,network pharmacology methods are gradually being accepted and adopted by traditional Chinese medicine to study its mechanism of action.This paper reviews the research and application progress of network pharmacology in the mechanism of action of traditional Chinese medicine in the treatment of TD,and expounds the existing problems in the research,in order to provide reference for the application of network pharmacology in the research of traditional Chinese medicine in the treatment of TD. Related Articles | Metrics

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Review of Chinese and western medicine literature on infraorbital dark circles in children WANG Hai, LI Yanlin 2024, 16 (4):  309-313.  Abstract ( 137 )   PDF (1405KB) ( 29 )   Save There are many names for infraorbital dark circles in children,which are confusing,and there are few epidemiological studies.Although the local pathology is clear,the fundamental etiology is controversial.Analysis of the local anatomy of the inferior palpebral vein,infraorbital vein,lacrimal venous plexus,facial vein,suborbital space and infraorbital lymph nodes has shown that the possibility of obstruction of infraorbital venous return caused by nasal and adenoid diseases is greater.Traditional Chinese medicine classics have rich discussion on dark circles,and there is a close correlation between the eyes and the five viscera in terms of physiology and pathology,especially the liver,spleen,and kidney.In addition,the meridian theory and the theory of qi,blood and body fluid can also explain this phenomenon,not just "spleen deficiency".Misdiagnosis and missed treatment should be avoided in clinical practice. Related Articles | Metrics

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Complications of IgA vasculitis in different organs in 5 children and literature review DING Lele, DING Ying, WEI Jinhui, XU Shanshan, MEI Xiaofeng, LI Jingang 2024, 16 (4):  314-319.  Abstract ( 73 )   PDF (1378KB) ( 19 )   Save ObjectiveTo improve the understanding of IgA vasculitis and the level of diagnosis and treatment by analyzing its clinical characteristics in children.MethodsRetrospectively analyze the clinical characteristics,auxiliary examinations,treatment and prognosis of the 5 children with IgA vasculitis admitted to the Department of Pediatrics of the First Affiliated Hospital of Henan University of Chinese Medicine from April 2018 to April 2021.ResultsThere were 4 males and 1 female in 5 cases of IgA vasculitis.The median age was 6.There was 1 case of lung damage,1 case of liver damage,1 case of spleen damage,1 case of intestinal damage and 1 case of epididymis damage.During the course of the disease,4 cases had abdominal pain and 2 cases had joint pain.All children had typical skin purpura.There were 2 cases without abnormalities in urine testing and 3 cases with abnormalities in urine testing,including 1 case of simple proteinuria and 2 cases of hematuria and proteinuria.All children were improved after treatment with integrated traditional Chinese and Western medicine.ConclusionIgA vasculitis is the most common vascular inflammatory disease dominated by IgA deposition in childhood.In addition to purpura,abdominal pain and joint swelling and pain are the most common clinical manifestations.The disease is very likely to combine other organ damage and it′s even life-threatening,such as severe lung injury.When patients have other systemic symptoms,relevant examinations should be completed in time to clarify the condition and to avoid treatment delay. Related Articles | Metrics

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Study on the effectiveness of rehabilitation training for dysphagia in children with severe pneumonia after tracheal  intubation and extubation MO Haili, LIAO Chan, LIANG Xinting, MENG Meiqin 2024, 16 (4):  320-323.  Abstract ( 88 )   PDF (1069KB) ( 12 )   Save ObjectiveTo explore the clinical application effect of swallowing function training combined with pacifier sucking in children with acquired dysphagia after tracheal intubation and extubation in severe pneumonia,and to provide guidance and reference for promoting in-depth development of rehabilitation training for dysphagia after tracheal intubation and extubation in children with severe pneumonia.MethodsA retrospective analysis was conducted in 120 children with severe pneumonia admitted to the Department of Critical Care Medicine of our hospital from July 2019 to September 2023 who underwent endotracheal intubation(intubation time≥5 days) and developed post-extubation swallowing dysfunction.Take the beginning of the study on swallowing function training combined with pacifiers in July 2021 as the boundary.The cases before the study was carried out were set as the control group,and the cases when the study was carried out and implemented were set as the observation group,with 60 cases in each group.The control group received routine care after extubation,while the observation group received swallowing function training combined with pacifier sucking.After the intervention,the results of recovery of swallowing function,the rate of aspiration by mistake,the incidence of aspiration pneumonia,reintubation rate,the rate of returning to ICU and other indicators were evaluated.ResultsThe standardized swallowing assessment(SSA) scores of the observation group were significantly lower than those of the control group at 4 hours，24 hours,48 hours and 72 hours after intervention,and on discharge,and the difference was statistically significant(P<0.01).The total effective rate of improvement in swallowing function of children in the observation group was 100.0%(60/60),which was higher than 86.7%(52/60) in the control group,and the difference was statistically significant(P<0.01).The total incidence rate of complications in the observation group was 16.7%(10/60),which was lower than 73.3%(44/60) in the control group,among which the rate of aspiration by mistake,the incidence of aspiration pneumonia, reintubation rate and the rate of returning to ICU were all lower than those in the control group,and the difference was of statistical significance(P<0.05).ConclusionSwallowing function training combined with pacifier sucking can effectively improve the swallowing function of children with dysphagia after tracheal intubation and extubation in severe pneumonia and reduce the occurrence of related complications. Related Articles | Metrics

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Clinical study on continuous renal replacement therapy in neonatal sepsis-related acute kidney injury LI Xiaoqing, CHEN Jiangbin, CHEN Xinhua, YANG Hansong, WANG Ruiquan 2024, 16 (4):  324-328.  Abstract ( 80 )   PDF (1097KB) ( 13 )   Save ObjectiveTo investigate the application value of continuous renal replacement therapy (CRRT) in the treatment of neonatal sepsis-associated acute kidney injury (AKI).MethodsA total of 26 neonates with sepsis-associated AKI diagnosed and treated from June 2017 to August 2021 were selected for retrospective analysis.All of them were given CRRT;observe the duration of CRRT treatment,length of hospital stay,complications and 28 d survival rate.The following indexes before treatment,at 12 h,24 h and 48 h after treatment as well as at the end of the treatment were also recorded:mean arterial pressure (MAP),pH value,oxygenation index,lactic acid,serum creatinine (Scr),blood urea nitrogen (BUN),cystatin C (CysC),tumor necrosis factor-α (TNF-α),interleukin-6 (IL-6),Toll-like receptor 4 (TLR4),and neutrophil gelatinase-associated lipocalin (NGAL).The one-way repeated measures ANOVA was used to analyze the changes in the clinical indexes at different treatment time.ResultsContinuous renal replacement was successfully completed in 26 neonates with sepsis-associated AKI,with a survival rate of 88.46%(23/26) at 28 days.The duration of CRRT treatment was (73.52±12.65) h and the duration of hospitalization was (10.25±2.32) d.MAP,oxygenation index,and pH at 12 h,24 h,48 h and at the end of treatment were higher than those before treatment,and urine volume was more than before treatment,while lactic acid,Scr,BUN,CysC,TNF-α,IL-6,TLR4 and NGAL were all lower than before treatment,and the differences were statistically significant (P<0.05).There were 4 cases of hypotension (15.38%),3 cases of hypothermia (11.54%) and 3 cases of catheter blockage (11.54%) during the treatment of CRRT.The 7 d NBNS score of 7 patients was less than 35 points,and 2 patients had abnormal Vojta postural reflex.ConclusionCRRT has ideal effects and is safe in the treatment of neonatal sepsis-related AKI,which can effectively reduce inflammatory factors,correct water and electrolyte disorders,and avoid further kidney damage,but there is a risk of long-term brain injury,and clinical attention should be paid to it. Related Articles | Metrics

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Congenital myasthenia with neonatal laryngeal wheezing as the first manifestation:a case report TANG Yingli, CHEN Hongyan, WANG Xiaofeng, ZHANG Meiyan 2024, 16 (4):  329-333.  Abstract ( 71 )   PDF (1610KB) ( 6 )   Save The patient,male,who was born 21 h before,was admitted to the hospital due to abnormal voice for 17 h.No special treatment was given after admission,and relevant auxiliary examinations were completed without showing any abnormalities.The patient was on breastfeeding normally and had a good reaction.The throat sounds disappeared before being discharged.After discharge,the patient experienced recurrent respiratory distress.Further whole-exon genetic testing showed that there were 2 heterozygous mutations of COLQ gene:heterozygous mutation of c.806dup and heterozygous mutation of c.706del,which was decided to be pathogenetic variation.The disease associated with it is congenital myasthenia syndrome type 5,belonging to autosomal recessive inheritance. Related Articles | Metrics

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Exploring the rehabilitation,diagnosis and treatment of autism spectrum disorder in traditional Chinese medicine based on Professor Xu Rongqian′s "Theory of Shen,Hun,Yi,Po,Zhi" ZHU Ling, YU Minfeng, LIU Zhenhuan, LI Nuo, LIU Ying, LI Longhua, HUANG Yinying, LIN Xiaohong, CHEN Kanghua 2024, 16 (4):  333-338.  Abstract ( 68 )   PDF (1117KB) ( 14 )   Save The occurrence of autism spectrum disorder (ASD) involves multiple organ dysfunction.Professor Xu Rongqian′s "Theory of Shen,Hun,Yi,Po,Zhi" can explain various core clinical manifestations of ASD.Through in-depth analysis of the functions of Shen,Hun,Yi,Po,Zhi,it has been discovered that the occurrence of this disease is closely related to the "Five Organs Shen",especially to the heart-Shen,liver-Hun,spleen-Yi,and kidney-Zhi.The theoretical system of "treatment for both Xing and Shen" is used in clinical practice to guide the treatment of ASD,which achieves good therapeutic effects by benefiting Xing and qi. Related Articles | Metrics

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Treatment for pediatric adenoid hypertrophy by Professor Ye Weicheng using Xu′s pediatric theory of strengthening the spleen and resolving phlegm and masses ZHOU Junhui, ZHAO Jun, YE Weicheng, CUI Chen 2024, 16 (4):  339-341.  Abstract ( 226 )   PDF (1040KB) ( 119 )   Save The clinical incidence of adenoid hypertrophy in children is increasing year by year.At present,surgery is the first choice in clinical treatment,but the disease is likely to recur after surgery,and the patients often have adenoid facial expression and secretory otitis media;in severe cases,it may cause complications such as obstructive sleep apnea hypopnea syndrome,which may seriously affect the children′s growth,physical and mental health,and the quality of their lives in the long run.Professor Ye Weicheng applies Xu′s pediatric theory of strengthening the spleen and resolving phlegm and masses to the treatment of adenoid hypertrophy,and uses Erchen decoction to strengthen the spleen and resolve phlegm;in addition,Xia Ku Cao is used for resolving masses;the treatment has achieved great clinical effects. Related Articles | Metrics

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An analysis of the tri-jiao differentiated treatment for pediatric damp-heat cough in Shu area YANG Hang, LI Xi, LI Mingzhang, WU Xinchen 2024, 16 (4):  342-345.  Abstract ( 68 )   PDF (1061KB) ( 17 )   Save Shu area has the features of basin topography and hot and humid climate,and the people there love spicy food,which results in more cases of children with damp and heat constitution.Because of children′s physiological characteristics of weak lungs and spleen,the dampness and heat can easily invade the children′s body.The dampness and heat is trapped in tri-jiao (upper,middle and lower jiao),all causing cough,so the children in Shu area often have damp-heat cough.The cause of tri-jiao cough is analyzed,and the tri-jiao treatment is differentiated.In general,the tri-jiao treatment is based on the dampness and heat,and is related to ventilating the lungs.It is expected to provide lines of thinking for the characteristic treatment of damp-heat cough in children in Shu area. Related Articles | Metrics

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Analysis of experience in treating pediatric eczema based on the "visceral collaterals" GAO Yiwen, FENG Xiaochun 2024, 16 (4):  345-348.  Abstract ( 80 )   PDF (1062KB) ( 16 )   Save Eczema is a clinically common skin disease with obvious exudative tendency in infants and young children.In recent years,with the application of a large number of biochemicals and the changes in environment,the incidence of eczema in children has gradually increased.The disease is persistent and difficult to cure and has a high recurrence rate,which seriously affects children′s daily diet and sleep,and may also interfere with their growth and development.Therefore,active treatment is needed.The collaterals are the organic channels connecting the internal organs,the external limbs,and the upper and lower parts of the human body,and they are also the channels for the invasion and spread of evil qi.The theory of visceral collaterals originated from the "Huangdi Neijing",and gradually became a theory in the Qing Dynasty after being supplemented and developed by medical practitioners throughout history.Visceral collaterals theory has obvious advantages in treating chronic diseases,persistent diseases,diseases difficult to cure,and skin diseases.Modern doctors do not attach enough importance to the theory of collaterals,and its clinical application is limited;especially,children′s development is usually incomplete,and there are many doctors who don′t know how to treat through collaterals.In clinical practice,visceral collaterals theory is used in the differential treatment of childhood diseases,integrating visceral syndrome differentiation with the theory of collateral diseases.It is found that the pathogenesis of this disease is that "the collaterals of spleen and lungs are damaged by dampness and heat",and the disease is divided into three stages and is treated based on syndrome differentiation.During treatment,a combination of internal and external treatment is used,focusing on unblocking the collaterals,so that the dampness and heat can be reduced internally and dispersed externally,which effectively shortens the course of the disease and reduces the pain of children.This provides effective new ideas and methods for the clinical practice of traditional Chinese medicine in pediatrics. Related Articles | Metrics

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Discussion of Professor Zhang Baoqing′s medication rules in treating tic disorders in children based on data mining ZHANG Haochen, ZHANG Baoqing, WANG Xinxin, PAN Yueli 2024, 16 (4):  349-354.  Abstract ( 83 )   PDF (1846KB) ( 10 )   Save ObjectiveTo explore Professor Zhang Baoqing′s medication rules in treating tic disorders(TD) in children based on data mining.MethodsFrom May 2022 to April 2023,the TCM prescriptions by Professor Zhang Baoqing in treating TD were collected.IBM SPSS Statistics 23.0 and IBM SPSS Modeler 18.0 were used to analyze the types,frequency,property and taste and the functioning meridians of the drugs used by Professor Zhang Baoqing.The drug groups in the prescription and core prescriptions were summarized.ResultsA total of 265 prescriptions for TD were collected,involving 110 TCM drugs.The efficacy was mainly for relieving,tonifying and clearing.The drug properties were mainly warm and mild followed by slightly cold and cold,and the taste was mainly bitter,pungent and sweet.The main channels were lung,liver,spleen and stomach.The common drug pairs were obtained by association rule analysis,such as Radix notopterygiae-Radix saposhnioviae,Radix gardenia-licorice,cicada-licorice,bupleurus-fried white peony,etc.The cluster analysis showed 6 potential drug groups.ConclusionProfessor Zhang Baoqing pays equal attention to "internal wind"and "external wind" in the treatment of TD,and often treats TD from lung,liver and spleen. Related Articles | Metrics

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Clinical study on the treatment for upper airway cough syndrome of damp-heat type in children with Shangjiao Xuanbi decoction and acupoint application XIONG Jiaxiu, ZHAO Xiaomin 2024, 16 (4):  354-358.  Abstract ( 87 )   PDF (1112KB) ( 19 )   Save ObjectiveTo observe the clinical efficacy of Shangjiao Xuanbi decoction and acupoint application in the treatment of upper airway cough syndrome(UACS) of damp-heat type in children.MethodsFrom January 2021 to July 2023,80 cases of UACS of damp-heat type diagnosed in the pediatric outpatient clinic of the Second Affiliated Hospital of Jiangxi University of TCM were selected and were randomly divided into a control group and an observation group,with 40 cases in each group.The control group was given symptomatic treatment such as anti-infection and anti-allergy treatment,while the observation group was given Shangjiao Xuanbi decoction and acupoint application on this basis.After 3 courses of treatment the VAS scores and the scores of main clinical symptom grading were used for evaluation,and the clinical efficacy,adverse reactions and recurrence rate were compared.ResultsThe total effectiveness rate was 95.0%(38/40) in the observation group,significantly higher than that in the control group (80.0%,32/40),and the difference was statistically significant (P<0.05).The clinical symptom score was significantly lower in the observation group than in the control group (P<0.05).The VAS scores of the two groups were lower after treatment than before treatment,and the score in the observation group was even lower (P<0.05).There was no statistical difference in the incidence rate of adverse reactions between the two groups during the treatment (P>0.05).The recurrence rate of the observation group in the 3-month follow-up was 7.89%(3/38),obviously lower than that of the control group (28.13%,9/32),and the difference was of statistical significance (P<0.05).ConclusionThe combination of Shangjiao Xuanbi decoction and acupoint application is effective and safe in the treatment of UACS of damp-heat type in children,which can reduce the recurrence rate,and deserves clinical promotion and application. Related Articles | Metrics

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Clinical effect of Xiaoer Qingre Huaji powder on febrile convulsion in children CHENG Shen, LI Ling, CHEN Yaqin, CHEN Yuyan 2024, 16 (4):  359-362.  Abstract ( 105 )   PDF (1119KB) ( 14 )   Save ObjectiveTo observe the clinical effect of Xiaoer Qingre Huaji powder in the prevention and treatment of febrile convulsion in children.MethodsA total of 102 children with febrile convulsion were selected from the pediatric outpatients and inpatients of Zhejiang Hospital of Traditional Chinese Medicine from January 2021 to December 2022,and they were randomly divided into control group (50 cases) and observation group (52 cases).The control group was given conventional treatment,and the observation group was given oral treatment of Xiaoer Qingre Huaji powder on the basis of the the treatment for control group.The two groups were observed continuously for 3 days,and relevant indicators were collected.Three months was set as a follow-up course.During the follow-up,the control group was given diazepam to prevent convulsion,and the observation group was given Xiaoer Qingre Huaji powder to prevent convulsion,and they were followed up for 1 year.The time of fever relief,the number of recurrent convulsions,and the change in TCM syndrome score before and after treatment were counted.The number of convulsions in the two groups during follow-up was counted.ResultsThe body temperature of the two groups were decreased with treatment time,with the observation group being lower than the control group at 6h,24h,48h and 72h of treatment,and the difference was statistically significant (P<0.05).During the whole process of treatment,the fever was effectively controlled in the observation group,and the the number of reaching peak (body temperature≥39 ℃) was 0.53±0.62,significantly lower than the control group (1.65±2.72);in the 72 hours of treatment,the difference was statistical (P<0.05).At the same time,the TCM syndrome score was significantly lower than that of control group,and the difference was statistically significant (P<0.05).There was no statistical difference in the incidence of adverse reactions (P>0.05) between the two groups.The two groups were followed up for 1 year,the observation group did not have convulsion,while the control group had (0.55±0.55) times of convulsion,the observation group being significantly better than the control group,and the difference was statistically significant (P<0.01).ConclusionXiaoer Qingre Huaji powder is effective in preventing and treating febrile convulsion in children.It can shorten the fever duration,significantly reduce the frequency of recurrent convulsion,and prevent febrile convulsion recurrence effectively,which is worth clinical promotion and application. Related Articles | Metrics

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Clinical experience of Professor Sun Liping in the treatment of pediatric anorexia based on constitution theory WANG Xinhe, SUN Liping 2024, 16 (4):  363-366.  Abstract ( 84 )   PDF (1066KB) ( 19 )   Save Pediatric anorexia is one of the most common spleen and stomach diseases in pediatrics,which is common in the children aged 1 to 6 years,and its incidence is increasing year by year.Long-term anorexia will result in immunodeficiency,repeated respiratory infection,malnutrition,growth and development retardation and sleep disorders,which does damage to physical and mental health of children and their development.In western medicine it is believed that the disease is mainly related to diet habits,feeding methods and natural environment.The treatment of traditional Chinese medicine is based on the differentiated diagnosis and treatment,so it has great advantages over western medicine treatment.Professor Sun Liping is good at treating the disease by starting from the overall concept,taking the symptoms and signs as the superficial manifestations and the constitution as the root cause,and the treatment based on the constitution theory has achieved good results in the children with pediatric anorexia. Related Articles | Metrics

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Professor Ju Wei′s experience in treating anorexia in children based on viscera JIANG Huili, LIU Yitong, FU Shanshan, MIAO Ping 2024, 16 (4):  366-368.  Abstract ( 134 )   PDF (1041KB) ( 17 )   Save Childhood anorexia is a common disease with frequent onset.Professor Ju Wei believes that childhood anorexia is mainly due to the middle jiao stagnation of diet,excessive intake of cold drugs,and the inactivation of liver and spleen.Practically the cause of the disease is still the spleen dysfunction.Based on careful study of the pathogenesis,the treatment should focus on promoting digestion,clearing heat,soothing liver,and activating blood circulation.For the children with stagnation,Xihuang powder combined with Sanxian decoction should be used.For those with food stagnation and depression,Baohe pills combined with Zengye decoction should be used.For the chronic cases with congestion,Yigong powder combined with Siwu decoction can be used.For the children with liver depression,Sini powder is used.In the course of medication,the guidance of living habits is effective. Related Articles | Metrics